DNA synthesis market will expand significantly through the next ten years because it produces artificial DNA sequences that serve genetic research together with biotechnology applications and diagnostic procedures and therapeutic interventions.
Between 2025 and 2035 DNA Synthesis market value is estimated to increase from USD 3.7 billion to USD 13.7 billion at a 14% annual growth rate.
The production of synthetic DNA sequences through DNA synthesis techniques enables advancement in gene therapeutic practices and molecular diagnostic approaches and personalized medicine developments. The DNA synthesis market has strong prospects for growth because of rising demands for genetic testing alongside precision medicine.
New DNA synthesis platforms along with automated systems and decreasing synthesis expenses will drive the market into increased expansion and advancement.
Market Metrics
| Metric | Value |
|---|---|
| Market Size (2025E) | USD 3.7 Billion |
| Market Value (2035F) | USD 13.7 Billion |
| CAGR (2025 to 2035) | 14% |
The DNA synthesis market in North America operates as the largest market because of mounting genetic disease cases and rising personal healthcare needs and advances in biotechnology. The biotechnology sector of the United States coupled with its substantial genomic research funding positions it as the market leader.
Burnham Initiative funding for genomic projects and enhancements in precision medication serve as government catalysts that boost the DNA synthesis market throughout this geographical area.
Europe controls a significant portion of the DNA synthesis market because of its constant progress in healthcare research and innovation. The market experiences growth because scientific genomics activities and rising genetic therapy clinical trials contribute to its development.
The DNA synthesis market expands mainly through the UK along with Germany and France in Europe. The market will expand because of genomic research government backing and regulatory advancements combined with increasing need for genetic diagnostics and personal therapies.
High growth will also be in the market for DNA synthesis in the Asia-Pacific region. This is mainly because more attention is being focused on healthcare infrastructure improvement, which provides better access to genomic technologies, as well as the increasing incidence of genetic disorders.
The countries expected to highly drive this particular market in this region are China, Japan, and India. Other determinants for this are rapid innovations in biotechnology, increased government spending towards healthcare innovations, and growing awareness for personalised medicine.
High Cost of DNA Synthesis
The costs are heavily inhibiting potential growth of market for DNA synthesis, especially with large-scale, custom, or high-complexity synthesis. Costs of synthesis have decreased over the years, yet the costs involved in synthetic biology and gene-editing technologies still remain a hindrance for some research institutions and smaller biotech firms to engage.
Development of economically viable options for enlarging the market area, especially in the developing sector, is the need of the hour.
Advancements in Automation and Precision Medicine
Better technologies also put a lot of advantages across the market, such as the automation of DNA synthesis and improved methods for synthesis. By facilitating growth in demand for DNA synthesis services, next-generation sequencing (NGS) technologies are likely to be integrated with DNA synthesis platforms.
The emergence of gene therapies and personalized medicine in increasing numbers since last year has turned out to be a very good growth opportunity for DNA synthesis, with an expected central role in these treatments.
The DNA synthesis market will flourish and expand with considerable leaps from 2025 to 2035 because of the arising need for synthetic biology, improvements in genomics research, personalization in medicine, and further applications in genetic engineering.
Some factors driving further growth in this market are growing applications of gene editing tools such as CRISPR/Cas9, advancements in next-generation sequencing (NGS), expansion of biopharmaceutical production applications as well, and driving demand in synthetic DNA-in drug development, bioprocessing, gene therapy, and agriculture.
The increasing interest in synthetic biology has also been accelerated by the COVID-19 pandemic with regards to applications in diagnostics, vaccines, and therapeutics-development stimulating continuous research and investment beyond the pandemic period.
Market Shifts: 2020 to 2024 vs. 2025 to 2035
| Key Dimensions | 2020 to 2024 |
|---|---|
| Market Size | USD 3.8 Billion to USD 5.4 Billion |
| Growth Drivers | Advancements in gene editing technologies, rising demand for synthetic biology |
| Technology Trends | Oligonucleotide synthesis, solid-phase synthesis |
| Applications | Drug discovery, diagnostics, research, gene therapy |
| End-User Adoption | Academia, biotech firms, pharmaceutical companies |
| Geographic Demand | North America, Europe |
| Regulatory Landscape | Focus on product safety and efficacy |
| Innovation Focus | Synthesis of custom genes, oligonucleotides |
| Supply Chain Dynamics | Centralized manufacturing in North America and Europe |
| Key Dimensions | 2025 to 2035 |
|---|---|
| Market Size | USD 5.4 Billion to over USD 15 Billion |
| Growth Drivers | Expanding applications in gene therapies, vaccines, agricultural biotechnologies |
| Technology Trends | High-throughput synthesis, automation, enzymatic synthesis, next- gen sequencing support |
| Applications | Personalized medicine, regenerative medicine, agricultural biotechnology |
| End-User Adoption | Healthcare providers, precision medicine developers, agricultural firms |
| Geographic Demand | Asia-Pacific, North America, expanding interest in Latin America and Europe |
| Regulatory Landscape | Stricter regulations on genetic modifications, gene therapies, and environmental impacts |
| Innovation Focus | Bio-manufacturing for large-scale gene synthesis, automation in production |
| Supply Chain Dynamics | Global supply chains, including manufacturing facilities in Asia and emerging regions |
The United States market for DNA synthesis is achieving some remarkable statistics with the growth seen due to advancements in genomic research, biotechnology applications, and personalized medicine. The country's inherent strength in holding key players in biotechnology and pharmaceuticals, along with the vast investments made in research and development, contributes mainly to the expansion of the market.
Alongside these, the increasing applications of DNA synthesis for drug discovery, synthetic biology, and diagnostics have also turned the market toward growth.
| Country | CAGR (2025 to 2035) |
|---|---|
| United States | 14.0% |
Market for DNA synthesis in the UK is growing steadily due to the country's commitment to genetics research, as well as the rapidly diversifying applications for DNA synthesis in health care and diagnostics. All this adds to the impetus for this market growth, which finds a welcome set of factors to support it within a strong biotech industry backed by the government in terms of funding for genetic and biomedical research and development.
Demand for DNA synthesis services is expected to be further fueled by the emergence of genome editing technologies like CRISPR.
| Country | CAGR (2025 to 2035) |
|---|---|
| United Kingdom | 13.5% |
Under constant expansion owing to the increasing genomic research and biotechnology industries, DNA synthesis market in the European Union is witnessing manifold growth opportunities. Strategic investments by the EU in genomics, coupled with soaring demand for synthetic biology, genetic testing, and manufacturing, fuel the growth of this market. German, French, and Dutch leadership in the market emanates from their strong biotech and pharmaceutical sectors.
| Country | CAGR (2025 to 2035) |
|---|---|
| European Union | 14.2% |
With significant advances in genomic medicine, bioengineering, and drug development, the DNA synthesis market in Japan is now experiencing rapid growth. Research and development are strong in Japan, where great attention is being paid to biotechnology and wherein growing demand for precision medicine will positively drive growth. Also, Japan's active participation in international genomic research programs is further creating a ripple effect for the adoption of DNA synthesis technologies.
| Country | CAGR (2025 to 2035) |
|---|---|
| Japan | 13.8% |
Due to the rapid growth of biotechnology, increased funding of genetic research, and personalized healthcare, South Korea's DNA synthesis market is witnessing very high growth. The government policies that promote biotech innovations and ramp up clinical research infrastructure have additionally cemented the demand for DNA synthesis technologies.
| Country | CAGR (2025 to 2035) |
|---|---|
| South Korea | 14.1% |
The DNA synthesis market is going to experience huge growth from 2025 to 2035 owing to the marvellous progress that has been made in genetic research, biotechnology, and personalized medicine. The synthesis of DNA is essential for gene synthesis, genetic engineering, and developing novel therapeutic remedies.
The evolving market has a wide variety of applications-from academic research to industrial and clinical uses-prompted by growing demand for oligonucleotides, genes, and gene libraries.
Custom Oligonucleotide Service to Lead the Market
| Service Type | Market Share |
|---|---|
| Custom Oligonucleotide | 47.2% |
Custom Oligonucleotide service will drive the market for DNA Synthesis, expected to account for 47.2% of the total market by 2025. Custom oligos are required for applications such as PCR (polymerase chain reaction), gene expression studies, and synthetic biology. As genomic research becomes more personalized and complex, the demand for customized DNA sequences suited specifically to the research increases.
Aspects like more personalization in medicine, genomic examination, and a range of advancements seen in gene-editing technologies like CRISPR are contributing more toward the demand for custom oligonucleotides. Over and above that, the increased applications of oligonucleotides in diagnostics, vaccines, and therapeutics drive this element's progress further.
Research and Development to Hold the Largest Share
| Application | Market Share |
|---|---|
| Research and Development | 54.6% |
In actual practice, the biggest proportion to be won is expected to be by Research and Development as much as 54.6%. DNA synthesis is thereby the backbone of Research and Development in several fields, amongst which include molecular biology, genetics, and biopharmaceutical development. The increasing number of research projects in genomics, biotechnology, and personalized medicine offer bases for stimulus towards growth.
The huge investments made in genomic research, coupled with rising applications of DNA synthesis in drug discovery, diagnostics, and disease modelling are the two foremost factors driving the R&D sector. Furthermore, advances in the fields of gene therapy, cancer research, and regenerative medicine also result in increased demand for DNA synthesis services.
The DNA synthesis market is likely to grow specifically from 2025 to 2035, driven by advancements in genetic science, the boosting demand for custom DNA sequences, and the rising applications in gene therapy, diagnostics, and synthetic genetics. DNA synthesis plays a critical role in various fields, such as genomics, pharmaceutical inquiry, agriculture, and personalized medicine, which further encourages market enlargement.
Market Share Analysis by Company
| Company Name | Estimated Market Share (%) |
|---|---|
| Thermo Fisher Scientific | 25-30% |
| Integrated DNA Technologies | 20-25% |
| GenScript Biotech Corporation | 15-20% |
| Eurofins Genomics | 10-15% |
| Other Companies (combined) | 25-30% |
| Company Name | Key Offerings/Activities |
|---|---|
| Thermo Fisher Scientific | In 2024, Thermo Fisher launched an advanced high-throughput DNA synthesis platform that increases synthesis speed and accuracy. In 2025, it plans to enhance its platform with automated sequence verification and error correction features. |
| Integrated DNA Technologies | Integrated DNA Technologies introduced a new line of high-quality custom oligonucleotides in 2024, focusing on applications in gene editing and drug development. In 2025, the company will release a product that integrates RNA synthesis with DNA synthesis for more versatile applications. |
| GenScript Biotech Corporation | GenScript launched an advanced DNA assembly platform in 2024 that allows for the creation of large synthetic genes at lower costs. The company plans to integrate CRISPR-based tools in 2025 to optimize DNA editing and delivery. |
| Eurofins Genomics | Eurofins Genomics introduced a new service in 2024 for high-throughput, large-scale DNA synthesis, focusing on precision medicine and biotechnology applications. It plans to introduce customized gene synthesis solutions in 2025 for personalized therapeutics. |
Key Company Insights
Thermo Fisher Scientific (25-30%)
Thermo Fisher maintains a strong position with its cutting-edge DNA synthesis platforms that cater to large-scale applications in genomics, pharmaceutical development, and synthetic biology. Its integration with next-gen sequencing solutions strengthens its market share and appeal to researchers and clinical applications.
Integrated DNA Technologies (20-25%)
Integrated DNA Technologies is renowned for its comprehensive offering of custom oligonucleotides and its specialization in high-precision synthesis for genetic engineering, CRISPR applications, and vaccine development. Its established presence in gene editing and biomanufacturing sets it apart in the market.
GenScript Biotech Corporation (15-20%)
GenScript has established a strong reputation in the synthetic biology space, offering advanced DNA synthesis services and products for gene therapy, vaccine development, and synthetic organism creation. Its focus on innovation in cost-effective solutions positions it well for future growth.
Eurofins Genomics (10-15%)
Eurofins Genomics' extensive oligonucleotide production and custom DNA synthesis services are highly regarded in both research and clinical diagnostics. Its expansion into personalized therapeutics and the growing demand for genomic data further strengthens its market position.
Other Key Players (25-30% Combined)
The overall market size for the DNA synthesis market was USD 3.7 billion in 2025.
The market is expected to reach USD 13.7 billion in 2035.
The demand for DNA synthesis will be driven by advancements in genomics research, increasing applications in personalized medicine.
The top 5 contributing countries are the United States, Germany, China, Japan, and the United Kingdom.
The custom DNA synthesis segment is expected to lead the market due to its widespread use in research, diagnostics, and therapeutic applications.
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DNA Synthesis Market
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