Complement system consists of more than 30 proteins and it operates as defense against infection. Composition of the 30 proteins in blood or serum is known as complement cascade which operates as the first protection mechanism against any antigen which enters in the body. In some patients the complement cascade can be weaker due to absence of few proteins or comparatively low concentration, hampering the body’s defense mechanism. The immune response to foreign particle entered into the body is often delayed in the person whose complement cascade is weaker. Various studies has shown that the complement deficiency is absence of functioning of one of the complement system proteins and these conditions are often goes as undiagnosed. Studies evaluated that only 10% of overall complement deficiencies are identified/ diagnosed. This represents large revenue generation potential in the global complement-targeted therapeutics market.
Complement-targeted Therapeutics Market: Drivers and Restraints
Complement-targeted therapeutics represent vast potential for the mechanism by which the body responds to the infection. Complement system also eliminates particulate substances, (like damaged or dying cells, microbes or immune complexes), furthermore it also helps in modulating adaptive immune responses. Complement-targeted therapeutics helps in normal mechanism of the immune system.
There are large number of clinical trials are going on to evaluate the use of complement-targeted therapeutics in managing the body’s first response as well as normal immune system functioning. With increasing prevalence of immune system diseases and vast clinical research in complement-targeted therapeutics, it is expected to offer significant revenue generation opportunity for the complement-targeted therapeutics market. With increasing prevalence of the geriatric population whose body is comparatively more susceptible to the infection due to weak immune system further expected to drive the growth of complement-targeted therapeutics market. Increasing prevalence of chronic diseases further expected to drive the growth of the complement-targeted therapeutics market. Whereas, large proportion of population living with complement deficiency goes undiagnosed, which may hamper the complement-targeted therapeutics market growth.
Complement-targeted Therapeutics Market: Overview
The global complement-targeted therapeutics market is expected to witness steady growth over the forecast period owing to increasing number of clinical trials and expected subsequent launches. The complement-targeted therapeutics market by indication is expected to be dominated by atypical haemolytic uraemic syndrome due to comparatively higher prevalence of the disease. By distribution channel, global complement-targeted therapeutics market is expected to be dominated by retail pharmacies due to higher patient footfall. Extensive clinical research activities going on the complement-targeted therapeutics market are expected to generate significant revenue generation opportunities in the near future. Increasing clinical studies around usefulness of the complement-targeted therapeutics around treating diseases such as 3-glomerulopathy, antibody-mediated acute rejection of kidney transplants, severe antiphospholipid syndrome, etc. further expected to offer significant revenue generation opportunity in global severe antiphospholipid syndrome market.
Complement-targeted Therapeutics Market: Regional Outlook
The global complement-targeted therapeutics market is expected to be dominated by North America due to higher product availability. Europe is expected to be the second most lucrative region in the global complement-targeted therapeutics market owing to higher disease prevalence. Latin America complement-targeted therapeutics market is expected to witness steady growth over the forecast period owing to increasing product availability in the region. Asia-Pacific complement-targeted therapeutics market is expected to witness exponential growth over the forecast period owing to increasing product adoption for the treatment. Middle East & Africa is expected to be the least lucrative region in the global complement-targeted therapeutics market due to least product adoption.
Complement-targeted Therapeutics Market: Key Players
The key players operating in the global complement-targeted therapeutics market are: Creative Biolabs, Complement UK, Novartis AG, Alexion Pharmaceuticals, Inc. Merck & Co., Inc., Pfizer Inc., Allergan plc, AbbVie, and others.
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The report covers exhaust analysis on:
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Regional analysis includes:
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Complement-targeted Therapeutics Market: Segmentation
The global complement-targeted therapeutics market is segmented on the basis of indication, distribution channel and region
Based on indication, the global complement-targeted therapeutics market is segmented as:
- Paroxysmal Nocturnal Haemoglobinuria
- Atypical Haemolytic Uraemic Syndrome (Ahus)
Based on the distribution channel, the global complement-targeted therapeutics market is segmented as:
- Hospital Pharmacies
- Retail Pharmacies
- Online Pharmacies
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