Cell culture refers to a process that allows cells procured from living organisms and tissues to grow outside their natural environment. Considered a remarkable advancement in the field of life sciences, the cell culture is a crucial process aiding in storing and reproducing cells obtained from animals, humans, and plants, which are then used in studies and research purposes.
On these lines, cell culture media refers to the artificial environment in which the cells - such as mesenchymal cells, plant cells, insect cells, and bacterial cells, among others - grow in isolation. Cell culture media is designed to provide the required sources of energy to maintain the atmosphere to aid the life cycle of cells.
Generally, cell culture media offers the vital elements required for cell culture in the incubation environment such as amino acids, vitamins, inorganic salts, glucose, serum, etc. It also provides additional supplementary reagents and sera such as growth hormones, lipids, trace elements, and minerals.
On this premise, cell culture medial bags have emerged as an essential biopharmaceutical element aiding in applications such as expansion, storage, and concentration of cell culture mediums. Furthermore, cell culture media bags are available in a wide range of sizes, thereby making them suitable for adoption in diverse applications.
The growth of the market is majorly driven by the emergence of advanced cell culture techniques and the subsequent demand for cell culture media bags. Moreover, the surging adoption in biopharmaceutical research and development activities will continue to drive the growth of the cell culture media bags market.
Availability of Disposable Bags
Over the years, the trend of disposable materials has penetrated the biopharmaceutical material production landscape and the global cell culture media bags market is no different. Owing to the advantages associated with disposable bags such as reduced cost in product cleaning validation, product usage, reduced cost for the production facility, and low contamination risks, market players are focusing on increasing their production.
Likewise, cell culture media bags are suitable for niche applications such as sterile expansion or differentiation and are ideal for the expansion of cells or the generation of dendritic cells (DCs) from monocytes. Manufacturers are producing cell culture media bags that are gas-permeable and transparent to facilitate effective usage and microscopy.
For instance, Miltenyi Biotec’s line of MACS GMP cell expansion bags offer compartmentalization and allow the volume of cell culture to grow in direct proportion to the growing number of cells. Hence, when the number of cells increases during the process, the bag automatically fits the volume, eliminating the need to change the bag.
As researchers and laboratories continually work on minimizing their spending on resources, expandable bags have emerged as an ideal solution. Demand for automated cell culture systems has also witnessed a spike.
Increasing Adoption as Packaging Material
In addition to storing cell cultures in laboratories and biopharmaceutical industries, cell culture media bags are gaining prominence as a packaging material, thereby opening new growth avenues for players operating in the market.
On the back of benefits associated with the cell culture media bags such as lightweight, high performance, high barrier, and low contamination, they have become a fitting substitute to existing packaging materials in the biopharmaceutical industry. Moreover, since they are designed to isolate the procured cells, they allow complete sealing preventing exposure to the outside environment.
Owing to this ability, cell culture media bags are being primarily used in long-term storage and transportation applications. Furthermore, backed by its portability and compact nature, packaging using cell culture media bags is quite easier to handle as compared to other modes of packaging, thus further pushing the adoption.
Similarly, usage in processing and storage applications will continue to impel revenue to the market players for the years to come. Likewise, increasing focus and investments in cancer research and the rising prominence of gene therapies have also been identified as crucial growth drivers.
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Efficiency Remains Subject of Debate
Although cell culture media bags have become an industry standard for numerous applications, certain challenges continue to challenge the adoption. On these lines, a study claimed that cell culture bags do not offer complete isolation raising questions regarding their ability to reduce contamination. The study also claimed that a certain kind of cell culture media bags are vulnerable to the penetration of external environmental constituents.
Moreover, commercially available cell culture media bags are being used by isolation centers for shipping, and cell culture media bags are not designed specifically to store culture or for shipping activities. Likewise, the high cost of cell culture media is, in turn, hampering the sales of cell culture media bags.
On the other hand, when not manufactured using the right raw materials, cell culture media bags are vulnerable to physical drawbacks, such as propensity for puncture and contamination during tissue transfer. Such shortcomings are expected to hinder the growth of the market to an extent.
North America Cell Culture Media Bags Market
North America, led by the US, is poised to remain the largest regional market for cell culture media bags, capturing nearly half of the global revenue. The region's dominance is majorly attributed to the presence of a flourishing pharmaceutical industry and the spending capacity of end-users on advanced technologies in the region.
For years, the US has remained a center for advancements related to life sciences such as gene expression, vaccines, disease research, etc. According to the Research America organization, the US spent over $158.7 Bn on research and development of novel medical and healthcare providers during the year 2015, registering a significant upsurge from the previous decade.
Moreover, the spending on healthcare is only expected to rise in the forthcoming years, and this will reflect in the cell culture media as well, subsequently driving demand for cell culture media bags to cater to the growing number of activities. On the back of these factors, North America will continue to spearhead the regional landscape through the forecast period.
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East Asia Cell Culture Media Bags Market
East Asia, forefronted by China, is projected to prevail as the second most lucrative regional market, backed by mounting expenditure on healthcare. While the US continues to prevail as the largest spender on medical research, China is swiftly catching up with the former, owing to increased emphasis on medical research.
The growth of the market in this region is also influenced by macro factors such as the growing pharmaceutical industry, increasing number of biopharmaceutical drugs in the pipeline, soaring prevalence of cancer and infectious diseases, and widening base of geriatric population.
The aforementioned factors call for advanced treatment and research techniques, creating inclination towards cell culture, thereby propelling demand for cell culture media bags.
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Europe Cell Culture Media Bags Market
Europe is forecasted to remain a prominent region for the cell culture media bags market owing to rising emphasis by both government and private organizations on research related to chronic diseases. Likewise, increased focus by private organizations is expected to remain a crucial macro factor influencing the growth of the market.
For instance, medical research charities like Cancer Research invest around £1.9 billion annually in the research of cancer and other diseases. Backed by the growing burden of chronic diseases and technological advancements in the preclinical and clinical segment, cell culture has emerged as an ideal solution to alleviate impact in the long run.
The aforementioned factors are expected to give a boost to the market in the region in the years to come.
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Very Large Bags Remain Most Sought
Based on the size of bags, very large bags (>3000 ml) are expected to remain the most sought-out owing to low rates of contamination and the high volume of culture they facilitate for storing. Likewise, very small bags (<150 ml) and small bags (151 - 500 ml) will cumulatively account for over 1/3rd volume of sales.
2D Bag Designs Remain Most Popular
By design, the 2D design segment is expected to capture the lion's share in market value, owing to the high flexibility and total content recovery they offer. Furthermore, 2D bags are ready to use in a wide range of biopharmaceutical applications such as formulation, sampling, and storage of sterile solutions, thereby giving it an edge over its counterpart, 3D design bags.
Bacterial Cells Drive Majority of Demand
Based on host cells, the bacterial cells segment is poised to remain the dominant region through the assessment period, owing to the growing focus on research to find cure several infectious diseases caused by bacteria.
In a similar vein, plant cells are expected to remain the second most lucrative host cell, accounting for over a quarter of the global value.
Biopharmaceutical Manufacturers Channels Majority of Revenue
The biopharmaceutical manufacturers segment is forecasted to channel the majority of revenue, accounting for more than 2/3rds of market value. The dominance of the segment is attributed to the growing usage of single-use technology coupled with an increasing number of regulatory approvals for the usage of cell-culture media bags in the sector.
Cell Culture Media Bags Market Competitive Landscape
Market players are focusing on upscaling the production of media bags to cater to the growing demand for bioprocess production activities. Moreover, manufacturers are addressing challenges and advanced characteristics of bags as four-layered films that offer better oxygen and moisture barriers to the properties.
Moreover, market players are focusing on developing products for specific end-uses. On these lines, in April 2019, Thermo Fisher Scientific launched a new immunoassay - CEDIA Mitragynine (Kratom) Assay - for kratom alkaloid mitragynine screening solely for criminal justice and forensic applications. Continual product innovations will continue to shape the competitive landscape of the market through the forecast period.
Cell Culture Media Bags Market Report: Scope
Historical Data Available for
USD Million for value and units for volume
Key Regions Covered
North America, Europe, East Asia, Latin America, South Asia, Oceania, and Middle East and Africa (MEA)
Key Countries Covered
US, Canada, Brazil, Mexico, Rest of Latin America, Germany, Italy, France, Spain, U.K., Russia, BENELUX, Rest of Europe, India, China, Japan, South Korea, ASEAN, Oceania, Rest of South Asia & Pacific, GCC Countries, Turkey, South Africa, Northern Africa, and Rest of MEA
Key Segments Covered
Bag size, Bag design, Application, Host cell, End-use, and Region
Key Companies Profiled
Parker Hannifin Corp, Pall Corporation, Sartorious AG, Thermo Fisher Scientific Inc., and GE Healthcare Inc. and among others.
Market Forecast, brand share analysis, competition intelligence, DROT analysis, Market Dynamics and Challenges, Strategic Growth Initiatives
Customization & Pricing
Key Questions Answered by the Report
- What is the market size of the cell culture media bags market?
The global cell culture media bags market is expected to reach a valuation of US$ 2.67 Bn by 2030.
- Which is the largest market for cell culture media bags?
US will remain the largest market for cell culture media bags globally.
- Which are the top companies manufacturing cell culture media bags?
Key players manufacturing cell culture media bags include Parker Hannifin Corp, Pall Corporation, Sartorious AG, Thermo Fisher Scientific Inc., and GE Healthcare Inc. and among others.
- In which industry are cell culture media bags used the most?
Cell culture media bags are majorly used by biopharmaceutical manufacturers and in life sciences R&D.
- What is the long-term growth outlook of the cell culture media bags market?
The cell culture media bags market is set for healthy growth in the years to come owing to the growing demand for disposable packaging solutions.
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- Very Small Bags (< 150 ml)
- Small Bags (151 - 500 ml)
- Medium Sized Bags (501 - 1000 ml)
- Large Bags (1001- 3000 ml)
- Very Large Bags (>3000 ml)
- Gas exchanges
- Heat Transfer
- Flow Rate Monitoring
- Mesenchymal Cells
- Plant Cells
- Insect Cells
- Bacteria Cells
- Yeast Cells
- Chinese Hamster Ovary
- Baby Hamster Kidney
- Life Science R&D
- Biopharmaceutical Manufacturers
- North America
- Latin America
- South Asia
- East Asia
- Middle East and Africa