Antipruritic Market Outlook 2024 to 2034

The global antipruritic market size is projected to surpass a valuation of USD 16.2 billion by 2034. Our healthcare analysts opine that antipruritic manufacturers can expect a CAGR of 4.2% through 2034, with a current valuation of USD 10.9 billion in 2024.

Attributes Market Insights
Market Value 2023 USD 10.5 billion
Market Value 2024 USD 10.9 billion
Market Value 2034 USD 16.2 billion
CAGR 2024 to 2034 4.2%
Market Share of Top 5 Countries 60.8%

Pruritus is a complex process that frequently happens with skin conditions, including atopic dermatitis and urticaria, and may harm quality of life. Additionally, it might be a sign of an underlying medical condition, such as hyperthyroidism or cholestasis, or it might just be the result of dry skin, especially during the chilly winter months.

Therapy focuses on treating the itching first, then addressing the underlying cause. Herbal therapies, prescription and over-the-counter (OTC) drugs, hydrotherapy, phototherapy, and UV therapy are all possible forms of treatment.

Key Market Highlights:

  • To improve efficacy and patient compliance, ongoing research and development are anticipated to drive advances in antipruritic formulations such as topical creams, ointments, and innovative delivery modalities.
  • A significant trend is the development of biological treatments for skin conditions that cause pruritus. Biologics have the potential to change the therapeutic landscape by providing focused and effective therapies for specific illnesses.
  • With the growing frequency of skin illnesses such as eczema, psoriasis, and dermatitis, there is an increased emphasis on creating antipruritic remedies suited to these specific dermatological problems.
  • Incorporating new technologies, such as AI-driven diagnostics or smart devices for monitoring and controlling pruritus, have emerged as antipruritic market trends.
  • The incorporation of antipruritic management into telehealth systems and electronic health records represents a new trend, particularly given the increased popularity of remote healthcare services.

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Historical Performance of Antipruritic Market (2019 to 2023) Vs. Forecast Outlook (2024 to 2034)

Attributes Details
Antipruritic Market Size (2019) USD 9.1 billion
Antipruritic Market Size (2023) USD 10.5 billion
Antipruritic Market CAGR (2019 to 2023) 4.1%

The market observed a growth of 4.1% during 2019 and 2023. The global market for antipruritic held nearly 64.6% of the overall USD 15.7 billion skin treatment market shares in 2023.

The most frequent dermatologic symptom reported by patients is pruritus. It is associated with a variety of skin conditions, the majority of which are characterized by primary lesions such as vesicles, plaques, and papules.

The underlying causes of pruritus are still unknown, making it difficult for healthcare practitioners to control itching in individuals with severe pruritus adequately. There are typically discrepancies between causative and symptomatic approaches to pruritus therapy. A common strategy for navigating the broad terrain of pruritus therapy is to categorize these alternatives according to their underlying causes.

Causative therapy aims to identify and treat the underlying illness causing the itching. Symptomatic treatment hides the itch through treatments such as cooling, heating, or counter-irritation (e.g., scratching). To provide relief sooner, symptomatic treatment and addressing the underlying disease process may be used. The popular therapeutic options are classified as symptomatic therapy and management.

Disruptive technical advancements, increasing healthcare investments, and health system optimization are driving the swift development of the medical and drug industries. Modern medical institutions, ambulatory care centers, and clinics throughout the world are deliberately adopting cutting-edge technological technologies and equipment into their operations to improve efficiency and competitiveness.

The global market's revenue growth is fuelled by factors such as rising chronic illness incidence, rapid improvements in the healthcare and medical sectors, widespread use of new instruments and techniques, and increased funding from various public and private sectors.

Furthermore, rising emphasis on drug discovery, rising need for precision medicine, widespread deployment of home care services and point-of-care diagnostics, and increased investments in R&D activities are likely to boost global market revenue and profit during the projected timeframe.

These factors are projected to impact the growth of the industry worldwide positively. With a CAGR of 4.2%, the industry is predicted to develop significantly during the following decade.

Key Opportunities in the Antipruritic Market

Chronic pruritus, a growing health problem, significantly impacts quality of life. Ongoing research has revealed new pathways and itch receptors, which has improved our understanding of these aspects. Expectations are strong that these latest insights are going to encourage the development of ground-breaking treatments for this frequently ignored and inconvenient ailment.

The administration of medications that reduce neural sensitization to pain, such as gabapentin, pregabalin, SSRIs, and norepinephrine antidepressants, either singly or in combination, is now required for the therapeutic management of chronic pruritus.

In the future, adopting a variety of topical and systemic medicines that focus on the different receptors and neurological pathways mediating distinct forms of itch would improve the quality of life for millions of pruritic patients.

Sabyasachi Ghosh
Sabyasachi Ghosh

Principal Consultant

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Factors that Present a Restrictive Outlook for the Market

Because of the condition's complex etiology and various contributing factors, treating chronic pruritus (CP) remains challenging. Despite the well-known antipruritic properties of traditional pharmacotherapy, such as topical therapy, light therapy, and systemic therapy, these strategies typically fail to provide significant relief for affected individuals.

Despite the wide range of therapy options, chronic pruritus is still challenging to treat. Several antipruritic treatments are still used off-label as of right now. There are currently just a few effective topical treatments for itching, and existing itch management techniques do not cover most unmet needs.

Furthermore, few published works employ general health metrics to evaluate CP, and there are very few economic statistics on the cost of chronic pruritus. According to the American Academy of Dermatology's (AAD) National Burden of Skin Disease report, pruritus-related disorders in the United States incur a yearly treatment expense of USD 294 million and an opportunity cost of USD 107 million (2017).

According to Luk et al. (2020), people with CP have an annual financial burden of USD 1,067 because of both direct and secondary medical costs. The impact of stress, anxiety, depression, and functional incapacity on the patient and their loved ones as a result of the condition are examples of what are known as intangible costs that are not taken into account by current techniques of cost assessment.

During the forecast period, the market is expected to experience barriers in its growth trajectory due to a significant financial burden, limited evidence-based data, and parameters associated with existing treatment alternatives.

Country-wise Insights

Countries CAGR (2024 to 2034)
United States 37.4%
China 8.9%
Germany 4.70%
United Kingdom 5.10%
Japan 3.20%

The United States Emerges as the Leading Market for Antipruritic

The United States dominated the antipruritic market with 37.4% of market shares in 2023. The antipruritic market size in the United States is estimated to rise at a 4.30% CAGR through 2034. The country has a vast healthcare system includes comprehensive patient care and reimbursement provisions. Moreover, with greater patient awareness regarding various treatment modalities and options for pruritus treatments, the country holds a leading stance within the global market.

China is Considered a Lucrative Market for Antipruritic

China captured a value share of 8.9% in the global market in 2023. The demand for antipruritic treatments is projected to surge at a 6.90% CAGR through 2034. It has been observed in several population-based studies that in Chinese patients, the frequency and severity of pruritus vary with skin conditions, skin type, age, and gender.

According to GBD 2019, young and middle-aged demographics have a higher illness burden from acne. Nearly 9.4% of the world’s population suffers from acne, making it the 8th most widespread condition globally. The market for antipruritics is driven by the increased prevalence of skin diseases in China, providing key producers with opportunities to expand within the country.

Sales Outlook for Germany in the Global Market

Germany held around 5.7% of the antipruritic market in 2023. The market for antipruritic in Germany is predicted to thrive at a 4.70% CAGR through 2034. In Germany, a surprisingly high number of pruritus sufferers, particularly those with specific localizations on the body, have unmet medical needs. This factor promotes opportunities for established manufacturers within the country to promote and develop novel therapeutics, addressing these unmet needs, hence propelling growth throughout the forecast period.

Rising Telemedicine Adoption Surges Market Growth in the United Kingdom

The United Kingdom held nearly 3.50% of the market shares in 2023. The demand for antipruritic in the United Kingdom is estimated to rise at a 5.10% CAGR through 2034. The introduction of telemedicine services in the United Kingdom has unlocked the door to online consultations and prescriptions for antipruritic drugs, increasing access to healthcare services. Government subsidies or incentives for research and development could appeal to pharmaceutical businesses to invest in producing new and improved antipruritic remedies.

Technological Developments in Dermatology Spur Expansion in Japan

Japan held nearly 5.20% of the market shares in 2023. The antipruritic market size in Japan is projected to surge at a 3.20% CAGR through 2034. Skincare and appearance are highly valued in Japanese society. A robust cultural preference for preserving good skin increases demand for antipruritic treatments, particularly those with aesthetic advantages. Japan is famous for its technological advances. Integration of cutting-edge technology, such as smart skincare devices or AI-driven diagnostic tools for dermatological diseases, could represent a differentiating element in market growth.

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Category-wise Insights

Immunosuppressants Experience High Adoption on a Global Scale

Segment Immunosuppressants (Drug Type)
Value Share (2024) 31.3%

Immunosuppressants held a share of around 31.3% in the global market in 2023. This is due to the effectiveness of oral immunosuppressants such as cyclosporine, mycophenolate mofetil, and azathioprine in treating itching caused by inflammatory disorders like atopic dermatitis. Furthermore, systemic corticosteroids can also be administered to reduce inflammation in extreme situations of chronic pruritus.

The most effective way to reduce itching in atopic dermatitis is to manage the inflammation with topical or systemic immunosuppressive medications effectively.

Psoriasis Disease is a Large Concern within the Global Market

Segment Psoriasis (Disease Type)
Value Share (2024) 33.2%

Psoriasis held around 33.2% of the global market in 2023. Psoriasis is a prevalent, chronic illness that has no cure. According to the 2019 report on the worldwide disease burden, there have been 4,622,594 reported cases of psoriasis globally in that year. The age range of 60 to 69 years has the maximum prevalence of psoriasis overall, with a roughly equal frequency between men and women.

The burden is substantially heavier in North American and European countries with high incomes and high SDI indices. To help reduce the disease burden of psoriasis globally, this factor fuels the interest of manufacturers in the market in the development of novel therapies.

Oral Route of Administration is Highly Preferred in the Antipruritic Market

Segment Oral (Route of Administration)
Value Share (2024) 39.8%

The oral route of administration held a share of around 39.8% in the global market in 2023. This is due to the usage of oral antihistamines for the symptomatic alleviation of pruritus. Oral antihistamines of the first or second generations, such as cetirizine and loratadine, are widely recommended. First-generation oral antihistamines include diphenhydramine and hydroxyzine.

Moreover, due to the ease of administration of oral medication dosages, the oral route of administration gains a more significant share within the global market.

Hospital Pharmacies Distribution Channel Reap Great Benefits

Segment Hospital Pharmacies (Distribution Channel)
Value Share (2024) 30.4%

Hospital pharmacies held around 30.4% of the global market in 2023. Several institutional pharmacies provide commonly prescribed medications for pruritus at subsidized rates, thus propelling sales of antipruritics within these settings. Moreover, with the ease of dispensing, presence of branded and generic drug options, as well as greater accessibility to patients, this segment holds a dominant share within the global market.

Competitive Landscape

Key players are enhancing their research and development activities to launch novel products. The expansion of their product range and efforts to improve their pipelined products are two other strategic acquisitions and partnerships with key businesses.

Recent Developments

  • In May 2023, Biofrontera announced that the care foam Belixos ACTIVE CARE was added to the active cosmetic series Belixos. Topical dermatitis and psoriasis patients' go-to treatment for basic or extensive skin issues can benefit from using Belixos ACTIVE CARE, a skin-soothing care foam for irritated and itchy skin.
  • In October 2022, Sonoma Pharmaceuticals, Inc., a leader in the global healthcare industry that develops and produces stabilized hypochlorous acid (HOCl) products based on patented Microcyn technology for a variety of applications, including wound, eye, oral, and nasal care, as well as dermatological conditions, announced the launch of Reliefacyn Advanced Itch-Burn-Rash-Pain Relief Hydrogel and Rejuvacyn Advanced Skin Repair Cooling Mist for consumers in the United States for over-the-counter use.
  • The new atopic dermatitis therapy Moizerto Ointment (generic name: difamilast), available in 1 percent and 0.3 percent formulations, was introduced in Japan on June 1, 2022, according to a statement from Otsuka Pharmaceutical Co., Ltd. (Otsuka).
  • The United States FDA authorized Pfizer's CIBINQO (abrocitinib) in January 2022 for use in individuals with moderate-to-severe atopic dermatitis.
  • In May 2020, Sanofi received United States FDA approval for its Dupixent (dupilumab), the first biologic medicine for children aged 6 to 11 years with moderate-to-severe atopic dermatitis.

Report Scope as per Antipruritics Industry Analysis

Attribute Details
Forecast Period 2024 to 2034
Historical Data Available for 2019 to 2023
Market Analysis USD billion for Value
Key Regions Covered North America, Latin America, Europe, South Asia, East Asia, Oceania, the Middle East and Africa (MEA)
Key Countries Covered United States, Canada, Brazil, Mexico, Argentina, Germany, Italy, France, Spain, United Kingdom, Russia, BENELUX, China, Japan, South Korea, India, Indonesia, Thailand, Malaysia, Australia, New Zealand, GCC Countries, Turkey, North Africa, South Africa
Key Companies Covered AbbVie Inc.; Allergan, Merck & Co., Inc.; Amgen Inc.; Pfizer Inc.; Cara Therapeutics; Enteris BioPharma; NeRRe Therapeutics; Menlo Therapeutics; XBiotech Inc.; Ipsen Pharma; Eledon Pharmaceuticals, Inc.; Amorepacific; RDD Pharma, Ltd; Novartis AG; AstraZeneca; Sanofi; Sun Pharmaceutical Industries Ltd.; Teva Pharmaceutical Industries Ltd.; Takeda Pharmaceutical Company Limited; Cipla Ltd.
Key Market Segments Covered Drug, Disease, Route of Administration, Distribution Channel, and Region
Pricing Available upon Request

Key Segments Covered in Antipruritics Industry Research

By Drug:

  • Corticosteroids
  • Antihistamines
  • Local Anaesthetics
  • Immunosuppressants
  • Others

By Disease:

  • Atopic Dermatitis
  • Allergic Contact Dermatitis
  • Urticaria
  • Psoriasis

By Route of Administration:

  • Oral
  • Parenteral
  • Topical

By Distribution Channel:

  • Hospital Pharmacies
  • Drug Stores
  • Retail Pharmacies
  • Online Stores

By Region:

  • North America
  • Latin America
  • Europe
  • South Asia
  • East Asia
  • Oceania
  • The Middle East & Africa (MEA)

Frequently Asked Questions

How Much is the Antipruritic Market Currently Worth?

The global antipruritic market is worth USD 10.9 billion in 2024.

What is the Sales Forecast for Antipruritic through 2034?

The market is expected to reach USD 16.2 billion by the end of 2034 at a CAGR of 4.2%.

What are the Trends Driving the Global Antipruritic Market?

The growing geriatric population, rising burden of skin diseases, and rising R&D on novel biopharmaceuticals.

Which Region is Developing at a Higher CAGR in the Global Antipruritic Market?

The antipruritic market in East Asia and Latin America is expanding at 4.7% CAGR.

What is the Projection for the Antipruritic Market in Europe?

Europe is projected to develop with a CAGR of 4.2% during the forecast period.

Which are the Top Five Countries Driving Demand for Antipruritic?

The United States, the United Kingdom, China, Japan, and Germany are the top five countries in the market.

Who are the Key Manufacturers in the Antipruritic Market?

AbbVie Inc., Allergan, Merck & Co., Inc., and Pfizer Inc. are some key players in the antipruritics industry.

What were the last five years' CAGR for the Antipruritic Market?

From 2019 to 2023, the antipruritics market expanded at a 4.1% CAGR.

Table of Content
  • 1. Executive Summary
  • 2. Market Overview
  • 3. Key Market Trends
  • 4. Key Success Factors
  • 5. Market Background
  • 6. Global Market Demand (in Value or Size in USD Million) Analysis 2017 to 2022 and Forecast, 2023 to 2033
  • 7. Global Market Analysis 2017 to 2022 and Forecast 2023 to 2033, By Drug
    • 7.1. Corticosteroids
    • 7.2. Antihistamines
    • 7.3. Local Anesthetics
    • 7.4. Immunosuppressants
    • 7.5. Others
  • 8. Global Market Analysis 2017 to 2022 and Forecast 2023 to 2033, By Disease
    • 8.1. Atopic Dermatitis
    • 8.2. Allergic Contact Dermatitis
    • 8.3. Urticaria
    • 8.4. Psoriasis
  • 9. Global Market Analysis 2017 to 2022 and Forecast 2023 to 2033, By Route of Administration
    • 9.1. Oral
    • 9.2. Parenteral
    • 9.3. Topical
  • 10. Global Market Analysis 2017 to 2022 and Forecast 2023 to 2033, By Distribution Channel
    • 10.1. Hospital Pharmacies
    • 10.2. Drug Stores
    • 10.3. Retail Pharmacies
    • 10.4. Online Stores
  • 11. Global Market Analysis 2017 to 2022 and Forecast 2023 to 2033, By Region
    • 11.1. North America
    • 11.2. Latin America
    • 11.3. Europe
    • 11.4. East Asia
    • 11.5. South Asia
    • 11.6. Oceania
    • 11.7. Middle East and Africa
  • 12. North America Market Analysis 2017 to 2022 and Forecast 2023 to 2033
  • 13. Latin America Market Analysis 2017 to 2022 and Forecast 2023 to 2033
  • 14. Europe Market Analysis 2017 to 2022 and Forecast 2023 to 2033
  • 15. East Asia Market Analysis 2017 to 2022 and Forecast 2023 to 2033
  • 16. South Asia Market Analysis 2017 to 2022 and Forecast 2023 to 2033
  • 17. Oceania Market Analysis 2017 to 2022 and Forecast 2023 to 2033
  • 18. Middle East and Africa (MEA) Market Analysis 2017 to 2022 and Forecast 2023 to 2033
  • 19. Market Structure Analysis
  • 20. Competition Analysis
    • 20.1. AbbVie Inc.
    • 20.2. Allergan, Merck & Co., Inc.
    • 20.3. Amgen Inc.
    • 20.4. Pfizer Inc.
    • 20.5. Cara Therapeutics
    • 20.6. Enteris BioPharma
    • 20.7. NeRRe Therapeutics
    • 20.8. Menlo Therapeutics
    • 20.9. XBiotech Inc.
    • 20.10. Ipsen Pharma
    • 20.11. Eledon Pharmaceuticals, Inc.
    • 20.12. Amorepacific
    • 20.13. RDD Pharma, Ltd
    • 20.14. Novartis AG
    • 20.15. AstraZeneca
    • 20.16. Sanofi
    • 20.17. Sun Pharmaceutical Industries Ltd.
    • 20.18. Teva Pharmaceutical Industries Ltd.
    • 20.19. Takeda Pharmaceutical Company Limited
    • 20.20. Cipla Ltd.
  • 21. Assumptions and Acronyms Used
  • 22. Research Methodology
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