The global DKK-1 biomarker market is projected to grow from USD 148.6 million in 2025 to USD 348.1 million by 2035, at a CAGR of 8.9%. By biomarker type, serum DKK-1 assays will lead with a 38.4% market share, while by application, oncology diagnosis will dominate with a 29.4% share in 2025.