The cold-chain antifreeze glycols market is projected to grow from USD 2.0 billion in 2026 to USD 4.5 billion by 2036, at a CAGR of 8.4%. Monoethylene Glycol (MEG) will dominate with a 39.4% market share, while cold‑chain transport refrigeration will lead the application segment with a 42.3% share.