The market for Threonine Acids is anticipated to witness a substantial growth, with the sales projected to be nearly about USD 1,405.0 million towards the end of 2025 and continue to increase further with a compound annual growth rate of 4.9% in value to be more than USD 2,268.9 million by 2035.
The global market of threonine acids is flourishing at a rapid rate, supported by its requirement in animal nutrition, drug application, and nutritional functional foods. Increasing interest in protein efficiency of animal feed has rendered L-Threonine a vital supplement for the poultry and swine industries, as it enhances growth, immune status, and intestinal integrity.
Major producers such as Evonik Industries and Ajinomoto Co., Inc. are taking advantage of this demand through increasing their capacity for threonine production to meet the uniform and economical needs of feed mills across the globe.
The functional food and nutraceutical industry is also observing an increase in demand parallelly, as the role of L-Threonine in muscle restoration, metabolism, and intestinal well-being coincides with the fast-growing trend for high-protein foods and sport nutrition products. Companies like Kyowa Hakko Bio Co., Ltd. are making investments in fermentation-based manufacturing to meet high-purity threonine for dietary supplements.
Growing attention towards plant protein sources is further driving this change, with manufacturers developing new variants of pea and soy-based protein blends supplemented with threonine. Pharmaceutical industry is employing L-Threonine for the development of drugs against neurological diseases, metabolic health, and the immune system.
Pharmaceutical companies such as SIGMA TAU Pharmaceuticals and Mitsubishi Tanabe Pharma Corporation are including threonine in new generation drug formulations, highlighting its increased role in therapeutic and clinical nutrition applications.
| Attributes | Description |
|---|---|
| Estimated Size (2025E) | USD 1,405.0 million |
| Projected Value (2035F) | USD 2,268.9 million |
| Value-based CAGR (2025 to 2035) | 4.9% |
Furthermore, the market is benefiting from biotechnological advancements in fermentation-based amino acid production. Companies like Tianjin Tianyao Pharmaceuticals Co., Ltd. and Shanghai Kyowa Amino Acid Co., Ltd. are optimizing cost-effective biosynthesis processes that enhance yield efficiency and lower production costs.
With a global momentum towards effective and sustainable protein consumption, the market will keep on growing, leading threonine acids to be an essential part of contemporary medicine and nutrition.
The below table presents a comparative assessment of the variation in CAGR over six months for the base year (2024) and current year (2025) for the global Threonine Acids market. This analysis reveals crucial shifts in performance and indicates revenue realization patterns, thus providing stakeholders with a better vision of the growth trajectory over the year. The first half of the year, or H1, spans from January to June. The second half, H2, includes the months from July to December.
| Particular | Value CAGR |
|---|---|
| H1 | 3.9% (2024 to 2034) |
| H2 | 4.2% (2024 to 2034) |
| H1 | 4.5% (2025 to 2035) |
| H2 | 4.9% (2025 to 2035) |
In the first half (H1) of the decade from 2025 to 2035, the business is predicted to surge at a CAGR of 3.9%, followed by a slightly higher growth rate of 4.2% in the second half (H2) of the same decade. Moving into the subsequent period, from H1 2025 to H2 2035, the CAGR is projected to increase slightly to 4.5% in the first half and remain relatively moderate at 4.9% in the second half. In the first half (H1) the sector witnessed a decrease of 30 BPS while in the second half (H2), the business witnessed an increase of 10 BPS.
Fermentation-Based Production of Threonine Takes Centre Stage
The transition towards the production of threonine on a fermentation-based scale is changing the amino acid market by making it more environment-friendly, eliminating dependence on man-made chemical processing, and pushing purity levels upwards.
Ajinomoto Co., Inc. and Kyowa Hakko Bio Co., Ltd. are leading the charge towards this change, leveraging Corynebacterium glutamicum-based fermentation to create top-quality L-Threonine. Such production is not only cost-efficient and on a mass scale but also meets the industry's drive towards environmentally friendly biomanufacturing.
Unprocessed and natural amino acids are fuelling investment in biotechnology as producers focus on enhanced microbial strain optimization for better yields. Additionally, Shanghai Kyowa Amino Acid Co., Ltd. has expanded its fermentation-based production facilities, bolstered the global supply chain while restricted dependence on traditional extraction methods.
As regulatory agencies promote clean-label ingredients, the trend is likely to shape the future of threonine production. As regulatory agencies push towards clean-label ingredients, the trend is likely to shape the future of threonine production.
Plant-Based Threonine Sources Growth
The growing consumer trend towards plant-based nutrition is forcing manufacturers to find non-animal-based sources of threonine. Summit Ingredients and Yangzhou Gami Biochem Co., Ltd. are leading the use of soy and pea protein sources to isolate and enrich threonine in vegan dietary supplements and plant-based meat substitutes.
As the market for vegan proteins is expected to expand exponentially, firms are placing bets on plant-based amino acids through fermentation technology that replicates the nutritional quality of animal-based threonine. This shift is in accordance with the trend towards ethical, sustainable, and allergen-free protein sources from consumers.
Also, improvements in precision fermentation enable manufacturers to reach high purity rates, and therefore, plant-based threonine is becoming an attractive choice for sports nutrition and pharmaceutical applications. As large food-tech players add plant-based amino acids to their products, this trend is poised to shake up the functional food market.
Drug-Quality Threonine for Metabolic Diseases
Pharmaceutical companies are increasingly coming to appreciate the therapeutic value of L-Threonine, particularly in the control of metabolic and neurological diseases. Mitsubishi Tanabe Pharma Corporation and SIGMA TAU Pharmaceuticals have developed threonine-enriched preparations facilitating liver detoxication, muscle regeneration, and balance in neurotransmitters.
Amino acid-based medical nutrition is gaining popularity, especially in the clinical environment where protein supplement formulations to specific requirements are called for by the patient. L-Threonine's role as a collagen synthesis and immune system activator puts it in the premier position among wound-healing product formulations and healing diets.
Additionally, as liver conditions and neurological conditions continue to grow, Tianjin Tianyao Pharmaceuticals Co., Ltd. is engaged in focused amino acid therapy. As pharmaceutical companies turn to customized medical nutrition, L-Threonine applications in therapeutics and clinical formulation will increase significantly.
Regulatory Compliance and Quality Certification Strategies
With tightening regulatory measures worldwide, manufacturers of threonine acid are investing heavily in quality control and certifications to have high standards within the market. Evonik Industries and Ajinomoto Co., Inc. have focused on Good Manufacturing Practices (GMP), ISO 9001, and FDA clearance, adhering to global food and pharmaceutical safety standards.
With consumer confidence becoming a differentiator, producers are using openness in sourcing, production, and testing procedures to gain credibility. Apart from this, Kyowa Hakko Bio Co., Ltd. also has a traceability system, which monitors all the threonine production chain to ensure cleanliness in compliance with clean-label principles.
The high demand for threonine based on non-GMO, free-from allergen, and humanely sourced elements is pushing players to acquire halal and organic certifications to get into premium as well as specialist dietary segments. With regulations pertaining to amino acids becoming stricter, players with efficient compliance systems shall have a better market advantage.
The Global Threonine Acids Industry is on a solid growth path, with driving forces being its widening applications in animal nutrition, pharmaceutical, and functional food industries.
Animal nutrition remains the predominant driver, and L-Threonine is a key amino acid supplement to animal feed for poultry, swine, and aquaculture. With increasing demand for high-performance livestock nutrition, Evonik Industries and Ajinomoto Co., Inc. have both expanded capacity to produce a consistent quantity of feed-grade threonine.
The trend towards low-protein diets in animal production, prompted by sustainability issues, has also increased the demand for threonine as a protein efficiency promoter, maximizing feed conversion rates while minimizing nitrogen excretion.
The pharma industry has also fueled market development, with Mitsubishi Tanabe Pharma Corporation and SIGMA TAU Pharmaceuticals incorporating L-Threonine into liver function therapy, metabolic disorder therapies, and neurological supplements. As increasing research supports the immune system modulating and muscle repair role of threonine, application of the ingredient in medical nutrition and clinical practice is expanding.
Concurrently, the market for functional foods and sports nutrition is emerging as a high-growth segment. Plant-based threonine is being added by firms such as Kyowa Hakko Bio Co., Ltd. and Summit Ingredients in vegan protein powders and performance nutritional products. As consumer interests are being steered towards natural, allergen-free, and sustainable protein sources, plant-based threonine is assuming the role of a lead functional ingredient for future food innovations.
The future period will witness more sophisticated biotechnological developments in threonine production via fermentation, spearheaded by Shanghai Kyowa Amino Acid Co., Ltd. and Tianjin Tianyao Pharmaceuticals Co., Ltd. These will propel cost-effectiveness, scalability, and higher purity of amino acids, further solidifying threonine as a major ingredient in pharmaceutical, human, and animal nutrition sectors.
Ajinomoto Co., Inc., Evonik Industries, and Kyowa Hakko Bio Co., Ltd. lead in the Tier 1 category and account for the largest share in the global supply of threonine acids. They possess high-end fermentation production units, thereby facilitating them to produce high-quality, cost-effective threonine suitable for pharmaceutical, animal feed, and food use. Its ability to expand the size in scale and provide long-term deals for supply to global feed suppliers and drug companies continues to have its market lead.
For example, Evonik Industries has recently expanded its amino acid production plants in Europe and North America, strengthening its feed-grade L-Threonine supply chain stability.
This section includes Mitsubishi Tanabe Pharma Corporation, AMINO GmbH, and Summit Ingredients, and they specialize in threonine specialty formulations for clinical nutrition, food supplements, and precision animal feeding. They are on the small but high-value side, serving high-end pharmaceutical and functional food industries.
Mitsubishi Tanabe Pharma Corporation, for instance, produced high-purity L-Threonine for metabolic disorder treatment by leveraging the market for clinical-grade amino acids. Tier 2 players constitute the middle segment between mass production (Tier 1) and specialty formulation (Tier 3), competing frequently with targeted innovation and local distribution initiatives.
The Tier 3 division includes Shanghai Kyowa Amino Acid Co., Ltd., Tianjin Tianyao Pharmaceuticals Co., Ltd., and Yangzhou Gami Biochem Co., Ltd., which have mainly targeted regional demand and niche applications. The companies produce tailor-made threonine blends used in animal feed, pet food, and small pharmaceuticals for emerging markets and specialty dietary uses.
Shanghai Kyowa Amino Acid Co., Ltd. recently picked up steam by manufacturing customized threonine products for pet nutrition, capturing the trend towards pet wellness and high-end pet food additives.
The following table shows the estimated growth rates of the top five territories.
| Countries | CAGR 2025 to 2035 |
|---|---|
| USA | 4.2% |
| Germany | 4.4% |
| China | 5.6% |
| Japan | 5.2% |
| India | 6.1% |
The United States is seeing a strong growth in threonine acids consumption, fueled by demand for high-efficiency animal feed, sports nutrition, and pharmaceutical uses. Companies like Evonik Industries and Ajinomoto Co., Inc. have introduced accurate feed solutions, optimizing protein use in pig and poultry farming. In the functional nutrition sector, increased consumption of muscle recovery and intestinal well-being supplements is fuelling threonine supplementation in sports nutrition products.
Summit Ingredients and Kyowa Hakko Bio Co., Ltd. are leading the charge, supplying high-purity threonine to supplement makers. On its part, meanwhile, the drug industry is creating new applications of threonine in metabolic and neurological therapy with Mitsubishi Tanabe Pharma Corporation having developed L-Threonine-derived drugs for liver well-being.
Government regulatory promotion of sustainable alternative proteins further powers innovation with American agricultural policies favouring amino acid-based nutrition of livestock. Increasing demand across the feed, food, and drug industries has America set to become a prominent threonine acid applications market.
China is the world's largest producer and consumer of L-Threonine, and its animal husbandry industry, drug technology industry, and functional foods industry are driving the momentum. As more pigs and poultry are raised, the need for effective feed formulation has never been so vast.
The Chinese government actively promotes biotechnology and amino acid manufacturing, and the production of L-Threonine is being promoted through fermentation. Tianjin Tianyao Pharmaceuticals Co., Ltd. has been supported by the government to increase its capacity for amino acid production facilities, confirming China's dominance in threonine supply as an international market.
China's pharmaceutical industry is adding threonine to liver function and metabolic well-being formulation treatments, and Mitsubishi Tanabe Pharma Corporation and Summit Ingredients produce clinical-grade threonine applications. Besides, Chinese manufacturers are also diversifying their global supply chain, exporting threonine to Europe and North America, further solidifying China's position as a dominant force in the global threonine market.
India's livestock industry is increasingly embracing L-Threonine, fueled by increasing poultry and dairy production. The trend towards economical and high-efficiency feed formulation is driving demand for amino acid-based nutrition.
Firms such as Yangzhou Gami Biochem Co., Ltd. and AMINO GmbH are growing distribution networks in India, riding on low-cost production and growing demand for feed industries. The sports nutrition and nutraceutical segment is booming, with Indian consumers increasingly turning to health-conscious, protein-rich foods.
Kyowa Hakko Bio Co., Ltd. and Summit Ingredients are offering plant-based threonine for use in vegan protein supplements, riding India's trends for plant-based dieting. Second, pharmaceutical uses are on the upsurge with Mitsubishi Tanabe Pharma Corporation working with L-Threonine in metabolic and neurology treatments. High-quality low-cost amino acid preparations are seeing demand drive up the production in quantity and refining networks of supply.
| Segment | Value Share (2025) |
|---|---|
| L-Threonine (By Product Type) | 80.0% |
L-Threonine is a leading product form in the threonine acids market, serving a vital role in precision animal nutrition, pharmaceuticals, and plant-based functional food development. Its high bioavailability and essential amino acid nature make it unavoidable in poultry, swine, and aquaculture feed.
Evonik Industries and Ajinomoto Co., Inc. have heavily invested in the production of L-Threonine through fermentation, increasing purity and sustainability. Advanced microbial fermentation techniques with Corynebacterium glutamicum have reduced the cost of production while improving the efficiency of amino acid yield.
L-Threonine is also gaining traction in functional and medical nutrition, with Mitsubishi Tanabe Pharma Corporation, among others, incorporating it into therapeutic preparations for liver function and metabolic health. The sports nutrition market is meanwhile incorporating L-Threonine into plant protein supplements, with a focus on vegan and allergen-free nutritional solutions.
| Segment | Value Share (2025) |
|---|---|
| Animal Feed (By End Use) | 65.0% |
Expanding demand for good feed nutrition is driving worldwide usage of threonine in aqua, pig, and poultry feeds. L-Threonine is a prime functional protein ingredient in protein enhancement and nitrogen usage, enabling farmers to remain one step ahead of feed costs with optimal livestock wellness.
Increased poultry and swine production are a result of increasing livestock operations in China, India, and the USA, which calls for higher demand for amino acid-enhanced feed. Regulatory shifts towards low-protein feeding and low-nitrogen emission policies push the use of threonine further as governments are moving towards encouraging sustainable livestock farming.
With aquaculture gaining momentum globally, high-protein efficiency formulation of feed is giving further boost to L-Threonine's market leadership in livestock nutrition. With long-term collaborations among amino acid producers and feed companies, the animal feed sector is well positioned for long-term growth, and L-Threonine becomes a prime feed ingredient in contemporary livestock nutrition.
Threonine acid markets are also subject to tough competition, as leading producers take innovation-based approaches, capacity expansions, and long-term alliances in a bid to maintain market share. Market leaders such as Evonik Industries and Ajinomoto Co., Inc. dominate the markets through biotechnology techniques in the production of fermentative L-Threonine in a quest for higher efficiency and sustainability.
Whereas Kyowa Hakko Bio Co., Ltd. and Mitsubishi Tanabe Pharma Corporation are applying clinical-grade L-Threonine forms for drug establishment and medical nutritional uses.
Mid-sized players such as Summit Ingredients and Yangzhou Gami Biochem Co., Ltd. are moving into regional livestock feed and functional food sectors with tailored threonine forms for poultry, swine, and plant-based protein supplements. Shanghai Kyowa Amino Acid Co., Ltd. is also venturing into pet nutrition, supplying tailored L-Threonine blends for pet animals.
Increasing regulatory pressure to offer clean-label and sustainable protein sources is encouraging manufacturers to obtain GMP, ISO, and non-GMO certifications to leverage, as companies such as Tianjin Tianyao Pharmaceuticals Co., Ltd. are improving their export capability globally.
For instance
As per product type, the industry has been categorized into D-Threonine, L-Threonine, and Others.
This segment is further categorized into Food Dietary Supplements, Animal Feed, Pharmaceuticals, and Others.
This segment is further categorized into Animal Based, and Plant-Based.
Industry analysis has been carried out in key countries of North America, Latin America, Western Europe, Eastern Europe, Balkans & Baltic, Russia & Belarus, Central Asia, East Asia, South Asia & Pacific, and the Middle East & Africa.
The market is expanding due to rising demand in animal feed, functional food, and pharmaceutical industries, along with advancements in fermentation-based production.
The animal feed sector dominates, accounting for 65% of total market demand, followed by pharmaceuticals (20%) and functional food applications (10%).
Evonik Industries, Ajinomoto Co., Inc., Kyowa Hakko Bio Co., Ltd., Mitsubishi Tanabe Pharma Corporation, and Summit Ingredients are key global players.
L-Threonine is essential for protein metabolism, gut health, and immune function in poultry, swine, and aquaculture, reducing nitrogen waste and feed costs.
Leading manufacturers are investing in biotechnology-driven fermentation techniques, securing ISO, GMP, and non-GMO certifications, and integrating low-carbon manufacturing to meet sustainability goals.
Threonine Acids Market
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