Reports

- Global Locations -

Headquarters

Future Market Insights, Inc.

Christiana Corporate, 200
Continental Drive, Suite 401,
Newark, Delaware - 19713,
United States

T: +1-347-918-3531

Americas

Future Market Insights, Inc.

616 Corporate Way, Suite 2-9018,
Valley Cottage, NY 10989, United States

MEA

Future Market Insights

1602-6 Jumeirah Bay X2 Tower, Plot No: JLT-PH2-X2A,
Jumeirah Lakes Towers, Dubai,
United Arab Emirates

Europe

Future Market Insights

3rd Floor, 207 Regent Street,
W1B 3HH London
United Kingdom

T: + 44 (0) 20 8123 9659

Asia Pacific

Future Market Insights

IndiaLand Global Tech Park, Unit UG-1, Behind Grand HighStreet, Phase 1, Hinjawadi, MH, Pune – 411057, India

Analytical Study of Dietary Supplement in Japan from 2023 to 2033

Sales of dietary supplement in Japan are estimated to rise at a 6.2% CAGR through 2033. The overall demand for dietary supplement in Japan is likely to surge considerably, crossing a valuation of US$ 1,266.09 million in 2023. By 2033, sales projections for dietary supplement in Japan indicate attaining a valuation of US$ 2,310.30 million.

Attributes Details
Industry Size in Japanin 2023 US$ 1,266.09 million
Expected Industry Size of Japan by 2033 US$ 2,310.30 million
Forecasted CAGR between 2023 to 2033 6.2%

Don't pay for what you don't need

Customize your report by selecting specific countries or regions and save 30%!

Key Trends to Boost Sales through 2033

  • Tapping into the growing interest in mental wellness, there has been a rise in the market for nootropic supplements. These products, intended to improve concentration, memory, and general cognitive function, could develop into a lucrative niche.
  • A deliberate shift is underway to include probiotics and prebiotics in dietary supplement in response to the global trend emphasizing gut health. This presents a significant opportunity for sales growth as it corresponds with increased consumer consciousness about digestive health.
  • There has been a surge in the popularity of wellness and health, with individuals being more aware of their lifestyle and food choices. The use of dietary supplement to improve nutrition and encourage greater health is a common practice in this movement.
  • Supplements that improve skin health, hair development, and general beauty could experience an increase in demand that coincides with the worldwide trend. Collagen supplements, for example, have gained popularity in Japan due to their alleged benefits for skin elasticity.
  • Consumers are becoming more ecologically sensitive, which could mean an increase in demand for dietary supplement that emphasize sustainability, ethical sourcing, and clean-label components.

Key Insights - Highlights on the Emerging Opportunities in the Japan Dietary Supplement Industry

  • Innovative delivery forms, such as soluble strips, gummies, or liquid mixtures, can help organizations stand out. Consumer preferences for easy and appealing supplement forms provide an opportunity for firms to differentiate their products in the market.
  • Supplements meant to improve cognitive function, memory, and attention have the potential to target students and professionals. Addressing the needs of individuals seeking to improve mental performance in academic and professional contexts is a promising avenue.
  • Subscription-based supplement distribution schemes emerge as a strategy to enhance customer convenience and loyalty. This approach not only ensures a consistent revenue stream but also enables firms to maintain direct interaction with their customer base.
  • Smart packaging, incorporating QR codes for extensive product information, usage instructions, and authenticity verification, can substantially boost customer confidence. This technologically driven approach is in line with the digital era and offers a distinct selling characteristic.
  • For businesses targeting the fitness-conscious crowd, providing supplements specifically developed for post-workout recovery presents a valuable opportunity. These products, enriched with ingredients promoting muscle repair, reducing inflammation, and replenishing nutrients, cater to the needs of health-conscious consumers.
Nandini Roy Choudhury
Nandini Roy Choudhury

Principal Consultant

Talk to Analyst

Find your sweet spots for generating winning opportunities in this market.

Comparative View of Adjacent Dietary Supplement in Key Markets

The table showcases a comparative overview of dietary supplement and its respective adoption rates in Japan, Korea, and at the global level. In Japan, with the rise of the fitness culture, there is likely a greater demand for nutritional supplements aimed at athletes and fitness enthusiasts. This can involve products designed to aid in muscle rehabilitation, improve performance, and fulfill the nutritional requirements of athletes.

In Korea, a distinct trend is the personalization of dietary supplement to meet specific health needs. This technique is gaining momentum as customers seek individualized solutions to particular health goals based on criteria such as age, gender, health condition, and genetic predispositions.

Globally, the industry is undergoing an evolutionary shift toward the seamless incorporation of functional ingredients into food and beverage products. Manufacturers are profiting from the notion of "food as medicine," aiming to bring easy-to-integrate dietary supplement into consumers' regular nutrition regimens.

Industry Analysis of Dietary Supplement in Japan:

Attributes Industry Analysis of Dietary Supplement in Japan
Japan CAGR between 2023 and 2033 6.2%
Industry Size of Japan in 2023 US$ 1,266.09 million
Key Trend in Japan Growing demand for fitness and sports nutrition
Key Challenge Aging population and health concerns

Demand for Dietary Supplement in Korea:

Attributes Demand for Dietary Supplement in Korea
CAGR (2023 to 2033) 10.4%
Valuation (2023) US$ 1,561.41 million
Key Trend Rising demand for personalized nutrition solutions
Key Challenge Increasing competition in the industry

Opportunity Assessment for the Global Dietary Supplement Industry:

Attributes Opportunity Assessment for the Global Dietary Supplement Industry
CAGR (2023 to 2033) 9.1%
Valuation (2023) US$ 68.20 billion
Key Trend Rising integration in food and beverages
Key Challenge Distribution challenges remain high

Category-wise insights

Growing Popularity of Plant-based Diets Surges Demand for Amino Acids as Ingredients

Top Ingredient for Dietary Supplement in Japan Amino Acids
Total Value Share (2023) 41.70%

With the growing popularity of vegan and plant-based diets, there is an increased need for supplements that deliver critical amino acids that may be lacking in plant-based meals. Amino acid supplements can assist people who live plant-based lifestyles in filling nutritional shortages. Some amino acids aid in maintaining digestive health and developing good gut bacteria. As people become more aware of the importance of gut health, amino acids can be incorporated into supplements that promote digestive health. Continuous research and innovation in supplement formulations can result in the creation of solutions with improved bioavailability and tailored amino acid delivery. Such developments are likely to increase the appeal of amino acid-based supplements.

Easy Consumption Aspects Boost Demand for Soft Gel/Pills

Leading Form for Dietary Supplement in Japan Soft Gel/Pills
Total Value Share (2023) 57.80%

Since soft gels and tablets are portable, they are ideal for on-the-go ingestion. This aligns with the hectic lifestyles of many consumers who prefer items that they can easily transport wherever they go. Soft gels enable the encapsulation of a wide variety of components, such as oils, vitamins, and herbal extracts. Because of this adaptability, producers can offer a wide range of supplements in this convenient form. There is potential to design supplements targeted at individuals with specific medical issues by collaborating with healthcare providers. This strategy requires extensive research, adherence to rules, and collaboration with the healthcare industry.

Get the data you need at a Fraction of the cost

Personalize your report by choosing insights you need
and save 40%!

Strategies for Key Players to Tap into Potential Growth Opportunities

  • Invest in robust digital marketing techniques that leverage e-commerce platforms and social media to enhance online presence.
  • Provide personalized supplement recommendations based on individual health profiles and preferences using data analytics.
  • Identify and capitalize on supplement niches in the marketplace, such as cosmetic or cognitive health products.
  • Launch comprehensive consumer education efforts that offer clear product information and usage recommendations to instill confidence.
  • Recognize and adjust marketing techniques to align with Japanese cultural values and customer behavior.

Recent Developments in Dietary Supplement in Japan

  • In April 2023, a prominent Japanese oyster brand entered the supplement industry with the launch of zinc-rich tablets produced from oyster ingredients, targeting beauty- and health-conscious women. The "8th Sea Oyster Supplement" was developed under the supervision of Professor Hitoshi Shirakawa of Tohoku University's Graduate School of Agricultural Science, specializing in nutritional science and molecular biology.
  • In October 2022, Neopharma Japan introduced "WIZALA," the world's first 5-ALA supplement for puppies and kittens.

Some of the Key Players Offering Dietary Supplement in Japan

  • Takeda Pharmaceutical Company Limited
  • Otsuka Pharmaceutical Co., Ltd.
  • Daiichi Sankyo Company, Limited
  • Eisai Co., Ltd.
  • Meiji Holdings Co., Ltd.

Scope of the Report

Attribute Details
Estimated Industry Size in 2023 US$ 1,266.09 million
Projected Industry Size by 2033 US$ 2,310.30 million
Anticipated CAGR between 2023 to 2033 6.2% CAGR
Historical Analysis of Demand for Dietary Supplement in Japan 2018 to 2022
Demand Forecast for Dietary Supplement in Japan 2023 to 2033
Report Coverage Industry Size, Industry Trends, Analysis of key factors influencing Dietary Supplement adoption in Japan, Insights on Global Players and their Industry Strategy in Japan, Ecosystem Analysis of Local and Regional Japan Manufacturers
Key Cities Analyzed While Studying Opportunities in Dietary Supplement in Japan
  • Kanto
  • Chubu
  • Kinki
  • Kyushu & Okinawa
  • Tohoku
  • Rest of Japan
Key Companies Profiled
  • Takeda Pharmaceutical Company Limited
  • Otsuka Pharmaceutical Co., Ltd.
  • Daiichi Sankyo Company, Limited
  • Eisai Co., Ltd.
  • Meiji Holdings Co., Ltd.

Key Segments

By Form:

  • Soft Gel or Capsules
    • Confectionery Products
      • Gummies
      • Chews
      • Others
    • Pharmaceutical Products
      • Chewable Pills and Pills
      • Soft Gel
  • Powder
  • Liquid

By Ingredient:

  • Vitamins & Minerals
  • Amino Acids
  • Botanical Supplements
  • Others

By End Use:

  • Men
  • Women
  • Senior Citizen
  • Others

By Application:

  • Weight Loss
  • Sports Nutrients
  • General Well Being
  • Immune Health and Digestive Health
  • Bone and Joint Health
  • Heart Health
  • Others

By Distribution Channel:

  • Pharmacies Drug Store
  • Health & Beauty Stores
  • Others

By City:

  • Kanto
  • Chubu
  • Kinki
  • Kyushu & Okinawa
  • Tohoku
  • Rest of Japan

Frequently Asked Questions

How Rapidly is the Demand for Dietary Supplement in Japan Growing? 

The expected CAGR until 2033 stands at 6.2%. 

What is the Demand Outlook for Dietary Supplement in Japan? 

The demand for dietary supplement in Japan is projected to reach US$ 2,310.30 million by 2033. 

Which Trends Influence the Demand for Dietary Supplement in Japan?

Health and wellness trends highly influence product demand in Japan.

What Strategies are used by Dietary Supplement Manufacturers in Japan?

Dietary supplement manufacturers emphasize continual advancements in product offerings.

What is the Leading Ingredient for Dietary Supplement in Japan?

Amino acids are highly popular in dietary supplement in Japan.

Table of Content

1. Executive Summary

    1.1. Market Outlook

    1.2. Demand-side Trends

    1.3. Supply-side Trends

    1.4. Analysis and Recommendations

2. Market Overview

    2.1. Market Coverage / Taxonomy

    2.2. Market Definition / Scope / Limitations

3. Market Background

    3.1. Market Dynamics

        3.1.1. Drivers

        3.1.2. Restraints

        3.1.3. Opportunity

        3.1.4. Trends

    3.2. Scenario Forecast

        3.2.1. Demand in Optimistic Scenario

        3.2.2. Demand in Likely Scenario

        3.2.3. Demand in Conservative Scenario

    3.3. Opportunity Map Analysis

    3.4. Product Life Cycle Analysis

    3.5. Supply Chain Analysis

        3.5.1. Supply Side Participants and their Roles

            3.5.1.1. Producers

            3.5.1.2. Mid-Level Participants (Traders/ Agents/ Brokers)

            3.5.1.3. Wholesalers and Distributors

        3.5.2. Value Added and Value Created at Node in the Supply Chain

        3.5.3. List of Raw Material Suppliers

        3.5.4. List of Existing and Potential Buyer’s

    3.6. Investment Feasibility Matrix

    3.7. Value Chain Analysis

        3.7.1. Profit Margin Analysis

        3.7.2. Wholesalers and Distributors

        3.7.3. Retailers

    3.8. PESTLE and Porter’s Analysis

    3.9. Regulatory Landscape

        3.9.1. By Key Regions

    3.10. Regional Parent Market Outlook

    3.11. Production and Consumption Statistics

    3.12. Import and Export Statistics

4. Industry Analysis and Outlook 2018 to 2022 and Forecast, 2023 to 2033

    4.1. Historical Market Size Value (US$ Million) & Volume (Units pack) Analysis, 2018 to 2022

    4.2. Current and Future Market Size Value (US$ Million) & Volume (Units pack) Projections, 2023 to 2033

        4.2.1. Y-o-Y Growth Trend Analysis

        4.2.2. Absolute $ Opportunity Analysis

5. Industry Analysis and Outlook 2018 to 2022 and Forecast 2023 to 2033, By Ingredients

    5.1. Introduction / Key Findings

    5.2. Historical Market Size Value (US$ Million) & Volume (Units pack) Analysis By Ingredients , 2018 to 2022

    5.3. Current and Future Market Size Value (US$ Million) & Volume (Units pack) Analysis and Forecast By Ingredients , 2023 to 2033

        5.3.1. Amino Acid

        5.3.2. Animal Extract

        5.3.3. Botanical Extract

        5.3.4. Mineral

        5.3.5. Nucleotide

        5.3.6. Omega 3

        5.3.7. Probiotics

        5.3.8. Protein

        5.3.9. Sugar

        5.3.10. Vegetable Oil & Powder

        5.3.11. Vitamin

        5.3.12. Yeast Extract

    5.4. Y-o-Y Growth Trend Analysis By Ingredients , 2018 to 2022

    5.5. Absolute $ Opportunity Analysis By Ingredients , 2023 to 2033

6. Industry Analysis and Outlook 2018 to 2022 and Forecast 2023 to 2033, By Form

    6.1. Introduction / Key Findings

    6.2. Historical Market Size Value (US$ Million) & Volume (Units pack) Analysis By Form, 2018 to 2022

    6.3. Current and Future Market Size Value (US$ Million) & Volume (Units pack) Analysis and Forecast By Form, 2023 to 2033

        6.3.1. Soft Gel/Pills

            6.3.1.1. Confectionery Products

            6.3.1.2. Pharmaceuticals Products

        6.3.2. Powder

        6.3.3. Liquid

    6.4. Y-o-Y Growth Trend Analysis By Form, 2018 to 2022

    6.5. Absolute $ Opportunity Analysis By Form, 2023 to 2033

7. Industry Analysis and Outlook 2018 to 2022 and Forecast 2023 to 2033, By Application 

    7.1. Introduction / Key Findings

    7.2. Historical Market Size Value (US$ Million) & Volume (Units pack) Analysis By Application , 2018 to 2022

    7.3. Current and Future Market Size Value (US$ Million) & Volume (Units pack) Analysis and Forecast By Application , 2023 to 2033

        7.3.1. Weight Loss

        7.3.2. Sports Nutrition’s

        7.3.3. General Well-Beings

        7.3.4. Immune & Digestive Health

        7.3.5. Bone & Joint Health

        7.3.6. Heart Health

        7.3.7. Others Specific Requirements (Supplements, Anti -Allergies & EyeHealth)

    7.4. Y-o-Y Growth Trend Analysis By Application , 2018 to 2022

    7.5. Absolute $ Opportunity Analysis By Application , 2023 to 2033

8. Industry Analysis and Outlook 2018 to 2022 and Forecast 2023 to 2033, By Region

    8.1. Introduction

    8.2. Historical Market Size Value (US$ Million) & Volume (Units pack) Analysis By Region, 2018 to 2022

    8.3. Current Market Size Value (US$ Million) & Volume (Units pack) Analysis and Forecast By Region, 2023 to 2033

        8.3.1. Kanto

        8.3.2. Chubu

        8.3.3. Kinki

        8.3.4. Kyushu & Okinawa

        8.3.5. Tohoku

        8.3.6. Rest of Japan

    8.4. Market Attractiveness Analysis By Region

9. Kanto Industry Analysis and Outlook 2018 to 2022 and Forecast 2023 to 2033

    9.1. Historical Market Size Value (US$ Million) & Volume (Units pack) Trend Analysis By Market Taxonomy, 2018 to 2022

    9.2. Market Size Value (US$ Million) & Volume (Units pack) Forecast By Market Taxonomy, 2023 to 2033

        9.2.1. By Ingredients

        9.2.2. By Form

        9.2.3. By Application

    9.3. Market Attractiveness Analysis

        9.3.1. By Ingredients

        9.3.2. By Form

        9.3.3. By Application

    9.4. Key Takeaways

10. Chubu Industry Analysis and Outlook 2018 to 2022 and Forecast 2023 to 2033

    10.1. Historical Market Size Value (US$ Million) & Volume (Units pack) Trend Analysis By Market Taxonomy, 2018 to 2022

    10.2. Market Size Value (US$ Million) & Volume (Units pack) Forecast By Market Taxonomy, 2023 to 2033

        10.2.1. By Ingredients

        10.2.2. By Form

        10.2.3. By Application

    10.3. Market Attractiveness Analysis

        10.3.1. By Ingredients

        10.3.2. By Form

        10.3.3. By Application

    10.4. Key Takeaways

11. Kinki Industry Analysis and Outlook 2018 to 2022 and Forecast 2023 to 2033

    11.1. Historical Market Size Value (US$ Million) & Volume (Units pack) Trend Analysis By Market Taxonomy, 2018 to 2022

    11.2. Market Size Value (US$ Million) & Volume (Units pack) Forecast By Market Taxonomy, 2023 to 2033

        11.2.1. By Ingredients

        11.2.2. By Form

        11.2.3. By Application

    11.3. Market Attractiveness Analysis

        11.3.1. By Ingredients

        11.3.2. By Form

        11.3.3. By Application

    11.4. Key Takeaways

12. Kyushu & Okinawa Industry Analysis and Outlook 2018 to 2022 and Forecast 2023 to 2033

    12.1. Historical Market Size Value (US$ Million) & Volume (Units pack) Trend Analysis By Market Taxonomy, 2018 to 2022

    12.2. Market Size Value (US$ Million) & Volume (Units pack) Forecast By Market Taxonomy, 2023 to 2033

        12.2.1. By Ingredients

        12.2.2. By Form

        12.2.3. By Application

    12.3. Market Attractiveness Analysis

        12.3.1. By Ingredients

        12.3.2. By Form

        12.3.3. By Application

    12.4. Key Takeaways

13. Tohoku Industry Analysis and Outlook 2018 to 2022 and Forecast 2023 to 2033

    13.1. Historical Market Size Value (US$ Million) & Volume (Units pack) Trend Analysis By Market Taxonomy, 2018 to 2022

    13.2. Market Size Value (US$ Million) & Volume (Units pack) Forecast By Market Taxonomy, 2023 to 2033

        13.2.1. By Ingredients

        13.2.2. By Form

        13.2.3. By Application

    13.3. Market Attractiveness Analysis

        13.3.1. By Ingredients

        13.3.2. By Form

        13.3.3. By Application

    13.4. Key Takeaways

14. Rest of Industry Analysis and Outlook 2018 to 2022 and Forecast 2023 to 2033

    14.1. Historical Market Size Value (US$ Million) & Volume (Units pack) Trend Analysis By Market Taxonomy, 2018 to 2022

    14.2. Market Size Value (US$ Million) & Volume (Units pack) Forecast By Market Taxonomy, 2023 to 2033

        14.2.1. By Ingredients

        14.2.2. By Form

        14.2.3. By Application

    14.3. Market Attractiveness Analysis

        14.3.1. By Ingredients

        14.3.2. By Form

        14.3.3. By Application

    14.4. Key Takeaways

15. Market Structure Analysis

    15.1. Competition Dashboard

    15.2. Competition Benchmarking

    15.3. Market Share Analysis of Top Players

        15.3.1. By Regional

        15.3.2. By Ingredients

        15.3.3. By Form

        15.3.4. By Application

16. Competition Analysis

    16.1. Competition Deep Dive

        16.1.1. Amway Corp.

            16.1.1.1. Overview

            16.1.1.2. Product Portfolio

            16.1.1.3. Profitability by Market Segments

            16.1.1.4. Sales Footprint

            16.1.1.5. Strategy Overview

                16.1.1.5.1. Marketing Strategy

                16.1.1.5.2. Product Strategy

                16.1.1.5.3. Channel Strategy

        16.1.2. Glanbia PLC

            16.1.2.1. Overview

            16.1.2.2. Product Portfolio

            16.1.2.3. Profitability by Market Segments

            16.1.2.4. Sales Footprint

            16.1.2.5. Strategy Overview

                16.1.2.5.1. Marketing Strategy

                16.1.2.5.2. Product Strategy

                16.1.2.5.3. Channel Strategy

        16.1.3. Abbott

            16.1.3.1. Overview

            16.1.3.2. Product Portfolio

            16.1.3.3. Profitability by Market Segments

            16.1.3.4. Sales Footprint

            16.1.3.5. Strategy Overview

                16.1.3.5.1. Marketing Strategy

                16.1.3.5.2. Product Strategy

                16.1.3.5.3. Channel Strategy

        16.1.4. Bayer AG

            16.1.4.1. Overview

            16.1.4.2. Product Portfolio

            16.1.4.3. Profitability by Market Segments

            16.1.4.4. Sales Footprint

            16.1.4.5. Strategy Overview

                16.1.4.5.1. Marketing Strategy

                16.1.4.5.2. Product Strategy

                16.1.4.5.3. Channel Strategy

        16.1.5. Pfizer Inc.

            16.1.5.1. Overview

            16.1.5.2. Product Portfolio

            16.1.5.3. Profitability by Market Segments

            16.1.5.4. Sales Footprint

            16.1.5.5. Strategy Overview

                16.1.5.5.1. Marketing Strategy

                16.1.5.5.2. Product Strategy

                16.1.5.5.3. Channel Strategy

        16.1.6. ADM

            16.1.6.1. Overview

            16.1.6.2. Product Portfolio

            16.1.6.3. Profitability by Market Segments

            16.1.6.4. Sales Footprint

            16.1.6.5. Strategy Overview

                16.1.6.5.1. Marketing Strategy

                16.1.6.5.2. Product Strategy

                16.1.6.5.3. Channel Strategy

        16.1.7. Nu Skin Enterprises, Inc.

            16.1.7.1. Overview

            16.1.7.2. Product Portfolio

            16.1.7.3. Profitability by Market Segments

            16.1.7.4. Sales Footprint

            16.1.7.5. Strategy Overview

                16.1.7.5.1. Marketing Strategy

                16.1.7.5.2. Product Strategy

                16.1.7.5.3. Channel Strategy

        16.1.8. GlaxoSmithKline plc

            16.1.8.1. Overview

            16.1.8.2. Product Portfolio

            16.1.8.3. Profitability by Market Segments

            16.1.8.4. Sales Footprint

            16.1.8.5. Strategy Overview

                16.1.8.5.1. Marketing Strategy

                16.1.8.5.2. Product Strategy

                16.1.8.5.3. Channel Strategy

        16.1.9. Bionova

            16.1.9.1. Overview

            16.1.9.2. Product Portfolio

            16.1.9.3. Profitability by Market Segments

            16.1.9.4. Sales Footprint

            16.1.9.5. Strategy Overview

                16.1.9.5.1. Marketing Strategy

                16.1.9.5.2. Product Strategy

                16.1.9.5.3. Channel Strategy

        16.1.10. Ayanda

            16.1.10.1. Overview

            16.1.10.2. Product Portfolio

            16.1.10.3. Profitability by Market Segments

            16.1.10.4. Sales Footprint

            16.1.10.5. Strategy Overview

                16.1.10.5.1. Marketing Strategy

                16.1.10.5.2. Product Strategy

                16.1.10.5.3. Channel Strategy

        16.1.11. Arkopharma

            16.1.11.1. Overview

            16.1.11.2. Product Portfolio

            16.1.11.3. Profitability by Market Segments

            16.1.11.4. Sales Footprint

            16.1.11.5. Strategy Overview

                16.1.11.5.1. Marketing Strategy

                16.1.11.5.2. Product Strategy

                16.1.11.5.3. Channel Strategy

17. Assumptions & Acronyms Used

18. Research Methodology

Recommendations

Food and Beverage

Insoluble Dietary Fiber Market

Published : April 2024

Food and Beverage

Dietary Fiber Market

Published : January 2024

Food and Beverage

Dietary Supplement Market

Published : January 2024

Explore Food and Beverage Insights

View Reports

Demand and Trends Analysis of Dietary Supplements in Japan