Myelodysplastic Syndrome Treatment Market Outlook (2022 to 2032)

The global myelodysplastic syndrome treatment market is poised to register a 5.9% CAGR, capturing a revenue share of USD 2,990.8 million in 2022, to reach USD 5,614.1 million by 2032.

Report Attribute Details
Myelodysplastic Syndrome Treatment Market Value (2022) USD 2,990.8 Million
Myelodysplastic Syndrome Treatment Market Anticipated Forecast Value (2032) USD 5,614.1 Million
Myelodysplastic Syndrome Treatment Market Projected Growth Rate (2022 to 2032) 5.9%

The rising adoption of myelodysplastic syndrome treatment can be attributed to new drugs and drug combinations that may work better and have less severe side effects that are the subject of studies.

Currently, the myelodysplastic syndrome treatment market trends are shaped by some of the most effective medications for treating MDS, classified as hypomethylating agents, such as azacitidine (Vidaza) and decitabine (Dacogen).

In the USA, myelodysplastic syndromes (MDS) occur at a rate of 4.8 cases for every 100,000 people, positively impacting the myelodysplastic syndrome treatment adoption trends.

In addition to this, the adoption of myelodysplastic syndrome treatment is on the surge as the number of new cases diagnosed each year seems to be increasing as the average age of the population increases. (Source: American Cancer Society).

Furthermore, diagnosis techniques such as blood count, peripheral blood smear test, microscopic exams, cytochemistry, flow cytometry and immunotherapy, cytogenetics, FISH, and PCR help in the detection of MDS, leading to the demand for myelodysplastic syndrome treatment.

What are the Key Myelodysplastic Syndrome Treatment Market Dynamics?

The myelodysplastic syndrome treatment market size is expected to expand to a significant extent in the coming few years due to increasing mutation in treatments, which cause myelodysplastic syndrome.

Moreover, growing number of patient pool of age 50 and above, and rising government support for cancer treatment augurs well for the myelodysplastic syndrome treatment market future trends.

However, unawareness about such treatments is one of the major factors mitigating the demand for myelodysplastic syndrome treatment.

The complexity and clonal heterogeneity of MDS also pose a challenge to the myelodysplastic syndrome treatment growth as it is frequently unknown, which mutations are early initiating events and are later events that only affect a subclone.

Despite these concerns, researchers are currently testing a number of strategies to try to enhance existing MDS therapeutics, in turn, create numerous myelodysplastic syndrome treatment market opportunities.

One of such myelodysplastic syndrome treatment market trends is the combination therapies that have either additive or synergistic effects in vitro.

Higher response rates than those seen with either drug alone may be possible when azacitidine is combined with lenalidomide or vorinostat (a deacetylase inhibitor currently FDA approved for treating cutaneous T-cell lymphoma).

The myelodysplastic syndrome treatment market outlook is to be swayed by a cooperative group trial in the United States and Canada that are currently investigating whether these combinations will improve patient outcomes in comparison to azacitidine monotherapy.

How is the North America Myelodysplastic Syndrome Treatment Market Evolving?

Due to the rising healthcare costs, and rising end-user demand for myelodysplastic syndrome treatment, North America is anticipated to control a myelodysplastic syndrome treatment market share of 34.6% in 2022.

And as the growth is further fostered by the focus of major players and non-profit organisations present on launching new initiatives and public awareness campaigns to inform people about gout disease and support medical professionals.

A growing awareness of MDS among Americans is expected to cause the USA to expand the myelodysplastic syndrome treatment market size over the forecast period.

What is the Growth Outlook for the Europe Myelodysplastic Syndrome Treatment Market?

Europe is predicted to experience significant growth and hold a market share of 31.1% in 2022 due to an increase in governmental initiatives for disease diagnosis and treatment.

As an illustration, the European LeukemiaNet WP8 promoted a programme with the goal of creating and regularly updating evidence- and consensus-based guidelines to provide clinical practise recommendations for standardised diagnostic and prognostic procedures and for an appropriate choice of therapeutic interventions in adult patients with primary MDS.

A significant factor that is anticipated to propel the myelodysplastic syndrome treatment market share of Europe is the increasing efforts made by pharmaceutical companies to introduce highly effective therapies for MDS.

How is the Start-up Ecosystem in the Myelodysplastic Syndrome Treatment Market?

The oral medication tamibarotene from Syros Pharmaceuticals has been given orphan drug designation (ODD) by the USA Food and Drug Administration (FDA) to treat myelodysplastic syndrome (MDS).

A selective retinoic acid receptor alpha (RAR) agonist is tamibarotene.

In the Phase III SELECT-MDS-1 clinical trial, oral therapy is currently being evaluated in addition to azacitidine to treat RARA-positive patients with recently discovered higher-risk MDS (HR-MDS).

The effectiveness and safety of the combination therapy are being evaluated in this ongoing trial.

The pivotal trial's results are expected by the company in the fourth quarter of 2019 or the first quarter of 2024.

In 2024, Syros also intends to submit a potential new drug application.

How is the Competition Landscape in the Myelodysplastic Syndrome Treatment Market?

The myelodysplastic syndrome treatment market is consolidated with a presence of few strong players from around the globe.

Some of the players identified in global myelodysplastic syndrome treatment market include Celgene Corporation, Otsuka Holdings Co., Ltd., Sandoz, Inc., Dr. Reddy's Laboratories, Inc., Accord Healthcare Ltd., Mylan N.V., Pfizer, Inc. etc.

Emerging trends in myelodysplastic syndrome treatment market are brought about as a result of the major players' adoption of several growth strategies, including product launches, acquisitions, and collaborations.

Some of the recent developments in the myelodysplastic syndrome treatment market are as follows:

  • Pevonedistat, an investigational drug from Takeda Pharmaceutical Company, has received FDA Breakthrough Therapy Designation for the treatment of patients with higher-risk myelodysplastic syndromes.
  • Gilead Sciences, Inc. and Forty-Seven, Inc. have entered into a definitive agreement under which Gilead will acquire Forty-Seven for USD 95.50 per share in cash. Magrolimab, Forty Seven's investigational lead product candidate.

Magrolimab is a monoclonal antibody in clinical development for the treatment of several cancers, including myelodysplastic syndrome (MDS), acute myeloid leukaemia (AML), and diffuse large B-cell lymphoma (DLBCL).

Report Scope

Report Attribute Details

Growth Rate

CAGR of 5.9% from 2022 to 2032

Base Year for Estimation

2021

Historical Data

2014 to 2020

Forecast Period

2022 to 2032

Quantitative Units

Revenue in USD Million and CAGR from 2022 to 2032

Report Coverage

Revenue Forecast, Volume Forecast, Company Ranking, Competitive Landscape, Growth Factors, Trends and Pricing Analysis

Segments Covered

Type, Treatment, Patient Group, Region

Regions Covered

North America; Latin America; Western Europe; Eastern Europe; Asia Pacific excluding Japan; Japan; The Middle East and Africa

Key Countries Profiled

USA, Canada, Brazil, Argentina, Germany, UK, France, Spain, Italy, Nordics, BENELUX, Australia & New Zealand, China, India, ASEAN, GCC, South Africa

Key Companies Profiled

Celgene Corporation; Otsuka Holdings Co., Ltd.; Sandoz, Inc.; Dr. Reddy's Laboratories, Inc.; Accord Healthcare Ltd.; Mylan N.V.; Pfizer, Inc.

Customization

Available Upon Request

Key Segments Profiled in the Myelodysplastic Syndrome Treatment Market Survey

By Type:

  • Refractory cytopenia with unilineage dysplasia (RCUD)
  • Refractory anemia with ringed sideroblasts (RARS)
  • Refractory cytopenia with multilineage dysplasia (RCMD)
  • Refractory anemia with excess blasts-1 (RAEB-1)
  • Refractory anemia with excess blasts-2 (RAEB-2)
  • Myelodysplastic syndrome, unclassified (MDS-U)
  • Myelodysplastic syndrome associated with isolated del(5q)

By Treatment:

  • Chemotherapy
  • Immunotherapy
  • Stem cell transplantation / bone marrow transplantation
  • Growth Factors

By Patient Group:

  • Above 50 years
  • Below 50 years

By Region:

  • North America
  • Latin America
  • Western Europe
  • Eastern Europe
  • Asia Pacific excluding Japan
  • Japan
  • The Middle East and Africa

Table of Content

  • 1. Executive Summary
  • 2. Market Overview
  • 3. Market Background
  • 4. Global Market Analysis 2017 to 2021 and Forecast, 2022 to 2032
  • 5. Global Market Analysis 2017 to 2021 and Forecast 2022 to 2032, By Type
    • 5.1. Refractory cytopenia with unilineage dysplasia (RCUD)
    • 5.2. Refractory anemia with ringed sideroblasts (RARS)
    • 5.3. Refractory cytopenia with multilineage dysplasia (RCMD)
    • 5.4. Refractory anemia with excess blasts to 1 (RAEB to 1)
    • 5.5. Refractory anemia with excess blasts to 2 (RAEB to 2)
    • 5.6. Myelodysplastic syndrome, unclassified (MDS to U)
    • 5.7. Myelodysplastic syndrome associated with isolated del(5q)
  • 6. Global Market 2017 to 2021 and Forecast 2022 to 2032, By Treatment
    • 6.1. Chemotherapy
    • 6.2. Immunotherapy
    • 6.3. Stem cell transplantation / bone marrow transplantation
    • 6.4. Growth Factors
  • 7. Global Market 2017 to 2021 and Forecast 2022 to 2032, By Patient Group
    • 7.1. Above 50 years
    • 7.2. Below 50 years
  • 8. Global Market 2017 to 2021 and Forecast 2022 to 2032, By Region
    • 8.1. North America
    • 8.2. Latin America
    • 8.3. Europe
    • 8.4. Asia Pacific
    • 8.5. MEA
  • 9. North America Market 2017 to 2021 and Forecast 2022 to 2032, By Country
  • 10. Latin America Market 2017 to 2021 and Forecast 2022 to 2032, By Country
  • 11. Europe Market 2017 to 2021 and Forecast 2022 to 2032, By Country
  • 12. Asia Pacific Market 2017 to 2021 and Forecast 2022 to 2032, By Country
  • 13. MEA Market 2017 to 2021 and Forecast 2022 to 2032, By Country
  • 14. Key Countries Market
  • 15. Market Structure Analysis
  • 16. Competition Analysis
    • 16.1. Celgene Corporation
    • 16.2. Otsuka Holdings Co., Ltd
    • 16.3. Sandoz, Inc.
    • 16.4. Dr. Reddy's Laboratories, Inc.
    • 16.5. Accord Healthcare Ltd.
    • 16.6. Mylan N.V.
    • 16.7. Pfizer, Inc.
  • 17. Assumptions & Acronyms Used
  • 18. Research Methodology

List of Tables

Table 1: Global Market Value (US$ Mn) Forecast by Region, 2017-2032

Table 2: Global Market Value (US$ Mn) Forecast by Type, 2017-2032

Table 3: Global Market Value (US$ Mn) Forecast by Treatment, 2017-2032

Table 4: Global Market Value (US$ Mn) Forecast by Patient Group, 2017-2032

Table 5: North America Market Value (US$ Mn) Forecast by Country, 2017-2032

Table 6: North America Market Value (US$ Mn) Forecast by Type, 2017-2032

Table 7: North America Market Value (US$ Mn) Forecast by Treatment, 2017-2032

Table 8: North America Market Value (US$ Mn) Forecast by Patient Group, 2017-2032

Table 9: Latin America Market Value (US$ Mn) Forecast by Country, 2017-2032

Table 10: Latin America Market Value (US$ Mn) Forecast by Type, 2017-2032

Table 11: Latin America Market Value (US$ Mn) Forecast by Treatment, 2017-2032

Table 12: Latin America Market Value (US$ Mn) Forecast by Patient Group, 2017-2032

Table 13: Europe Market Value (US$ Mn) Forecast by Country, 2017-2032

Table 14: Europe Market Value (US$ Mn) Forecast by Type, 2017-2032

Table 15: Europe Market Value (US$ Mn) Forecast by Treatment, 2017-2032

Table 16: Europe Market Value (US$ Mn) Forecast by Patient Group, 2017-2032

Table 17: Asia Pacific Market Value (US$ Mn) Forecast by Country, 2017-2032

Table 18: Asia Pacific Market Value (US$ Mn) Forecast by Type, 2017-2032

Table 19: Asia Pacific Market Value (US$ Mn) Forecast by Treatment, 2017-2032

Table 20: Asia Pacific Market Value (US$ Mn) Forecast by Patient Group, 2017-2032

Table 21: MEA Market Value (US$ Mn) Forecast by Country, 2017-2032

Table 22: MEA Market Value (US$ Mn) Forecast by Type, 2017-2032

Table 23: MEA Market Value (US$ Mn) Forecast by Treatment, 2017-2032

Table 24: MEA Market Value (US$ Mn) Forecast by Patient Group, 2017-2032

List of Figures

Figure 1: Global Market Value (US$ Mn) by Type, 2022-2032

Figure 2: Global Market Value (US$ Mn) by Treatment, 2022-2032

Figure 3: Global Market Value (US$ Mn) by Patient Group, 2022-2032

Figure 4: Global Market Value (US$ Mn) by Region, 2022-2032

Figure 5: Global Market Value (US$ Mn) Analysis by Region, 2017-2032

Figure 6: Global Market Value Share (%) and BPS Analysis by Region, 2022-2032

Figure 7: Global Market Y-o-Y Growth (%) Projections by Region, 2022-2032

Figure 8: Global Market Value (US$ Mn) Analysis by Type, 2017-2032

Figure 9: Global Market Value Share (%) and BPS Analysis by Type, 2022-2032

Figure 10: Global Market Y-o-Y Growth (%) Projections by Type, 2022-2032

Figure 11: Global Market Value (US$ Mn) Analysis by Treatment, 2017-2032

Figure 12: Global Market Value Share (%) and BPS Analysis by Treatment, 2022-2032

Figure 13: Global Market Y-o-Y Growth (%) Projections by Treatment, 2022-2032

Figure 14: Global Market Value (US$ Mn) Analysis by Patient Group, 2017-2032

Figure 15: Global Market Value Share (%) and BPS Analysis by Patient Group, 2022-2032

Figure 16: Global Market Y-o-Y Growth (%) Projections by Patient Group, 2022-2032

Figure 17: Global Market Attractiveness by Type, 2022-2032

Figure 18: Global Market Attractiveness by Treatment, 2022-2032

Figure 19: Global Market Attractiveness by Patient Group, 2022-2032

Figure 20: Global Market Attractiveness by Region, 2022-2032

Figure 21: North America Market Value (US$ Mn) by Type, 2022-2032

Figure 22: North America Market Value (US$ Mn) by Treatment, 2022-2032

Figure 23: North America Market Value (US$ Mn) by Patient Group, 2022-2032

Figure 24: North America Market Value (US$ Mn) by Country, 2022-2032

Figure 25: North America Market Value (US$ Mn) Analysis by Country, 2017-2032

Figure 26: North America Market Value Share (%) and BPS Analysis by Country, 2022-2032

Figure 27: North America Market Y-o-Y Growth (%) Projections by Country, 2022-2032

Figure 28: North America Market Value (US$ Mn) Analysis by Type, 2017-2032

Figure 29: North America Market Value Share (%) and BPS Analysis by Type, 2022-2032

Figure 30: North America Market Y-o-Y Growth (%) Projections by Type, 2022-2032

Figure 31: North America Market Value (US$ Mn) Analysis by Treatment, 2017-2032

Figure 32: North America Market Value Share (%) and BPS Analysis by Treatment, 2022-2032

Figure 33: North America Market Y-o-Y Growth (%) Projections by Treatment, 2022-2032

Figure 34: North America Market Value (US$ Mn) Analysis by Patient Group, 2017-2032

Figure 35: North America Market Value Share (%) and BPS Analysis by Patient Group, 2022-2032

Figure 36: North America Market Y-o-Y Growth (%) Projections by Patient Group, 2022-2032

Figure 37: North America Market Attractiveness by Type, 2022-2032

Figure 38: North America Market Attractiveness by Treatment, 2022-2032

Figure 39: North America Market Attractiveness by Patient Group, 2022-2032

Figure 40: North America Market Attractiveness by Country, 2022-2032

Figure 41: Latin America Market Value (US$ Mn) by Type, 2022-2032

Figure 42: Latin America Market Value (US$ Mn) by Treatment, 2022-2032

Figure 43: Latin America Market Value (US$ Mn) by Patient Group, 2022-2032

Figure 44: Latin America Market Value (US$ Mn) by Country, 2022-2032

Figure 45: Latin America Market Value (US$ Mn) Analysis by Country, 2017-2032

Figure 46: Latin America Market Value Share (%) and BPS Analysis by Country, 2022-2032

Figure 47: Latin America Market Y-o-Y Growth (%) Projections by Country, 2022-2032

Figure 48: Latin America Market Value (US$ Mn) Analysis by Type, 2017-2032

Figure 49: Latin America Market Value Share (%) and BPS Analysis by Type, 2022-2032

Figure 50: Latin America Market Y-o-Y Growth (%) Projections by Type, 2022-2032

Figure 51: Latin America Market Value (US$ Mn) Analysis by Treatment, 2017-2032

Figure 52: Latin America Market Value Share (%) and BPS Analysis by Treatment, 2022-2032

Figure 53: Latin America Market Y-o-Y Growth (%) Projections by Treatment, 2022-2032

Figure 54: Latin America Market Value (US$ Mn) Analysis by Patient Group, 2017-2032

Figure 55: Latin America Market Value Share (%) and BPS Analysis by Patient Group, 2022-2032

Figure 56: Latin America Market Y-o-Y Growth (%) Projections by Patient Group, 2022-2032

Figure 57: Latin America Market Attractiveness by Type, 2022-2032

Figure 58: Latin America Market Attractiveness by Treatment, 2022-2032

Figure 59: Latin America Market Attractiveness by Patient Group, 2022-2032

Figure 60: Latin America Market Attractiveness by Country, 2022-2032

Figure 61: Europe Market Value (US$ Mn) by Type, 2022-2032

Figure 62: Europe Market Value (US$ Mn) by Treatment, 2022-2032

Figure 63: Europe Market Value (US$ Mn) by Patient Group, 2022-2032

Figure 64: Europe Market Value (US$ Mn) by Country, 2022-2032

Figure 65: Europe Market Value (US$ Mn) Analysis by Country, 2017-2032

Figure 66: Europe Market Value Share (%) and BPS Analysis by Country, 2022-2032

Figure 67: Europe Market Y-o-Y Growth (%) Projections by Country, 2022-2032

Figure 68: Europe Market Value (US$ Mn) Analysis by Type, 2017-2032

Figure 69: Europe Market Value Share (%) and BPS Analysis by Type, 2022-2032

Figure 70: Europe Market Y-o-Y Growth (%) Projections by Type, 2022-2032

Figure 71: Europe Market Value (US$ Mn) Analysis by Treatment, 2017-2032

Figure 72: Europe Market Value Share (%) and BPS Analysis by Treatment, 2022-2032

Figure 73: Europe Market Y-o-Y Growth (%) Projections by Treatment, 2022-2032

Figure 74: Europe Market Value (US$ Mn) Analysis by Patient Group, 2017-2032

Figure 75: Europe Market Value Share (%) and BPS Analysis by Patient Group, 2022-2032

Figure 76: Europe Market Y-o-Y Growth (%) Projections by Patient Group, 2022-2032

Figure 77: Europe Market Attractiveness by Type, 2022-2032

Figure 78: Europe Market Attractiveness by Treatment, 2022-2032

Figure 79: Europe Market Attractiveness by Patient Group, 2022-2032

Figure 80: Europe Market Attractiveness by Country, 2022-2032

Figure 81: Asia Pacific Market Value (US$ Mn) by Type, 2022-2032

Figure 82: Asia Pacific Market Value (US$ Mn) by Treatment, 2022-2032

Figure 83: Asia Pacific Market Value (US$ Mn) by Patient Group, 2022-2032

Figure 84: Asia Pacific Market Value (US$ Mn) by Country, 2022-2032

Figure 85: Asia Pacific Market Value (US$ Mn) Analysis by Country, 2017-2032

Figure 86: Asia Pacific Market Value Share (%) and BPS Analysis by Country, 2022-2032

Figure 87: Asia Pacific Market Y-o-Y Growth (%) Projections by Country, 2022-2032

Figure 88: Asia Pacific Market Value (US$ Mn) Analysis by Type, 2017-2032

Figure 89: Asia Pacific Market Value Share (%) and BPS Analysis by Type, 2022-2032

Figure 90: Asia Pacific Market Y-o-Y Growth (%) Projections by Type, 2022-2032

Figure 91: Asia Pacific Market Value (US$ Mn) Analysis by Treatment, 2017-2032

Figure 92: Asia Pacific Market Value Share (%) and BPS Analysis by Treatment, 2022-2032

Figure 93: Asia Pacific Market Y-o-Y Growth (%) Projections by Treatment, 2022-2032

Figure 94: Asia Pacific Market Value (US$ Mn) Analysis by Patient Group, 2017-2032

Figure 95: Asia Pacific Market Value Share (%) and BPS Analysis by Patient Group, 2022-2032

Figure 96: Asia Pacific Market Y-o-Y Growth (%) Projections by Patient Group, 2022-2032

Figure 97: Asia Pacific Market Attractiveness by Type, 2022-2032

Figure 98: Asia Pacific Market Attractiveness by Treatment, 2022-2032

Figure 99: Asia Pacific Market Attractiveness by Patient Group, 2022-2032

Figure 100: Asia Pacific Market Attractiveness by Country, 2022-2032

Figure 101: MEA Market Value (US$ Mn) by Type, 2022-2032

Figure 102: MEA Market Value (US$ Mn) by Treatment, 2022-2032

Figure 103: MEA Market Value (US$ Mn) by Patient Group, 2022-2032

Figure 104: MEA Market Value (US$ Mn) by Country, 2022-2032

Figure 105: MEA Market Value (US$ Mn) Analysis by Country, 2017-2032

Figure 106: MEA Market Value Share (%) and BPS Analysis by Country, 2022-2032

Figure 107: MEA Market Y-o-Y Growth (%) Projections by Country, 2022-2032

Figure 108: MEA Market Value (US$ Mn) Analysis by Type, 2017-2032

Figure 109: MEA Market Value Share (%) and BPS Analysis by Type, 2022-2032

Figure 110: MEA Market Y-o-Y Growth (%) Projections by Type, 2022-2032

Figure 111: MEA Market Value (US$ Mn) Analysis by Treatment, 2017-2032

Figure 112: MEA Market Value Share (%) and BPS Analysis by Treatment, 2022-2032

Figure 113: MEA Market Y-o-Y Growth (%) Projections by Treatment, 2022-2032

Figure 114: MEA Market Value (US$ Mn) Analysis by Patient Group, 2017-2032

Figure 115: MEA Market Value Share (%) and BPS Analysis by Patient Group, 2022-2032

Figure 116: MEA Market Y-o-Y Growth (%) Projections by Patient Group, 2022-2032

Figure 117: MEA Market Attractiveness by Type, 2022-2032

Figure 118: MEA Market Attractiveness by Treatment, 2022-2032

Figure 119: MEA Market Attractiveness by Patient Group, 2022-2032

Figure 120: MEA Market Attractiveness by Country, 2022-2032

Frequently Asked Questions

What is the Growth Outlook for the Myelodysplastic Syndrome Treatment Market?

The global myelodysplastic syndrome treatment market is set to advance at a CAGR of 5.9% from 2022 to 2032.

What is the Anticipated Myelodysplastic Syndrome Treatment Market Share of North America?

North America is likely to hold a myelodysplastic syndrome treatment market share of 34.6% in 2022.

What is the Future of Myelodysplastic Syndrome Treatment Market?

The myelodysplastic syndrome treatment market is likely to account for USD 5,614.1 million by 2032.

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