Lupus anticoagulants (LA) are antibodies directed against phospholipid-binding proteins that prolong phospholipid-dependent coagulation assays. Lupus anticoagulant testing is a special blood test to find out if certain antibodies or proteins that cause blood-clotting disorders are present.
Persistent lupus anticoagulant testing positivity is a risk factor for the occurrence and recurrence of venous/arterial thromboembolism and/or pregnancy morbidity and qualifies the patient for lupus anticoagulant testing. The antibodies to be tested are present in about 2-4% of the general population and may develop in people with no known risk factors.
Initial lupus anticoagulant testing typically involves one or more tests that depend on phospholipid-containing reagents, usually partial thromboplastin time (PTT), the LA-sensitive PTT (known as PTT-LA) or dilute Russell viper venom test (DRVVT). The undiagnosed patients are at a constant risk of developing antiphospholipid syndrome, a disease that provokes blood clots in arteries and veins.
Recurrent thrombosis in patients with blood disorders is expected to rise the demand for lupus anticoagulant testing. According to NIH, it is estimated that 20 percent of individuals younger than age 50 who have a stroke have antiphospholipid syndrome which would rise the size of lupus anticoagulant testing market with rising awareness.
Blood disorders like anemia and bleeding disorders such as hemophilia, blood clots, and blood cancers such as leukemia, lymphoma, and myeloma are on rise. Von Willebrand disease (VWD) is a bleeding disorder in which blood doesn’t clot properly.
Between 2012 and 2016, more than 14,600 men, women, and children were seen at hemophilia treatment centers for treatment of VWD in the U.S which is expected to increase the demand for lupus anticoagulant testing. The number of traumatic injuries and wounds are on a rise which could be a reason for rising number of lupus anticoagulant testing done annually to confirm blood disorders.
The lupus anticoagulant testing market is structured differently depending on the regions. North America and Europe has a number of diagnostic laboratories to avail for lupus anticoagulant testing. On the other hand, the existence of the condition is not known.
The dependence on hospitals for primary blood related disorders in remote rural areas in Asia-Pacific and African countries is not observed in the developed lupus anticoagulant testing markets. Blood clots observed in patients with blood related cancers such as leukemia, lymphoma, and myeloma are expected to fuel the demand for lupus anticoagulant testing.
Globally, North America is anticipated to be the largest contributor of lupus anticoagulant testing market. Increase in epidemics related to bleeding disorders in low-income countries contribute to the lupus anticoagulant testing market. East and South Asia is anticipated to be the second largest market in lupus anticoagulant testing.
Europe will also contribute generously to lupus anticoagulant testing market with rising healthcare spending on diseases related to lupus anticoagulant testing market. Middle East & Africa lupus anticoagulant testing market growth is hindered due to high poverty in the region coupled with lower GDP to healthcare spending ratio and lack of healthcare infrastructure.
Some of the key players present in global lupus anticoagulant testing market include Becton Dickinson, Abbott, AstraZeneca plc, F. Hoffmann-La Roche Ltd, Vertex Pharmaceuticals Inc, Novartis AG, Boehringer Ingelheim GmbH, Mylan N.V. and leading diagnostic laboratories within respective countries. With active mergers and acquisitions, the lupus anticoagulant testing market is changing the structure and presence of various small players active in the lupus anticoagulant testing market.
The report is a compilation of first-hand information, qualitative and quantitative assessment by industry analysts, inputs from industry experts and industry participants across the value chain. The report provides in-depth analysis of parent market trends, macroeconomic indicators and governing factors along with market attractiveness as per segments. The report also maps the qualitative impact of various market factors on market segments and geographies.
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