Amniotic membrane is the innermost layer of the placenta. Amniotic membrane transplantation (AMT) long being practiced in the ophthalmic surgery is emerging as a popular technique, due to recent developments in tissue preservation methods. Amniotic membrane has anti-inflammatory and anti-scarring effects. The growth factors present in the amniotic membrane promotes the epithelial wound healing of the surface of the eye.
Amniotic membrane transplant is a better alternative for corneal and conjunctival reconstruction. The different ophthalmic disorders, such as persistent epithelial defects of cornea, mucous membrane disorders, and chemical burns, among others, are poised to be significant clinical challenges. Amniotic fluid transplantation technique, however, has brought revolutionary changes in reconstructive surgery of the eyes.
Market Value and Forecast
FMI estimates that the global market for amniotic membrane is expected to be valued at US$ 2,322.6 Mn by 2028 end, expanding at an impressive CAGR of 9.3% over 2018–2028. The cryopreserved amniotic membrane segment is expected to dominate the global market with above 70% revenue share in 2017. North America is expected to expand at higher single digit CAGR over the forecast period.
The global amniotic membrane market is expected to be driven by rise in the number of geriatric population, expansion of indications of amniotic membrane transplant, increased R&D investment in AMT by the key players, increasing focus on tissue – cell & stem cell research, unmet clinical needs, regulatory harmonization, etc. Besides, the increase in number of amniotic membrane transplants is likely influenced by introduction of distinctive surgical placenta-derived amniotic membrane transplant techniques, growing awareness regarding presence of growth factors and cytokines in amniotic membrane, and the demographic change constituting aging of the population.
Moreover, the process of product approvals has been accelerating in the developed markets. Fast FDA approvals for amniotic membrane-based products such as suspensions and allografts to treat surgical wounds is contributing to the growth of the amniotic membrane market. However, the lack of skilled/experienced professionals to perform AMT and lack of standardized guidelines on tissue and bio-medical engineering are factors hampering the growth of the market.
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Market Segmentation by Application
Based on treatment, the global amniotic membrane market has been segmented into,
- Surgical Wound
Surgical wound application segment in amniotic membrane market dominated the global market in 2018 and is expected to follow the same trend during forecast period. Over 6.5 million patients in U.S. suffer with chronic wounds annually, out of which around 200,000 patients are treated using skin or dermal substitutes. Also, chronic wound market in U.S. alone offers a revenue opportunity of around US$ 3.0 Billion. Whereas, ophthalmology segment accounts for the second largest revenue share in global amniotic membrane market on the account of increased capability of amniotic membrane to enhance epithelial wound healing of the surface of the eye.
The global market for amniotic membrane is segmented in to eight key regions viz. North America, Latin America, Western Europe, Eastern Europe, Asia Pacific excluding Japan & China (APECJ), Japan, the Middle East and Africa (MEA) and China. North America accounted a high share of over 40% in 2017. APEJ is expected to witness double digit growth due to rising number of AMT procedures in India and China.
The global market for amniotic membrane is highly consolidated with top 5 players contributing over 65% revenue share in the global market. Examples of the key players identified in the global amniotic membrane market are Integra LifeSciences Inc., MiMedx Group, Inc., Alliqua BioMedical, Inc., Skye Biologics Inc., Katena Products, Inc., Tissue-Tech Inc., Amnio Technology, LLC, Applied Biologics LLC, Human Regenerative Technologies, LLC, etc.
The Global Amniotic Membrane Market has been Segmented Based on:
- Product Type
- End User
The report analyses the global amniotic membrane market in terms of value (US$ Mn). The report begins with the market definition and explaining different types of amniotic membrane types available in the market. This section also provides an overview on dermal substitute market, to which amniotic membrane is a sub-part. The market view point section includes FMI’s analysis on key trends, drivers, opportunities and macro factors influencing the global market. Opportunity analysis provided in the section allows to better equip with crystal clear decision-making insights. Pipeline analysis provided in the subsequent section helps to identify future rivals in the global market.
The report analyses the market based on regions and presents the forecast in terms of value (US$ Mn) for the next 10 years. The regions covered in the report include:
- North America
- Latin America
- Western Europe
- Eastern Europe
- Asia Pacific Excluding Japan & China (APEJC)
- The Middle East and Africa (MEA)
The next section of report analyses the market based on product types and forecast is provided in terms of value for the next 10 years. The product types covered in the report include:
- Cryopreserved Amniotic Membrane
- Lyophilized Amniotic Membrane
The next section of the report provides analysis based on application and the forecast is provided in terms of value for the next 10 years. The applications covered in the report include:
- Surgical Wound
The next section of report analyses the market based on the end users of amniotic membrane products and provides the forecast in terms of value for the next 10 years. End users covered in the report include:
- Specialized Clinics
- Ambulatory Surgical Centres
- Academic Research Centres