Atherosclerosis Market Snapshot (2023 to 2033)

The atherosclerosis market is anticipated to attain a valuation of USD 59,514.3 million by 2033, capturing a CAGR of 2.8% between 2023 and 2033 from a current value of USD 45,165.6 million in 2023. The rise in the prevalence of cardiovascular disorders is a significant factor driving market growth.

Data Points Key Statistics
Expected Market Value (2023) USD 45,165.6 million
Anticipated Forecast Value (2033) USD 59,514.3 million
Projected Growth Rate (2023 to 2033) 2.8% CAGR

Atherosclerosis is the shrinking of a vein caused by plaque accumulation. Atherosclerosis is a kind of arteriosclerosis (stiffening or solidifying of the artery walls). The sickness disrupts the flow of blood throughout the body, posing significant cardiovascular complications.

Atherosclerosis starts when the endothelium is damaged, allowing LDL cholesterol to accumulate in the arterial wall. To clean up the cholesterol, the body sends macrophage white platelets.

However, the cells occasionally halt at the impacted spot. After a while, this resulted in plaque formation, which was composed of bad cholesterol (LDL cholesterol) and macrophage white platelets. The plaque obstructs the corridor, disrupting the flow of blood throughout the body. This may result in blood clusters, which can lead to life-threatening diseases such as heart attack, stroke, and other cardiovascular disorders.

Aside from age, the following factors increase the risk of atherosclerosis: high blood pressure, high cholesterol, diabetes, obesity, smoking or other tobacco use, family history of early heart disease, lack of exercise, and a poor diet.

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Atherosclerosis Demand Analysis (2018 to 2022) Vs. Market Outlook (2023 to 2033)

The global demand for atherosclerosis treatment is projected to increase at a CAGR of 2.8% during the forecast period between 2023 and 2033, reaching a total of USD 59,514.3 million in 2033, according to a report from Future Market Insights (FMI). From 2018 to 2022, sales witnessed significant growth, registering a CAGR of 1.8%.

The rise in heart attacks caused by atherosclerosis or coronary heart disease is expected to drive up demand for atherosclerosis treatment products. The aging population is expected to drive demand during the forecast period.

According to the CDC (Centres for Disease Control and Prevention), coronary illness accounts for approximately 610,000 deaths per year in the United States, accounting for roughly one out of every four reported deaths. Coronary disease is the most well-known type of coronary disease, killing over 370,000 people each year.

This increase in the baby boomer population is expected to increase in atherosclerosis patients and, as a result, demand for treatment over the forecast period.

The market for atherosclerosis is growing due to increased prevalence, obesity, sedentary lifestyle, hypertension, dyslipidemia, particularly a decrease in high thickness cholesterol (HDL-C), and elevated cholesterol slim down.

Statins, angiotensin-converting enzyme (ACE) inhibitors, beta-blockers (BB), antiplatelets, calcium channel blockers (CCBs), and nitrates are among the medications used to treat atherosclerosis.

Yosprala (headache medicine and omeprazole), Praluent (alirocumab), Dalcetrapib (RG1658), Vorapaxar (SCH 530348), Canakinumab (ACZ885), Varespladib (A 002), Aliskiren, Generx, Xarelto (rivaroxaban), Anacetrapib (MK0859), and others are expected to be launched during the forecasting period.

Which are Some Prominent Drivers of the Atherosclerosis Market?

An Expanding Geriatric Population Base and Subsequent Rise in Cardiac Anomalies

The worldwide atherosclerosis industry is poised to increase as the geriatric population grows and the incidence rate of heart attacks caused by coronary heart disease or atherosclerosis rises. Furthermore, the availability of new treatment approaches (both branded and generic) is a key driver of the global atherosclerosis therapeutics market.

According to the Centres for Disease Control and Prevention (CDC), approximately 610 000 people in the United States died as a result of heart disease, accounting for nearly one out of every four deaths. Coronary artery disease is the most common type of heart disease, accounting for around 370,000 deaths each year. These factors are expected to boost the global market for atherosclerosis.

Increasing Prevalence of Obesity and High Cholesterol to Widen Growth Prospects

Rising obesity and high cholesterol rates are expected to boost market growth by increasing the risk of atherosclerosis. According to the World Health Organization, around 40 million children under five were overweight or obese in 2018. (WHO).

Increased consumption of high-fat, high-sugar foods, as well as an increase in physical immobility due to the increasingly inactive nature of many types of work, changing modes of transportation, and increasing urbanization, all contribute to high cholesterol rates, resulting in rapid market growth.

Furthermore, rising awareness-raising initiatives by public and private organizations are expected to expand the atherosclerosis market. Furthermore, the sedentary lifestyle of people, such as high alcohol consumption and smoking addiction, is projected to result in the expansion of the atherosclerosis market. The rising level of disposable income and the high prevalence of high blood pressure are expected to drive the industry's growth rate during the forecast period.

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What Are the Challenges Faced by the Atherosclerosis Market?

Absence of Definitive Therapy to Stymie the Market Growth

New competitors in the atherosclerosis market have demonstrated increased adequacy and security profiles, as well as a reduction in CHD risk factors. Atherosclerosis, also known as coronary artery disease, has two treatment options: coronary artery bypass grafting (CABG) and angioplasty.

The CAD death rate is relatively high when compared to other diseases caused by coronary events associated with CAD, such as myocardial infections (MI), angina, and strokes. As a result, the antidote to such situations remains an unexplored area of research and development for pharmaceutical companies seeking to bring breakthrough drugs to market.

However, the absence of definitive therapy, side effects and limited efficacy of current medications, and reliance on symptom-based treatment in certain situations are likely to hinder revenue growth in the atherosclerosis market throughout the forecast period.

Moreover, the high cost of the treatment is expected to hamper the market's growth rate. The atherosclerosis market is estimated to be challenged by a lack of skilled professionals and a dearth of healthcare infrastructure in developing economies. Furthermore, strict regulatory policies and a lack of public awareness might restrain and impede market growth during the forecast period.

Region-wise Insights

How is the North American Atherosclerosis Market Shaping Up?

High Prevalence of Cardiovascular Diseases Creating Opportunities for Atherosclerosis Treatment Providers

Country Forecast CAGR % (2023 to 2033)
North America’s Market Share % (2022) 37.8%
The United States Market Share % (2022) 32.4%

The North American atherosclerosis market is slated to acquire a market share of 37.8% in 2022. The presence of key players, the high prevalence of cardiovascular diseases and atherosclerosis, and the established healthcare infrastructure are some key factors responsible for the market's large share. Furthermore, beneficial government initiatives and an increase in the number of research collaborations are expected to drive market growth.

Because of supportive healthcare policies, several patients, and a developed healthcare market, the United States have the largest share in this region. Around 647,000 Americans die annually from heart disease, accounting for one in every four deaths.

Every year, the United States spends around USD 219 billion on heart disease. According to statistics, this country's increasing patient pool and disposable revenue drive regional market growth.

Why is Asia Pacific considering the Fast-growing Market for Atherosclerosis?

Increasing Geriatric Population Favoring Market Growth

Country Forecast CAGR % (2023 to 2033)
China 3.9%
India 4.4%

The Asia Pacific is anticipated to increase during the forecast period due to an increasing geriatric population and rising disposable income levels in this region.

Furthermore, the expansion of healthcare infrastructure and rising government initiatives are expected to accelerate the market's growth rate in this region. Thus, the Asia Pacific is expected to hold 25% of the market share for the atherosclerosis market in the forecast period.

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Category-wise Insights

Which Therapy Segment is Gaining Traction in the Atherosclerosis Market?

Cholesterol-lowering Medications to Remain Most Sought After

Segment Market Share % (2022)
Cholesterol Lowering Medication 44.7%

Statins and fibrates are examples of cholesterol-lowering medications. The segment's dominance is attributed to the rising prevalence of cardiovascular disease, high cholesterol, and obesity worldwide. According to the World Health Organization, 40 million children under the age of five were overweight or obese in 2018.

A higher intake of energy-dense foods high in fat and sugars, as well as an increase in physical immobility due to the increasingly inactive nature of many types of work, changing modes of transportation, and increasing urbanization, are factors driving high cholesterol rates and, ultimately, boosting segment growth.

In addition, the approval of new cholesterol-lowering medicines is boosting segment growth. For example, the drugs alirocumab (Praluent) and evolocumab (Repatha) belong to a new class of drugs known as PCSK9 inhibitors, which reduce harmful LDL cholesterol levels by more than 50%. Novel treatment drugs of this type boost segment growth. The growing patient pool and increased approvals for new medicines boost segment growth.

Which is the Leading Distribution Channel of the Atherosclerosis Market?

Retail Pharmacies are expected to Continue to Be a Beneficial Distribution Channel

Segment Market Share % (2022)
Retail Pharmacies 38.2%

As per Future Market Insights (FMI), the retail pharmacies segment is expected to become the primary point-of-sale channel for atherosclerosis as they expand to even the most remote locations, making it easier for consumers to present prescriptions and purchase drugs.

Furthermore, retail pharmacists provide more consultative services regarding drug administration routes and potential side effects. Retail pharmacies carry a variety of brands, making them a good place for patients to shop. Hospital pharmacists, on the other hand, operate in a more clinic-oriented manner, having frequent contact with doctors and nurses, and they manage their inventories with only specific brands.

Start-ups for Atherosclerosis Market

Key startup players in the atherosclerosis market:

  • Moderna is a leader in the development of a new class of drugs based on messenger RNA (mRNA). This novel drug platform is based on the discovery that modified mRNA can direct the body's cellular machinery to produce nearly any protein of interest, ranging from native proteins to antibodies and completely novel protein constructs with therapeutic activity inside and outside cells.
  • Humacyte creates novel human tissue-based investigational products for regenerative medicine and vascular surgery. The company's proprietary technology platform is used to isolate and grow stable, ‘off-the-shelf’ investigational human tissue replacements that, if approved, could be tailored to pre-designed clinical and commercial specifications.
  • CardioDx is a Redwood City, California-based cardiovascular genomic diagnostics company. CardioDx creates clinically validated genomic tests to aid in assessing and tailoring care for people suffering from cardiovascular diseases such as coronary artery disease (CAD), cardiac arrhythmias, and heart failure.
  • Anthos Therapeutics is a clinical-stage biopharmaceutical company focused on developing and commercializing novel therapies for patients with high-risk cardiovascular disease.
  • Avinger creates precision medical device technology to combat Peripheral Artery Disease and assist patients in keeping their legs.
  • Milestone Pharmaceuticals is a pharmaceutical company that develops small-molecule therapeutics for the treatment of cardiovascular diseases.
  • MyoKardia is a precision medicine company that is discovering, developing, and commercializing targeted therapies for the treatment of serious and underserved rare cardiovascular diseases. Our initial focus is on treating heritable cardiomyopathies, a rare, genetically-driven form of heart failure.
  • On the basis of their proprietary AFFITOME technology, AFFiRiS develops first-in-class antigen-specific immunotherapies for the prevention and treatment of chronic illnesses. We believe that active immunization can play a significant role in preventing and treating chronic civilization illnesses such as atherosclerosis, diabetes, and neurodegenerative diseases.
  • Flow MedTech is a Health Wildcatters portfolio company that is developing an innovative therapy to reduce the risk of stroke in atrial fibrillation patients by preventing clot formation in the left atrial appendage. The company's goal is to design, develop, and commercialize novel catheter-based devices to reduce the risk of stroke.

Market Competition

The market for atherosclerosis is moderately competitive, with several key players. Some companies that are currently dominating the market are as follows GlaxoSmithKline Plc., Merck & Co., Inc., F. Hoffmann-La Roche Ltd., Isis, Pharmaceuticals, Inc., Anthera Pharmaceuticals, Novartis AG, Sanofi, Johnson and Johnson, Bayer AG, The Medicine Company and Cardium Therapeutics are some prominent players.

Recent Developments in the Atherosclerosis Market Are

  • In August 2022, AstraZeneca and Merck, known as MSD outside the United States and Canada, announced that the European Commission (EC) has approved LYNPARZA as monotherapy or in combination with endocrine therapy for the adjuvant treatment of adult patients with germline BRCA1/2 mutations (gBRCAm) and HER2-negative high-risk early breast cancer who have previously received neoadjuvant or adjuvant chemotherapy.
  • In July 2022, GSK plc announced that its wholly owned subsidiary, GSK Finance (No.3) plc, is expected to repurchase all its outstanding Exchangeable Senior Notes due 2023 for cash.
  • In June 2022, Novartis announced new data from the Phase 3 ASCLEPIOS I/II trials and the ALITHIOS open-label extension demonstrating that continuous Kesimpta® (ofatumumab) treatment significantly increased the odds of achieving no evidence of disease activity (NEDA-3) versus switching from teriflunomide. These findings were presented at the European Academy of Neurology (EAN) Annual Meeting, which is going to be held virtually on June 25-28, 2022, in Vienna, Austria.

Report Scope

Report Attribute Details
Market Value in 2023 USD 45,165.6 million
Market Value in 2033 USD 59,514.3 million
Growth Rate CAGR of 2.8% from 2023 to 2033
Base Year for Estimation 2022
Historical Data 2018 to 2022
Forecast Period 2023 to 2033
Quantitative Units Revenue in USD million and CAGR from 2023 to 2033
Report Coverage Revenue Forecast, Volume Forecast, Company Ranking, Competitive Landscape, Growth Factors, Trends, and Pricing Analysis
Segments Covered Therapy, Surgery, Distribution Channel, Region
Regions Covered North America; Latin America; Europe; Asia Pacific; The Middle East and Africa
Key Countries Profiled The United States, Canada, Brazil, Mexico, Germany, The United Kingdom, France, Spain, Italy, China, Japan, South Korea, GCC, South Africa, Israel
Key Companies Profiled GlaxoSmithKline plc.; Merck & Co., Inc.; F. Hoffmann-La Roche Ltd.; Isis Pharmaceuticals, Inc.; Anthera Pharmaceuticals; Novartis AG; Sanofi; Johnson and Johnson; Bayer AG; The Medicine Company; Cardium Therapeutics
Customization Available Upon Request

Key Segments Profiled in the Atherosclerosis Industry Survey

By Therapy:

  • Atherosclerosis Medications
  • Cholesterol-lowering Medications
  • Antiplatelet drugs and Anticoagulants
  • Atherosclerosis Beta Blockers
  • Diuretics or Water Pills
  • Angiotensin Converting Enzyme (Ace) Inhibitors
  • Other Atherosclerosis Treatment Therapies

By Surgery:

  • Bypass Surgery (Coronary Artery Bypass Grafting (CABG))
  • Angioplasty
  • Atherectomy

By Distribution Channel:

  • Hospitals
  • Pharmacies
  • Drug Stores
  • Retail Pharmacies
  • Clinics

By Region:

  • North America
  • Latin America
  • Europe
  • Asia Pacific
  • The Middle East and Africa

Frequently Asked Questions

What is Driving Demand in Asia Pacific?

An increasing geriatric population drives the Asia Pacific market.

What Drives Sales of Atherosclerosis?

The increasing prevalence of obesity and high cholesterol drives sales.

What was the Market Share of the United States in 2022?

The United States expanded at a CAGR of 32.4% in 2022.

How North America is Likley to Offer Lucrative Growth Opportunities?

The high prevalence of cardiovascular diseases and atherosclerosis in North America offers growth opportunities.

What is India’s Market Outlook?

India expanded at a CAGR of 4.4% in 2022.

Table of Content
  • 1. Executive Summary
  • 2. Market Overview
  • 3. Market Background
  • 4. Global Analysis 2018 to 2022 and Forecast, 2023 to 2033
  • 5. Global Analysis 2018 to 2022 and Forecast 2023 to 2033, By Therapy
    • 5.1. Atherosclerosis Medications
    • 5.2. Cholesterol-lowering Medications
    • 5.3. Antiplatelet Drugs and Anticoagulants
    • 5.4. Atherosclerosis Beta Blockers
    • 5.5. Diuretics or Water Pills
    • 5.6. Angiotensin Converting Enzyme (ACE) Inhibitors
    • 5.7. Others
  • 6. Global Analysis 2018 to 2022 and Forecast 2023 to 2033, By Surgery
    • 6.1. Bypass Surgery (Coronary Artery Bypass Grafting (CABG))
    • 6.2. Angioplasty
    • 6.3. Atherectomy
  • 7. Global Analysis 2018 to 2022 and Forecast 2023 to 2033, By Distribution Channel
    • 7.1. Hospitals
    • 7.2. Pharmacies
    • 7.3. Drug Stores
    • 7.4. Retail Pharmacies
    • 7.5. Clinics
  • 8. Global Analysis 2018 to 2022 and Forecast 2023 to 2033, By Region
    • 8.1. North America
    • 8.2. Latin America
    • 8.3. Western Europe
    • 8.4. Eastern Europe
    • 8.5. South Asia and Pacific
    • 8.6. East Asia
    • 8.7. Middle East and Africa
  • 9. North America Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
  • 10. Latin America Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
  • 11. Western Europe Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
  • 12. Eastern Europe Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
  • 13. South Asia and Pacific Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
  • 14. East Asia Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
  • 15. Middle East and Africa Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
  • 16. Key Countries Analysis
  • 17. Market Structure Analysis
  • 18. Competition Analysis
    • 18.1. GlaxoSmithKline plc.
    • 18.2. Merck & Co., Inc.
    • 18.3. F. Hoffmann-La Roche Ltd.
    • 18.4. Isis Pharmaceuticals, Inc.
    • 18.5. Anthera Pharmaceuticals
    • 18.6. Novartis AG
    • 18.7. Sanofi
    • 18.8. Johnson and Johnson
    • 18.9. Bayer AG
    • 18.10. The Medicine Company
    • 18.11. Cardium Therapeutics
  • 19. Assumptions & Acronyms Used
  • 20. Research Methodology

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