DNA Synthesis Market Outlook

The DNA synthesis market is projected to be valued at USD 2,898.3 million in 2023 and is expected to rise to USD 9,999.6 million by 2033. The sales of DNA synthesis are expected to record a significant CAGR of 13.2% during the forecast period.

DNA synthesis is the natural creation of nucleic acid strands through DNA replication. Artificially, they are synthesized using genetic engineering and enzyme chemistry in the laboratory for various applications such as therapeutic, diagnostics, and academic and industrial research. These applications are rising with the adoption of DNA synthesis in recent years.

Different companies' DNA synthesis services vary greatly by the cost per base pair, error rates, lengths, throughput, etc. DNA synthesis also includes oligonucleotide and gene synthesis, which have various end-use industries. Some are agricultural science, food science, antibody discovery, immunology, cancer research, infectious disease, and synthetic biology. These industries are boosting the DNA synthesis market growth during the forecast period.

In recent years, gene synthesis has advanced with innovations in DNA as a data storage device and re-engineered genomes. Next-generation gene synthesis provides highly accurate constructs in greater numbers and at comparatively lower prices than possible.

Attribute Details
DNA Synthesis Market Estimated Size (2023) USD 2,898.3 million
DNA Synthesis Market CAGR (2023 to 2033) 13.2%
DNA Synthesis Market Forecasted Size (2033) USD 9,999.6 million

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Factors Influencing the DNA Synthesis Market

The rise in the adoption of gene therapy has enhanced the requirement for rapid gene synthesis products, which provide error-free gene sequences in less time. It improves the body's ability, which helps to fight against the disease.

The adoption of DNA synthesis is essential to avoid any alteration to DNA, which may bring on oncological diseases, including cancer. The demand for DNA synthesis is increasing to repair the disease of premature aging.

The synthetic biology segment is a key dominating segment that drives the DNA synthesis market share. Moreover, increasing R&D associated with gene synthesis coupled with continuous improvement in the technological processes.

Such as molecular separation and protein purification technology, which helps in developing reliable, fast, and cost-effective solutions. These processes are the prominent drivers in the DNA synthesis market growth.

Factors Hindering the DNA Synthesis Market

Long approval times for gene synthesizers and products synthesized may hamper the market growth. On the contrary, the ethical issues associated with genetic engineering are one of the key factors expected to inhibit the growth of the DNA synthesis market over the analysis period.

Moreover, currently, available methods are inconsistent with drawbacks such as high error rate, low yield, and lack of scalability on the gene size are expected to hinder market growth.

Sabyasachi Ghosh
Sabyasachi Ghosh

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Category-wise Insights of DNA Synthesis

Research and Development are Pivotal in the DNA Synthesis Market, Holding a Notable Share of 41.7% overall

Advancing technologies, customization, and specialization needs, the discovery of new applications, therapeutic development, collaboration with academic institutions, and regulatory compliance drove substantial R&D investments.

These efforts were crucial in driving innovation, expanding the applications of synthetic DNA, and meeting the evolving demands of various industries such as biotechnology and pharmaceuticals. R&D was expected to remain a key driver in the DNA synthesis market's growth and development.

Biopharmaceuticals have a Prominent Share of 44.2% in the DNA Synthesis Market

This was attributed to the increasing focus on developing biologics, including monoclonal antibodies and gene therapies, which heavily relied on synthetic DNA constructs for their production.

Biopharmaceutical companies were exploring personalized medicine and gene therapy applications, driving the demand for precise and reliable DNA synthesis. Additionally, DNA synthesis played a crucial role in the development and manufacturing of DNA vaccines used for immune response stimulation. The reliance of biopharmaceuticals on synthetic DNA contributed to their notable presence in the DNA synthesis market.

Regional Analysis

Study of North America DNA Synthesis Market

In terms of regional platform, the market is segmented into North America, Europe, Latin America, Asia Pacific, & the Middle East and Africa. North America holds the largest share in the DNA synthesis market by a surge at over 41.0% share during the forecast period. North America dominates the market owing to increasing gene therapy-based medications during the forecast period.

Highlighting Achievement in the European DNA Synthesis

According to FMI, Europe is expected to provide immense growth opportunities for DNA Synthesis and reach a high share of 31.4% during the forecast period. Europe is expected to witness significant market growth, attributed to the increasing research and development for gene synthesis used in vaccine preparation.

India’s Stand in the DNA Synthesis Market

India is set to be a lucrative market globally, witnessing a transformative growth of 18.1%. The country's biotechnology and life sciences sectors were driving demand for synthetic DNA in various applications, including genetic research, drug development, and personalized medicine. India's biotech startup ecosystem, government initiatives, cost-effective services, and access to a skilled workforce were significant contributors to the market's expansion.

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Start-ups in the DNA Synthesis Market

The start-ups are a new achievement in the medical field, bringing solutions to improve patients' health. Some start-ups are innovating various procedures which improve DNA synthesis-related diseases.

Siolta Therapeutics is a United States-based start-up that develops therapeutic microbial consortia to treat inflammatory diseases, including Rheumatoid arthritis. The start-up provides oral supplements with rational designs and analyses clinical data. ATMC-103H is an investigation process in which the patient is treated for asthma & inflammatory diseases.

Genesis is a Canadian start-up that adopts synthetic biology to transform waste into highly useful material. The company redirects waste food and uses bacteria to decompose it. Further, this solution serves agriculture, textiles, and other sectors to replace plastic with these alternatives.

Competitive Landscape

Experts in the DNA Synthesis Market

The key players are taking the business to another height by contributing their efforts. These players are well-known exceptional leaders who adopt various marketing plans to acquire maximum revenue. Through partnerships, collaborations, and other methods, these marketing experts are growing the market in recent years.

Recent Developments in DNA Synthesis

In March 2021, Aldevron expanded its manufacturing facility at Madison. At this new facility, the company is scaling up the manufacturing of gene synthesis products and ground-breaking therapies, among others. The company has expanded its product manufacturing and boosted the project scope and scale through this expansion.

In February 2018, Twist Bioscience expanded its presence in North America by opening a new office in San Diego, California. The company has adopted this initiative to scale up the manufacturing of synthetic gene constructs and DNA constructs. This expansion allowed the company to design, validate, and provide on-demand orders to customers.

Scope of the Report

Attribute Details
Growth Rate CAGR of 13.2% from 2023 to 2033
Base Year of Estimation 2023
Historical Data 2018 to 2022
Forecast Period 2023 to 2033
Quantitative Units Revenue in USD million and Volume in Units and F-CAGR from 2023 to 2033
Report Coverage Revenue Forecast, Volume Forecast, Company Ranking, Competitive Landscape, growth factors, Trends, and Pricing Analysis
Key Segments Covered Application, End User, Service Type, By Region
Regions Covered North America; Latin America; Europe; East Asia; South Asia; The Middle East & Africa; Oceania
Key Countries Profiled The United States, Canada, Brazil, Mexico, Germany, Italy, France, The United Kingdom, Spain, Russia, China, Japan, India, GCC Countries, Australia
Key Companies Profiled Brooks Automation, Inc. (GENEWIZ); Boster Biological Technology; ProteoGenix; Biomatik; ProMab Biotechnologies, Inc; Thermo Fisher Scientific, Inc; Integrated DNA Technologies, Inc; OriGene Technologies, Inc
Customization & Pricing Available upon Request

Key Segments Covered in the Market Report

By Service Type:

  • Oligonucleotide
  • Universal Oligonucleotide
  • Custom Oligonucleotide
  • Gene
  • Custom Gene
  • Gene Library

By Application:

  • Research and Development
  • Academic Applications
  • Industrial Applications
  • Diagnosis
  • Therapeutics

By End User:

  • Biopharmaceutical Companies
  • Academic and Research Institutes
  • Contract Research Organizations

By Region:

  • North America
  • Latin America
  • Western Europe
  • Eastern Europe
  • Asia Pacific Excluding Japan (APEJ)
  • Japan
  • The Middle East & Africa (MEA)

Frequently Asked Questions

How much will DNA Synthesis Grow until 2033?

The market is expected to reach USD 9,999.6 million by 2033.

What is Driving DNA Synthesis Market Growth?

Increasing convenience food demand drives market growth.

Which Country Dominates the Market?

A market rate of 18.1% is projected for India through 2033.

Who are the Key Manufacturers?

Biomatik and Brooks Automation, Inc. are the key manufacturers.

What is the most Promising Market Segment for DNA Synthesis?

A prominent 44.2% share of the market is held by biopharmaceutical companies.

Table of Content
  • 1. Executive Summary
  • 2. Market Overview
  • 3. Market Background
  • 4. Global Market Analysis 2018 to 2022 and Forecast, 2023 to 2033
  • 5. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Service Type
    • 5.1. Oligonucleotide
    • 5.2. Universal Oligonucleotide
    • 5.3. Custom Oligonucleotide
    • 5.4. Gene
    • 5.5. Custom Gene
    • 5.6. Gene Library
  • 6. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Application
    • 6.1. Research and Development
    • 6.2. Academic Applications
    • 6.3. Industrial Applications
    • 6.4. Diagnosis
    • 6.5. Therapeutics
  • 7. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By End User
    • 7.1. Biopharmaceutical Companies
    • 7.2. Academic and Research Institutes
    • 7.3. Contract Research Organizations
  • 8. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Region
    • 8.1. North America
    • 8.2. Latin America
    • 8.3. Western Europe
    • 8.4. Eastern Europe
    • 8.5. South Asia and Pacific
    • 8.6. East Asia
    • 8.7. Middle East and Africa
  • 9. North America Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
  • 10. Latin America Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
  • 11. Western Europe Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
  • 12. Eastern Europe Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
  • 13. South Asia and Pacific Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
  • 14. East Asia Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
  • 15. Middle East and Africa Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
  • 16. Key Countries Market Analysis
  • 17. Market Structure Analysis
  • 18. Competition Analysis
    • 18.1. Brooks Automation, Inc. (GENEWIZ)
    • 18.2. Boster Biological Technology
    • 18.3. ProteoGenix
    • 18.4. Biomatik
    • 18.5. ProMab Biotechnologies, Inc
    • 18.6. Thermo Fisher Scientific, Inc
    • 18.7. Integrated DNA Technologies, Inc
    • 18.8. OriGene Technologies, Inc
    • 18.9. Quintara Biosciences
    • 18.10. Eurogentec
  • 19. Assumptions & Acronyms Used
  • 20. Research Methodology
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