Myelodysplastic Syndrome Treatment Market Outlook (2022-2032)

[324 Pages Report] The global myelodysplastic syndrome treatment market is poised to register a 5.9% CAGR, capturing a revenue share of US$ 2,990.8 million in 2022, to reach US$ 5,614.1 million by 2032.

Report Attribute Details
Myelodysplastic Syndrome Treatment Market Value (2022) US$ 2,990.8 Million
Myelodysplastic Syndrome Treatment Market Anticipated Forecast Value (2032) US$ 5,614.1 Million
Myelodysplastic Syndrome Treatment Market Projected Growth Rate (2022-2032) 5.9%

The rising adoption of myelodysplastic syndrome treatment can be attributed to new drugs and drug combinations that may work better and have less severe side effects that are the subject of studies.

Currently, the myelodysplastic syndrome treatment market trends are shaped by some of the most effective medications for treating MDS, classified as hypomethylating agents, such as azacitidine (Vidaza) and decitabine (Dacogen).

In the U.S., myelodysplastic syndromes (MDS) occur at a rate of 4.8 cases for every 100,000 people, positively impacting the myelodysplastic syndrome treatment adoption trends.

In addition to this, the adoption of myelodysplastic syndrome treatment is on the surge as the number of new cases diagnosed each year seems to be increasing as the average age of the population increases. (Source: American Cancer Society).

Furthermore, diagnosis techniques such as blood count, peripheral blood smear test, microscopic exams, cytochemistry, flow cytometry and immunotherapy, cytogenetics, FISH, and PCR help in the detection of MDS, leading to the demand for myelodysplastic syndrome treatment.

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What are the Key Myelodysplastic Syndrome Treatment Market Dynamics?

The myelodysplastic syndrome treatment market size is expected to expand to a significant extent in the coming few years due to increasing mutation in treatments, which cause myelodysplastic syndrome.

Moreover, growing number of patient pool of age 50 and above, and rising government support for cancer treatment augurs well for the myelodysplastic syndrome treatment market future trends.

However, unawareness about such treatments is one of the major factors mitigating the demand for myelodysplastic syndrome treatment.

The complexity and clonal heterogeneity of MDS also pose a challenge to the myelodysplastic syndrome treatment growth as it is frequently unknown, which mutations are early initiating events and are later events that only affect a subclone.

Despite these concerns, researchers are currently testing a number of strategies to try to enhance existing MDS therapeutics, in turn, create numerous myelodysplastic syndrome treatment market opportunities.

One of such myelodysplastic syndrome treatment market trends is the combination therapies that have either additive or synergistic effects in vitro.

Higher response rates than those seen with either drug alone may be possible when azacitidine is combined with lenalidomide or vorinostat (a deacetylase inhibitor currently FDA approved for treating cutaneous T-cell lymphoma).

The myelodysplastic syndrome treatment market outlook is to be swayed by a cooperative group trial in the United States and Canada that are currently investigating whether these combinations will improve patient outcomes in comparison to azacitidine monotherapy.

How is the North America Myelodysplastic Syndrome Treatment Market Evolving?

Due to the rising healthcare costs, and rising end-user demand for myelodysplastic syndrome treatment, North America is anticipated to control a myelodysplastic syndrome treatment market share of 34.6% in 2022.

And as the growth is further fostered by the focus of major players and non-profit organisations present on launching new initiatives and public awareness campaigns to inform people about gout disease and support medical professionals.

A growing awareness of MDS among Americans is expected to cause the U.S. to expand the myelodysplastic syndrome treatment market size over the forecast period.

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What is the Growth Outlook for the Europe Myelodysplastic Syndrome Treatment Market?

Europe is predicted to experience significant growth and hold a market share of 31.1% in 2022 due to an increase in governmental initiatives for disease diagnosis and treatment.

As an illustration, the European LeukemiaNet WP8 promoted a programme with the goal of creating and regularly updating evidence- and consensus-based guidelines to provide clinical practise recommendations for standardised diagnostic and prognostic procedures and for an appropriate choice of therapeutic interventions in adult patients with primary MDS.

A significant factor that is anticipated to propel the myelodysplastic syndrome treatment market share of Europe is the increasing efforts made by pharmaceutical companies to introduce highly effective therapies for MDS.

How is the Start-up Ecosystem in the Myelodysplastic Syndrome Treatment Market?

The oral medication tamibarotene from Syros Pharmaceuticals has been given orphan drug designation (ODD) by the US Food and Drug Administration (FDA) to treat myelodysplastic syndrome (MDS).

A selective retinoic acid receptor alpha (RAR) agonist is tamibarotene.

In the Phase III SELECT-MDS-1 clinical trial, oral therapy is currently being evaluated in addition to azacitidine to treat RARA-positive patients with recently discovered higher-risk MDS (HR-MDS).

The effectiveness and safety of the combination therapy are being evaluated in this ongoing trial.

The pivotal trial's results are expected by the company in the fourth quarter of 2019 or the first quarter of 2024.

In 2024, Syros also intends to submit a potential new drug application.

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How is the Competition Landscape in the Myelodysplastic Syndrome Treatment Market?

The myelodysplastic syndrome treatment market is consolidated with a presence of few strong players from around the globe.

Some of the players identified in global myelodysplastic syndrome treatment market include Celgene Corporation, Otsuka Holdings Co., Ltd., Sandoz, Inc., Dr. Reddy's Laboratories, Inc., Accord Healthcare Ltd., Mylan N.V., Pfizer, Inc. etc.

Emerging trends in myelodysplastic syndrome treatment market are brought about as a result of the major players' adoption of several growth strategies, including product launches, acquisitions, and collaborations.

Some of the recent developments in the myelodysplastic syndrome treatment market are as follows:

  • Pevonedistat, an investigational drug from Takeda Pharmaceutical Company, has received FDA Breakthrough Therapy Designation for the treatment of patients with higher-risk myelodysplastic syndromes.
  • Gilead Sciences, Inc. and Forty-Seven, Inc. have entered into a definitive agreement under which Gilead will acquire Forty-Seven for $95.50 per share in cash. Magrolimab, Forty Seven's investigational lead product candidate.

Magrolimab is a monoclonal antibody in clinical development for the treatment of several cancers, including myelodysplastic syndrome (MDS), acute myeloid leukaemia (AML), and diffuse large B-cell lymphoma (DLBCL).

Report Scope

Report Attribute Details

Growth Rate

CAGR of 5.9% from 2022 to 2032

Base Year for Estimation

2021

Historical Data

2014-2020

Forecast Period

2022-2032

Quantitative Units

Revenue in USD Million and CAGR from 2022-2032

Report Coverage

Revenue Forecast, Volume Forecast, Company Ranking, Competitive Landscape, Growth Factors, Trends and Pricing Analysis

Segments Covered

  • Type
  • Treatment
  • Patient Group
  • Region

Regions Covered

  • North America
  • Latin America
  • Western Europe
  • Eastern Europe
  • Asia Pacific excluding Japan
  • Japan
  • The Middle East and Africa

Key Countries Profiled

  • USA
  • Canada
  • Brazil
  • Argentina
  • Germany
  • UK
  • France
  • Spain
  • Italy
  • Nordics
  • BENELUX
  • Australia & New Zealand
  • China
  • India
  • ASEAN
  • GCC
  • South Africa

Key Companies Profiled

  • Celgene Corporation
  • Otsuka Holdings Co., Ltd.
  • Sandoz, Inc.
  • Dr. Reddy's Laboratories, Inc.
  • Accord Healthcare Ltd.
  • Mylan N.V.
  • Pfizer, Inc.

Customization

Available Upon Request

Key Segments Profiled in the Myelodysplastic Syndrome Treatment Market Survey

By Type:

  • Refractory cytopenia with unilineage dysplasia (RCUD)
  • Refractory anemia with ringed sideroblasts (RARS)
  • Refractory cytopenia with multilineage dysplasia (RCMD)
  • Refractory anemia with excess blasts-1 (RAEB-1)
  • Refractory anemia with excess blasts-2 (RAEB-2)
  • Myelodysplastic syndrome, unclassified (MDS-U)
  • Myelodysplastic syndrome associated with isolated del(5q)

By Treatment:

  • Chemotherapy
  • Immunotherapy
  • Stem cell transplantation / bone marrow transplantation
  • Growth Factors

By Patient Group:

  • Above 50 years
  • Below 50 years

By Region:

  • North America
  • Latin America
  • Western Europe
  • Eastern Europe
  • Asia Pacific excluding Japan
  • Japan
  • The Middle East and Africa

Frequently Asked Questions

What is the Growth Outlook for the Myelodysplastic Syndrome Treatment Market?

The global myelodysplastic syndrome treatment market is set to advance at a CAGR of 5.9% from 2022 to 2032.

What is the Anticipated Myelodysplastic Syndrome Treatment Market Share of North America?

North America is likely to hold a myelodysplastic syndrome treatment market share of 34.6% in 2022.

What is the Future of Myelodysplastic Syndrome Treatment Market?

The myelodysplastic syndrome treatment market is likely to account for US$ 5,614.1 million by 2032.

Table of Content
1. Executive Summary

    1.1. Global Market Outlook

    1.2. Demand-side Trends

    1.3. Supply-side Trends

    1.4. Technology Roadmap Analysis

    1.5. Analysis and Recommendations

2. Market Overview

    2.1. Market Coverage / Taxonomy

    2.2. Market Definition / Scope / Limitations

3. Market Background

    3.1. Market Dynamics

        3.1.1. Drivers

        3.1.2. Restraints

        3.1.3. Opportunity

        3.1.4. Trends

    3.2. Scenario Forecast

        3.2.1. Demand in Optimistic Scenario

        3.2.2. Demand in Likely Scenario

        3.2.3. Demand in Conservative Scenario

    3.3. Opportunity Map Analysis

    3.4. Investment Feasibility Matrix

    3.5. PESTLE and Porter’s Analysis

    3.6. Regulatory Landscape

        3.6.1. By Key Regions

        3.6.2. By Key Countries

    3.7. Regional Parent Market Outlook

4. Global Market Analysis 2017-2021 and Forecast, 2022-2032

    4.1. Historical Market Size Value (US$ Mn) Analysis, 2017-2021

    4.2. Current and Future Market Size Value (US$ Mn) Projections, 2022-2032

        4.2.1. Y-o-Y Growth Trend Analysis

        4.2.2. Absolute $ Opportunity Analysis

5. Global Market Analysis 2017-2021 and Forecast 2022-2032, By Type

    5.1. Introduction / Key Findings

    5.2. Historical Market Size Value (US$ Mn) Analysis By Type, 2017-2021

    5.3. Current and Future Market Size Value (US$ Mn) Analysis and Forecast By Type, 2022-2032

        5.3.1. Refractory cytopenia with unilineage dysplasia (RCUD)

        5.3.2. Refractory anemia with ringed sideroblasts (RARS)

        5.3.3. Refractory cytopenia with multilineage dysplasia (RCMD)

        5.3.4. Refractory anemia with excess blasts-1 (RAEB-1)

        5.3.5. Refractory anemia with excess blasts-2 (RAEB-2)

        5.3.6. Myelodysplastic syndrome, unclassified (MDS-U)

        5.3.7. Myelodysplastic syndrome associated with isolated del(5q)

    5.4. Y-o-Y Growth Trend Analysis By Type, 2017-2021

    5.5. Absolute $ Opportunity Analysis By Type, 2022-2032

6. Global Market 2017-2021 and Forecast 2022-2032, By Treatment

    6.1. Introduction / Key Findings

    6.2. Historical Market Size Value (US$ Mn) Analysis By Treatment, 2017-2021

    6.3. Current and Future Market Size Value (US$ Mn) Analysis and Forecast By Treatment, 2022-2032

        6.3.1. Chemotherapy

        6.3.2. Immunotherapy

        6.3.3. Stem cell transplantation / bone marrow transplantation

        6.3.4. Growth Factors

    6.4. Y-o-Y Growth Trend Analysis By Treatment, 2017-2021

    6.5. Absolute $ Opportunity Analysis By Treatment, 2022-2032

7. Global Market 2017-2021 and Forecast 2022-2032, By Patient Group

    7.1. Introduction / Key Findings

    7.2. Historical Market Size Value (US$ Mn) Analysis By Patient Group, 2017-2021

    7.3. Current and Future Market Size Value (US$ Mn) Analysis and Forecast By Patient Group, 2022-2032

        7.3.1. Above 50 years

        7.3.2. Below 50 years

    7.4. Y-o-Y Growth Trend Analysis By Patient Group, 2017-2021

    7.5. Absolute $ Opportunity Analysis By Patient Group, 2022-2032

8. Global Market 2017-2021 and Forecast 2022-2032, By Region

    8.1. Introduction

    8.2. Historical Market Size Value (US$ Mn) Analysis By Region, 2017-2021

    8.3. Current Market Size Value (US$ Mn) Analysis and Forecast By Region, 2022-2032

        8.3.1. North America

        8.3.2. Latin America

        8.3.3. Europe

        8.3.4. Asia Pacific

        8.3.5. MEA

    8.4. Market Attractiveness Analysis By Region

9. North America Market 2017-2021 and Forecast 2022-2032, By Country

    9.1. Historical Market Size Value (US$ Mn) Trend Analysis By Market Taxonomy, 2017-2021

    9.2. Market Size Value (US$ Mn) Forecast By Market Taxonomy, 2022-2032

        9.2.1. By Country

            9.2.1.1. U.S.

            9.2.1.2. Canada

        9.2.2. By Type

        9.2.3. By Treatment

        9.2.4. By Patient Group

    9.3. Market Attractiveness Analysis

        9.3.1. By Country

        9.3.2. By Type

        9.3.3. By Treatment

        9.3.4. By Patient Group

    9.4. Key Takeaways

10. Latin America Market 2017-2021 and Forecast 2022-2032, By Country

    10.1. Historical Market Size Value (US$ Mn) Trend Analysis By Market Taxonomy, 2017-2021

    10.2. Market Size Value (US$ Mn) Forecast By Market Taxonomy, 2022-2032

        10.2.1. By Country

            10.2.1.1. Brazil

            10.2.1.2. Mexico

            10.2.1.3. Rest of Latin America

        10.2.2. By Type

        10.2.3. By Treatment

        10.2.4. By Patient Group

    10.3. Market Attractiveness Analysis

        10.3.1. By Country

        10.3.2. By Type

        10.3.3. By Treatment

        10.3.4. By Patient Group

    10.4. Key Takeaways

11. Europe Market 2017-2021 and Forecast 2022-2032, By Country

    11.1. Historical Market Size Value (US$ Mn) Trend Analysis By Market Taxonomy, 2017-2021

    11.2. Market Size Value (US$ Mn) Forecast By Market Taxonomy, 2022-2032

        11.2.1. By Country

            11.2.1.1. Germany

            11.2.1.2. U.K.

            11.2.1.3. France

            11.2.1.4. Spain

            11.2.1.5. Italy

            11.2.1.6. Rest of Europe

        11.2.2. By Type

        11.2.3. By Treatment

        11.2.4. By Patient Group

    11.3. Market Attractiveness Analysis

        11.3.1. By Country

        11.3.2. By Type

        11.3.3. By Treatment

        11.3.4. By Patient Group

    11.4. Key Takeaways

12. Asia Pacific Market 2017-2021 and Forecast 2022-2032, By Country

    12.1. Historical Market Size Value (US$ Mn) Trend Analysis By Market Taxonomy, 2017-2021

    12.2. Market Size Value (US$ Mn) Forecast By Market Taxonomy, 2022-2032

        12.2.1. By Country

            12.2.1.1. China

            12.2.1.2. Japan

            12.2.1.3. South Korea

            12.2.1.4. Malaysia

            12.2.1.5. Singapore

            12.2.1.6. Australia

            12.2.1.7. Rest of Asia Pacific

        12.2.2. By Type

        12.2.3. By Treatment

        12.2.4. By Patient Group

    12.3. Market Attractiveness Analysis

        12.3.1. By Country

        12.3.2. By Type

        12.3.3. By Treatment

        12.3.4. By Patient Group

    12.4. Key Takeaways

13. MEA Market 2017-2021 and Forecast 2022-2032, By Country

    13.1. Historical Market Size Value (US$ Mn) Trend Analysis By Market Taxonomy, 2017-2021

    13.2. Market Size Value (US$ Mn) Forecast By Market Taxonomy, 2022-2032

        13.2.1. By Country

            13.2.1.1. GCC Countries

            13.2.1.2. South Africa

            13.2.1.3. Israel

            13.2.1.4. Rest of MEA

        13.2.2. By Type

        13.2.3. By Treatment

        13.2.4. By Patient Group

    13.3. Market Attractiveness Analysis

        13.3.1. By Country

        13.3.2. By Type

        13.3.3. By Treatment

        13.3.4. By Patient Group

    13.4. Key Takeaways

14. Key Countries Market

    14.1. U.K.

        14.1.1. Pricing Analysis

        14.1.2. Market Share Analysis, 2021

            14.1.2.1. By Type

            14.1.2.2. By Treatment

            14.1.2.3. By Patient Group

    14.2. Canada

        14.2.1. Pricing Analysis

        14.2.2. Market Share Analysis, 2021

            14.2.2.1. By Type

            14.2.2.2. By Treatment

            14.2.2.3. By Patient Group

    14.3. Brazil

        14.3.1. Pricing Analysis

        14.3.2. Market Share Analysis, 2021

            14.3.2.1. By Type

            14.3.2.2. By Treatment

            14.3.2.3. By Patient Group

    14.4. Mexico

        14.4.1. Pricing Analysis

        14.4.2. Market Share Analysis, 2021

            14.4.2.1. By Type

            14.4.2.2. By Treatment

            14.4.2.3. By Patient Group

    14.5. Rest of Latin America

        14.5.1. Pricing Analysis

        14.5.2. Market Share Analysis, 2021

            14.5.2.1. By Type

            14.5.2.2. By Treatment

            14.5.2.3. By Patient Group

    14.6. Germany

        14.6.1. Pricing Analysis

        14.6.2. Market Share Analysis, 2021

            14.6.2.1. By Type

            14.6.2.2. By Treatment

            14.6.2.3. By Patient Group

    14.7. U.K.

        14.7.1. Pricing Analysis

        14.7.2. Market Share Analysis, 2021

            14.7.2.1. By Type

            14.7.2.2. By Treatment

            14.7.2.3. By Patient Group

    14.8. France

        14.8.1. Pricing Analysis

        14.8.2. Market Share Analysis, 2021

            14.8.2.1. By Type

            14.8.2.2. By Treatment

            14.8.2.3. By Patient Group

    14.9. Spain

        14.9.1. Pricing Analysis

        14.9.2. Market Share Analysis, 2021

            14.9.2.1. By Type

            14.9.2.2. By Treatment

            14.9.2.3. By Patient Group

    14.10. Italy

        14.10.1. Pricing Analysis

        14.10.2. Market Share Analysis, 2021

            14.10.2.1. By Type

            14.10.2.2. By Treatment

            14.10.2.3. By Patient Group

    14.11. Rest of Europe

        14.11.1. Pricing Analysis

        14.11.2. Market Share Analysis, 2021

            14.11.2.1. By Type

            14.11.2.2. By Treatment

            14.11.2.3. By Patient Group

    14.12. China

        14.12.1. Pricing Analysis

        14.12.2. Market Share Analysis, 2021

            14.12.2.1. By Type

            14.12.2.2. By Treatment

            14.12.2.3. By Patient Group

    14.13. Japan

        14.13.1. Pricing Analysis

        14.13.2. Market Share Analysis, 2021

            14.13.2.1. By Type

            14.13.2.2. By Treatment

            14.13.2.3. By Patient Group

    14.14. South Korea

        14.14.1. Pricing Analysis

        14.14.2. Market Share Analysis, 2021

            14.14.2.1. By Type

            14.14.2.2. By Treatment

            14.14.2.3. By Patient Group

    14.15. Malaysia

        14.15.1. Pricing Analysis

        14.15.2. Market Share Analysis, 2021

            14.15.2.1. By Type

            14.15.2.2. By Treatment

            14.15.2.3. By Patient Group

    14.16. Singapore

        14.16.1. Pricing Analysis

        14.16.2. Market Share Analysis, 2021

            14.16.2.1. By Type

            14.16.2.2. By Treatment

            14.16.2.3. By Patient Group

    14.17. Australia

        14.17.1. Pricing Analysis

        14.17.2. Market Share Analysis, 2021

            14.17.2.1. By Type

            14.17.2.2. By Treatment

            14.17.2.3. By Patient Group

    14.18. Rest of Asia Pacific

        14.18.1. Pricing Analysis

        14.18.2. Market Share Analysis, 2021

            14.18.2.1. By Type

            14.18.2.2. By Treatment

            14.18.2.3. By Patient Group

    14.19. GCC Countries

        14.19.1. Pricing Analysis

        14.19.2. Market Share Analysis, 2021

            14.19.2.1. By Type

            14.19.2.2. By Treatment

            14.19.2.3. By Patient Group

    14.20. South Africa

        14.20.1. Pricing Analysis

        14.20.2. Market Share Analysis, 2021

            14.20.2.1. By Type

            14.20.2.2. By Treatment

            14.20.2.3. By Patient Group

    14.21. Israel

        14.21.1. Pricing Analysis

        14.21.2. Market Share Analysis, 2021

            14.21.2.1. By Type

            14.21.2.2. By Treatment

            14.21.2.3. By Patient Group

    14.22. Rest of MEA

        14.22.1. Pricing Analysis

        14.22.2. Market Share Analysis, 2021

            14.22.2.1. By Type

            14.22.2.2. By Treatment

            14.22.2.3. By Patient Group

15. Market Structure Analysis

    15.1. Competition Dashboard

    15.2. Competition Benchmarking

    15.3. Market Share Analysis of Top Players

        15.3.1. By Regional

        15.3.2. By Type

        15.3.3. By Treatment

        15.3.4. By Patient Group

16. Competition Analysis

    16.1. Competition Deep Dive

        16.1.1. Celgene Corporation

            16.1.1.1. Overview

            16.1.1.2. Product Portfolio

            16.1.1.3. Profitability by Market Segments

            16.1.1.4. Sales Footprint

            16.1.1.5. Strategy Overview

                16.1.1.5.1. Marketing Strategy

        16.1.2. Otsuka Holdings Co., Ltd

            16.1.2.1. Overview

            16.1.2.2. Product Portfolio

            16.1.2.3. Profitability by Market Segments

            16.1.2.4. Sales Footprint

            16.1.2.5. Strategy Overview

                16.1.2.5.1. Marketing Strategy

        16.1.3. Sandoz, Inc.

            16.1.3.1. Overview

            16.1.3.2. Product Portfolio

            16.1.3.3. Profitability by Market Segments

            16.1.3.4. Sales Footprint

            16.1.3.5. Strategy Overview

                16.1.3.5.1. Marketing Strategy

        16.1.4. Dr. Reddy's Laboratories, Inc.

            16.1.4.1. Overview

            16.1.4.2. Product Portfolio

            16.1.4.3. Profitability by Market Segments

            16.1.4.4. Sales Footprint

            16.1.4.5. Strategy Overview

                16.1.4.5.1. Marketing Strategy

        16.1.5. Accord Healthcare Ltd.

            16.1.5.1. Overview

            16.1.5.2. Product Portfolio

            16.1.5.3. Profitability by Market Segments

            16.1.5.4. Sales Footprint

            16.1.5.5. Strategy Overview

                16.1.5.5.1. Marketing Strategy

        16.1.6. Mylan N.V.,

            16.1.6.1. Overview

            16.1.6.2. Product Portfolio

            16.1.6.3. Profitability by Market Segments

            16.1.6.4. Sales Footprint

            16.1.6.5. Strategy Overview

                16.1.6.5.1. Marketing Strategy

        16.1.7. Pfizer, Inc.

            16.1.7.1. Overview

            16.1.7.2. Product Portfolio

            16.1.7.3. Profitability by Market Segments

            16.1.7.4. Sales Footprint

            16.1.7.5. Strategy Overview

                16.1.7.5.1. Marketing Strategy

17. Assumptions & Acronyms Used

18. Research Methodology
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