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Difficult-to-Express Proteins Market

Market Insights on Difficult-to-Express Proteins covering sales outlook, demand forecast & up-to-date key trends

Difficult-to-Express Proteins Market By Protein (Proteases, Kinases, Membrane Proteins, Others), Technology Type (Cell-free Protein Synthesis, Prokaryotic Expression Systems, SUMO Fusion System, Gene Fusion Systems), Application (Drug Discovery, Protein Purification, Protein Therapeutics, Disease Diagnostics, Monitoring) & Region - Forecast 2022-2032

Difficult-to-Express Proteins Market Overview

The difficult-to-express proteins market is likely to register a CAGR of 11.33% during the forecast period, and is anticipated to reach a market share of US$ 12.37 Bn in 2032, from US$ 3.8 Bn in 2021, due to development of new tools and significantly boost the overall revenue.

Attributes

Details

Difficult-To-Express Proteins Market CAGR

11.33%

Difficult-To-Express Proteins Market Size (2021)

US$ 3.8 Bn

Difficult-To-Express Proteins Market Size (2032)

US$ 12.37 Bn

The production of complicated therapies requires the use of recombinant proteins, which is a significant sector in the pharmaceutical industry. In heterologous expression systems, many proteins are difficult to express, stumbling the demand for difficult-to-express proteins.

Furthermore, the target protein's inherent features provide difficulties for the expression host, impacting the sales of difficult-to-express proteins. For example, a protein with several membrane spanning domains that may or may not enter into the heterologous host's membrane bilayers, or a protein that cannot be produced in a soluble form.

Many proteins require post-translational modifications that may or may not be present in each host, influencing the difficult-to-express proteins market.

Increasing toolbox to approach the production and purification of difficult-to-express proteins to fulfill the demand for difficult-to-express proteins, which include different expression systems, promoters which have different strengths, cultivation media and conditions.

In addition, development of other microbial cell factories towards their use as effective protein production platforms is expected to spur the global sales of difficult-to-express proteins.

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What Contributes to the Growth of the Difficult-To-Express Proteins Market?

Low protein yields have important industrial ramifications, especially as the need for recombinant proteins in cells grows. The development of new tools for better difficult-to-express proteins market share will greatly increase the overall sales of difficult-to-express proteins.

Development of innovative cell-free protein synthesis platforms based on the industrial workhorse CHO cells that address the difficulties that continue to drive the demand for difficult-to-express proteins.

Prokaryotic expression systems will continue to play an essential role as a cost-effective, customizable, and simple to run source of recombinant protein as the number of authorized therapeutic proteins grows, encouraging the sales of difficult-to-express proteins.

What are the Restraining Factors in the Difficult-To-Express Proteins Market?

However, some obstacles that may limit the demand for difficult-to-express proteins include the high cost of systems and the difficulty of analyzing the target end user segment, as systems for difficult-to-express proteins are confined to end users.

Sabyasachi Ghosh
Principal Consultant
LinkedIn
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Which is the Key Region in the Difficult-To-Express Proteins Market?

Due to increased research and development, collaboration between pharmaceutical firms and university research institutes for the development of novel tools and technologies, North America is likely to contribute significant difficult-to-express proteins market share.

The sales of difficult-to-express proteins will be boosted by increasing research in the field of protein expression and the adoption of new techniques for various diagnostic purposes. The demand for difficult-to-express proteins in Asia Pacific is primarily driven by factors such as the growing presence of large biotechnology and biomedical businesses in the region.

Europe is predicted to account for the second highest proportion of the global difficult-to-express proteins market share, with significant sales of difficult-to-express proteins, due to increased government and non-government investment, as well as the rising prevalence of chronic diseases that require therapeutic treatment.

The difficult-to-express proteins market is being boosted by rising adoption and awareness, as well as the utilization of new and improved technology.

Due to an increase in well-established healthcare facilities and the manufacturing of revolutionary technology, China is projected to see a substantial rise in demand for difficult-to-express proteins. The difficult-to-express proteins market in Latin America, the Middle East and Africa is projected to slow.

What is the Competitive Outlook of the Difficult-To-Express Proteins Market?

Some of the key players present in the global difficult-to-express proteins market are R&D Systems, LifeSensors Inc, Sino Biological, Thermo Fisher Scientific, Enzo Life Sciences, StressMarq Biosciences, Lucigen among others, holding a substantial difficult-to-express proteins market share.

  • Catalent unveiled its new OneBio Suite for the integrated research, manufacture, and clinical supply of biologics in May of this year. One Bio would help address the issues that biologic development businesses face when trying to get programs to the clinic or market faster, or when they need more simplicity in the development process, such as fewer internal resource requirements and a lower risk of redo.
  • The companies are entering into collaborations, mergers, licensing agreements, strategic partnerships, and acquisitions to increase sales of difficult-to-express proteins and their expansion across the globe.
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Report Scope

Report Attribute

Details

Growth rate

CAGR of 11.33% from 2022 to 2032

Base year for estimation

2021

Historical data

2015 - 2020

Forecast period

2022 - 2032

Quantitative units

Revenue in USD billion, volume in kilotons, and CAGR from 2022 to 2032

Report coverage

Revenue forecast, volume forecast, company ranking, competitive landscape, growth factors, and trends, Pricing Analysis

Segments covered

Protein, technology type, end user, application, region

Regional scope

North America; Western Europe, Eastern Europe, Middle East, Africa, ASEAN, South Asia, Rest of Asia, Australia and New Zealand

Country scope

U.S.; Canada; Mexico; Germany; U.K.; France; Italy; Spain; Russia; Belgium; Poland; Czech Republic; China; India; Japan; Australia; Brazil; Argentina; Colombia; Saudi Arabia; UAE; Iran; South Africa

Key companies profiled

R&D Systems, Enzo Life Sciences, Sino Biological, Thermo Fisher Scientific, StressMarq Biosciences, LifeSensors Inc., Lucigen among others

Customization scope

Free report customization (equivalent to up to 8 analysts working days) with purchase. Addition or alteration to country, regional & segment scope.

Pricing and purchase options

Avail customized purchase options to meet your exact research needs.

Frequently Asked Questions

The difficult-to-express proteins market is anticipated to register a CAGR of 11.33% during the forecast period.

The difficult-to-express proteins market share is anticipated to reach US$ 12.37 Bn in 2032.

Demand for difficult-to-express proteins is likely to rise, due to development of new tools and significantly boost the overall revenue.

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Sabyasachi Ghosh
Principal Consultant
LinkedIn
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Find your sweet spots for generating winning opportunities in this market.

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Difficult-to-Express Proteins Market