Cryopreservation for In-vitro Fertilization (IVF) Market

2020 Analysis and Review: Cryopreservation for In-vitro Fertilization (IVF) Market by Application – Oocyte, Sperm, and Embryo for 2020-2030

Introduction

The global cryopreservation for in-vitro fertilization (IVF) market is likely to grow steadily with substantial improvements to pregnancy success rates in long term storage for reproductive materials. Favorable changes in regulations toward single parents, same sex couples, and older couples will create opportunities.

According to analysis by Future Market Insights (FMI), cryopreservation for IVF market surpassed a valuation of US$ 339 million in 2019. The market is set to reflect an impressive 10.2% CAGR through 2030.

Adoption for Assisted Reproductive Technology

Stronger adoption of assisted reproductive technology and developments of novel cryopreservation methods are bolstering therapeutic applications in the IVF industry.

Cryopreservation of gametes and embryos for bio banks and IVF settings has come out as a viable alternative to conventional practices of using fresh embryos with tech advances in recent years.

Consequently, frozen-thawed embryos have been proven to have a relatively higher success rate as compared to fresh alternatives. Health risks from repeated ovarian stimulation in IVF treatments is also expected to support developments in the market, with higher popularity among older couples.

Vitrification Processes to Gain Ground

Fertility preservation is an essential part of reproductive medicine. The key methods of cryopreservation in IVF are freeze thaw and vitrification. The vitrification process is relatively newer, and avoids the potential pitfall of ice formation that is the freeze-thaw method is prone to.

Also, oocytes are more prone to ice damage owing to a microtubule structure. This will remain a key factor that will drive demand for cryopreservation for the foreseeable future in the industry.

Industry Focus on Female Cancer Patients

With improvements in treatment for malignant tumors, the survival rates of cancer patients have been on the rise. Further, investments into the development techniques for assisted reproduction for patients who have been subjected to cancer and relative treatments is bolstering the case of cryopreservation techniques.

A key challenge is the cryopreservation of ovarian tissue following remission of the disease. Freezing of ovarian tissue allows for higher success rates in pregnancy even after damaging treatments such as chemotherapy. 

Consequently, the sector is expected to generate major lucrative opportunities for market players in the near future.

Key Challenges

Cryogenics in IVF is witnessing increasing demand in the commercial fertility treatments sector. However, a key factor holding back the market is the high costs of cryogenics and IVF treatments.

Also, challenges in terms of ice formation and damage to oocytes, embryos, and sperm remains a problem with conventional cryogenics. Low awareness about cryogenic offerings in developing countries and rural areas are holding back adoption rates in the industry.

Region-wise Analysis

East Asia

East Asia, is the leading regional market for cryogenics in IVF. The region has a massive, fast-growing population, and the costs of fertility treatments are relatively lower. The market is estimated to account for around 30% of the global market share with a valuation surpassing US$ 106 million in 2019.

The lucrative position of East Asia in the cryopreservation for IVF can be attributed to the large numbers of domestic market participants and favorable policies by governments towards fertility treatments.

In addition, the number of ART cycles in the country is growing rapidly. On the other hand, lower awareness in rural areas hurt the prospects of the industry.

China, in particular, has witnessed increased investments into cryogenics, and with a largely aging population, the demand for oocyte, embryo, and sperm storage expected to gain traction.

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Europe

Oocyte preservation is an established and growing practice in Europe. The regional market is second only to East Asia, accounting for over US$ 90 million in 2019. Major investments into viability of egg donation practices. The region has also displayed a higher inclination towards biopsies and cryopreservation of ovarian tissue that contributes to developments in the region.

According to the report on cryopreservation for IVF, the market is also driven by increased spending on public healthcare infrastructure, in addition to strategic investments by public and private bodies towards donor egg banks. Also, Europe is has made strides in regulations towards alternative sexual lifestyles which is contributing to favorable developments in the regional cryopreservation for IVF market.

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Latin America

Latin America is a the fastest growing regional market for cryopreservation for IVF, accounting for ~14% CAGR through the assessment period. While still at a nascent stage, the regional market is largely driven by applications in the research sector.

However, the developments in the market have been significantly hindered by the absence of specialized information on the topic in Spanish. Experts from Argentina, Mexico, Colombia, Bolivia, Cuba, Costa Rica, Peru, Ecuador, and others are major contributors to the publication of literature on the technology. Efforts towards a collaborative network of Latin American experts on the subject are likely to positively influence the market in the near future.

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Category-wise Insights

Higher Demand for Cryopreservation Media

Cryopreservation for IVF products can also be classified in terms of type into cryopreservation media, cryopreservation storage devices, consumables and accessories, and cryo-shipping. The demand for cryopreservation media is projected to remain significantly higher accounting for over 36% of the market share through the forecast period.

The growth of the segment can be largely attributed to increasing adoption rates in terms of assisted reproductive technology (ART), and the growing numbers of infertile couples on a global scale.

Preference for Embryo Cryopreservation

On the basis of application, cryopreservation for IVF is used for embryo, sperm and oocyte preservation. Embryo cryopreservation is expected to display higher market shares, accounting for close to 70% of the overall cryopreservation for IVF market share.

Strong demand for embryo preservation can be largely attributed to advances in technology such as vitrification processes and ovarian stimulation services and products, and the resultant increase in success rates for pregnancies.

IVF Fertility Clinics Drive Demand

Cryogenics for IVF largely finds use in IVF and fertility clinics, research and academic institutes, biobanks, cryo shipping, and cryo monitoring/inventory management. IVF and fertility clinics remain the primary user of cryogenics, with research and academic institutes reflecting strong growth.

The growth of IVF clinics and centers can be attributed to the rapid increase in the number of facilities around the world and adoption of cutting edge tech. Improved access to experts in assisted reproductive services will be major contributors to growth rates for the foreseeable future.

Competitive Landscape

Leading market players in the moderately fragmented cryopreservation for IVF market have been largely focused on investments into product development and launches. Also, market players are also emphasizing on strategic collaborations and the expansion of infrastructure to improve access to consumers.

For instance, in August 2020, Future Fertility, based in Canada launched Violet, a cloud-based software for assessing the probability of oocytes successfully fertilizing prior to being exposed to cryogenic storage processes.

CU Advanced Reproductive Medicine (CU ARM) in December 2019, announced the acquisition of the world’s very first Cryo Sentinel Monitoring system to minimize the risk of storage accidents for eggs, sperm, and embryo, which provides adequate warning in terms of liquid nitrogen depletion.

Extend Fertility has announced the expansion of its fertility portfolio apart from its leading segment of proactive egg freezing. This includes full spectrum in vitro fertilization processes, while also cutting down prices to improve access to consumers.

Such changes in the market are likely to generate major lucrative opportunities for cryopreservation for IVF market participants for the forecast period.

Aside from these market participants, other leading players in the market include:

  • Thermo Fisher Scientific Inc.
  • MilliporeSigma
  • Fujifilm Irvine Scientific Inc.
  • Vitrolife AB
  • Kitazato Corp.
  • Brooks Life Sciences
  • Corning Inc.
  • Bio-Match Tech Ltd.
  • Cryo Solutions B.V.
  • Cryogatt Systems Ltd.
  • Kustodian Ltd.
  • ColdStash
  • TMRW Life Sciences Inc.
  • Vitromed GmbH
  • Cryotech
  • Cook Medical LLC
  • Worthington Industries Inc.

The list is only indicative – full list of intrauterine insemination (IUI) devices market key players is available upon request.

Cryopreservation for IVF Market Report: Scope

Attribute

Details

Forecast Period

2020-2030

Historical Data Available for

2015-2019

Market Analysis

US$ Million for value

Key Regions Covered

North America, Latin America, Europe, South Asia, East Asia, Oceania, and Middle East & Africa (MEA)

Key Countries Covered

US, Canada, Brazil, Mexico, Argentina, Germany, U.K., France, Italy, Spain, BENELUX, Russia, China, Japan, South Korea, India, Thailand, Indonesia, Malaysia, Australia, New Zealand, GCC Countries, Turkey, South Africa

Key Segments Covered

Product Type, Application, End User, and Region

Key Companies Profiled

Thermo Fisher Scientific Inc., Millipore Sigma, Fujifilm Irvine Scientific Inc., Vitrolife AB, Kitazato Corp., Brooks Life Sciences, Corning Inc., Worthington Industries Inc., Cook Medical LLC, Cryotech, Vitromed GmbH, ColdStash, Kustodian Ltd., Cryogatt Systems Ltd., Cryo Solutions B.V. (only indicative list)

Report Coverage

Market Forecast, brand share analysis, competition intelligence, DROT analysis, Market Dynamics and Challenges, Strategic Growth Initiatives

Customization & Pricing

Available upon Request.

Key Questions Answered by the Report

  • What is the size of the cryopreservation for IVF market?

    The global cryopreservation for IVF market reached a valuation of US$ 339.8 million in 2019. The estimated growth rate for the cryopreservation for IVF market will be an impressive 10.2% CAGR between 2020 and 2030.

  • Which is the largest market for cryopreservation for IVF?

    East Asia is projected to be the largest market for cryopreservation for IVF throughout the forecast period, owing to changes in government policy, and increasing cases of infertility the resulting demand and increasing investments into healthcare infrastructure.

  • Which are the top companies in global cryopreservation for IVF market?

    Thermo Fisher Scientific Inc., Millipore Sigma, Fujifilm Irvine Scientific Inc., Vitrolife AB, Kitazato Corp., Brooks Life Sciences, Corning Inc., Worthington Industries Inc., and Cook Medical LLC are among the leading market players.

  • What are the applications of cryopreservation for IVF?

    Cryopreservation for IVF products are largely used in in the preservation of biological reproductive materials including oocytes, embryos, and sperm. This allows greater scope for fertility treatments.

  • In what types are cryopreservation for IVF products available?

    Companies usually manufacture cryopreservation for IVF products in 4 types – media, storage devices, consumables & accessories, and cryo-shipping. The demand for cryopreservation media for IVF is expected to remain relatively stronger that the other segments.

  • What is the near-term competitive outlook of the global cryopreservation for IVF market?

    The global cryopreservation for IVF market is moderately fragmented, with the major presence of mid-size manufacturers, and with product development and strategic collaborations gaining importance in the industry.

Enquiry before Buying

  • Is this research conducted by Future Market Insights?

    Yes, the research has been conducted by expert analysts of Future Market Insights through a combination of primary research and secondary research. To know more about how the research was conducted, you can speak to research analyst.

  • What research methodology is followed by FMI?

    FMI follows a methodology that encompasses demand side assessment of the market, and triangulates the same through supply side analysis. This methodology is based on use of standard market structure, methods and definitions.

  • Who are the respondents for primary research?

    FMI speaks to stakeholders across the spectrum, including C-level executives, distributors, product manufacturers, industry experts. For a full list of primary respondents, please reach out to us.

  • What are the sources of secondary research?

    FMI conducts extensive secondary research through proprietary databases, paid databases, and information available in the public domain. We refer to industry associations, company press releases, annual reports, investor presentations, and research papers. More information about desk research is available upon request

  • Is a sample of this report available for evaluation?

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Key Segments

Product Type

  • Cryopreservation Media
  • Cryopreservation Storage Devices
    • Dewars
    • Cryogenic Liquid Cylinders
    • Cryogenic Storage Tanks
      • Vapor Tanks
      • Storage Alarm Systems
      • LN 2 Auto Fill Systems
      • LN2 Sterilization System
      • Cryo Control/Inventory Management Systems
    • Storage Container
      • Cryocanes
      • Visotubes
      • Cannisters
  • Consumables & Accessories
    • Vitrification Carriers
    • Sperm Straws
    • Saw Freeze Straws
    • Cryovials
  • Cryo-Shipping
    • Dry Shipper Container
    • Clinical Pack Over Wrap
    • Cryogenic Labels

Application

  • Oocycte Cryopreservation
  • Sperm Cryopreservation
  • Embryo Cryopreservation

End User

  • Biobanks
  • IVF & Fertility Clinics
  • Research & Academic Institutes
  • Cryo-shipping/couriers
  • Cryo Monitoring /Inventory Management

Regional Outlook

  • North America (US, Canada)
  • Latin America (Brazil, Mexico, Argentina, Rest of LATAM)
  • Europe (Germany, UK, Russia, France, Italy, Spain, BENELUX, Rest of Europe)
  • South Asia (India, Thailand, Indonesia, Malaysia, Rest of South Asia)
  • East Asia (China, Japan, and South Korea)
  • Oceania (Australia, New Zealand)
  • Middle East & Africa (GCC Countries, Turkey, South Africa, and Rest of MEA)

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