Gene Editing Tools: A Viable Cure for Rare Genetic Disorders
Gene editing tools continue to attract high demand for the treatment of rare genetic disorders such as sickle cell anemia, heart disease, diabetes, Alzheimer's disease, obesity, cancer, and others. In the recent years, manufacturers have renewed their interest in clinical trials to prove the efficiency of gene editing tools in niche application areas, which include veterinary medicine and bioremediation. The growing prevalence of cancer, sickle cell disease, obesity management and Alzheimer's disease is significantly increasing the global demand for gene editing tools.
Gene Editing Tools Market - Key Research Findings
Global gene editing tools market size in 2018 – Nearly US$ 258 Mn
The gene editing tools market is expected to grow at an approximate CAGR of 18% over 2019-2029.
North America and Europe are expected to remain the largest regional markets for gene editing tools
North America and Europe are among the prominent regions in the gene editing tools market on account of the increasing number of clinical trials registered for the development of gene editing tools and increase in the number of patents issued claiming CRISPR/Cas9.
Most well-funded CRISPR companies expected to exploit the growth outlook of the gene editing tools market
Major players in the gene editing tools market, such as Editas Medicine, CRISPR Therapeutics, and Intellia Therapeutics, are collectively receiving a total funding of around US$ 410 Mn. The technology transfer business is seldom highly lucrative.
On an average, the U.S. and European universities receive 3.0% and 1.1% of their research funding budget respectively from the licensing royalties.
However, in case of CRISPR, a number of market players are present who are ready to commercialize their CRISPR technology. The impact of legal cases on all these players at the global level is still unclear.
The CRISPR/Cas9 segment is expected to remain the most preferred product type segment of the gene editing tools market
The growth of this segment can be primarily attributed to the increased demand for CRISPR-based genome editing for the treatment of cancer and sickle cell disease.
Some of the key factors, such as improved efficiency and the increased application of CRISPR in veterinary medicine, are expected to propel the growth of the gene editing tools market.
Top 3 Factors Shaping the Gene Editing Tools Market
Steady Growth of CRISPR Despite NO Patent Grants is the Major Trend in the Gene Editing Tools Market
Usually, venture capitals and the Technology Transfer Offices (TTOs) necessitate a clear and strong Intellectual Property (IPR) position in the market before they make any allegiance to invest funds in any life sciences company. However, no such criteria has been fulfilled in the CRISPR field.
The leading companies or manufacturers in the genetic space, such as Editas Medicine, CRISPR Therapeutics, and Intellia Therapeutics, together resister a combined market capitalization of US$ 4.94 Billion. Moreover, despite the ongoing patent dispute among market players for intellectual rights to gene editing tools, the overall funding received by all the three companies exceeds US$ 396.48 Million.
Introduction of Novel Gene Editing Tools is expected to Generate Significant Opportunities for the Gene Editing Tools Market
Genome editing has proven to be a powerful novel gene makeover tool used to make precise deletions, additions, or alterations to the genome of an organism. The development of novel gene editing tools, which include Transcription Activator-like Effector Nucleases (TALENs), Zinc Finger Nucleases (ZFNs), meganucleases, and the recently introduced CRISPR/Cas9 system, has improved the efficiency, precision, and flexibility of genome editing tools.
Moreover, the availability of these enhanced gene editing tools at a lower price as compared to conventional genome editing techniques has proven to be a significant factor boosting the demand for gene editing tools, thus driving the gene editing tools market.
Growing Demand for Personalized Medicine is Propelling the Demand for Gene Editing Tools
Recent advancements in CRISPR and its ease of use have generated significant interest in the biomedical community. CRISPR-based gene editing has high potential to cater to the therapeutic landscape of induced disorders owing to the presence of key players in the industry, such as Intellia, CRISPR Therapeutics, and Editas, which offer precise gene targeted treatments for β-thalassemia and Sickle Cell Disease (SKD).
Over the next few years, the clinical development of CRISPR-based gene editing technology promises to alter the manner in which monogenic or polygenic diseases are treated, though the research is still in its initial stages, thereby generating more revenues in global gene editing tools market.
Gene Editing Tools Market Structure Analysis
The global gene editing tools market is a fragmented market owing to the presence of a significant number of major market players and regional players
Manufacturers are focusing on receiving patent approval for their CRISPR-based gene editing techniques and ZFN-based gene editing tools for applications such as veterinary medicine and bioremediation in the U.S.
Some of the top manufacturers that contribute a high revenue share in the gene editing tools market are Thermofisher Scientific Inc., CRISPR Therapeutics, Editas Medicine, Intellia Therapeutics Inc., and Merck KGaA
Market Set to Grow 5.4X between 2019 and 2029
The gene editing tools market is estimated to witness a robust growth over the course of the forecast period. The demand for CRISPR/Cas9 gene editing tools will be driven by their ability to improve the efficiency, precision, and flexibility of genome editing tools, and their availability at a lower price as compared to conventional gene editing tools. Furthermore, the potential set of applications for genome editing in the agriculture and animal healthcare sectors is also driving the adoption of gene editing tools.
Emerging Countries Promise New Opportunities of Growth
North America is projected to contribute the highest revenue share in the global gene editing tools market in 2019. However, robust growth is estimated in developing countries, especially Japan, India, and China, on the account of the shift from investments in R&D and technology, particularly in life sciences, from Europe and North America to Asia Pacific. Emerging economies such as India and China have adequate skilled labor and qualified as well as experienced manpower at affordable prices, which increases the scope for outsourcing of biotech projects. Due to China’s sturdy growth, East Asia is likely to emerge as a lucrative market during the forecast period.
The Broader Perspective
Stakeholders in the gene editing tools market are investing in providing gene-editing tools to cater to research requirements, due to which they can expect to witness stable returns. The research area in genomics has witnessed development on the account of progresses in various molecular and in vitro cellular techniques. This development could be achieved if the regulatory oversight is impartial to potential hazards, gaining expansive support from researchers, consumers and commercial interests. R&D investments and funding are expected to continue to grow over the assessment period.
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR/Cas9) gene editing tools remains among the top-selling
CRISPR/Cas9 followed by Zinc Finger Nucleases (ZFNs) gene editing tools likely to grow at the highest rate
Transposon Systems gene editing tools are likely to witness slow adoption
Academic and research institutes remain among the prominent end users with nearly 40% revenue share
Demand from biotech and pharma companies to grow at a rapid rate
How Growth will Unfold
CRISPR/Cas9 gene editing tools are expected to continue to maintain their dominance over other gene editing tools during the assessment period, whereas Zinc Finger Nucleases (ZFNs) are also expected to gain acceptance at a steady pace.
CRISPR/Cas9 | ZFNs | TALENs | Viral Systems | Transposon Systems | Others
* This data is only a representation. Actual data may vary and will be available in report.Click Here To Know How The Growth Will Unfold
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Gene Editing Tools Market: Global Industry Analysis 2014-2018 & Opportunity Assessment 2019-2029
A recent market study published by FMI “Gene Editing Tools Market: Global Industry Analysis 2014-2018 & Forecast 2019-2029” offers a comprehensive assessment of the most important market dynamics. After conducting thorough research on the historic as well as current growth parameters of the gene editing tools market, the growth prospects of the market are obtained with maximum precision.
Gene Editing Tools Market Taxonomy
The global gene editing tools market is segmented in detail to cover every aspect of the market and present a complete market intelligence approach to the reader.
- Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR/Cas9)
- Zinc Finger Nucleases (ZFNs)
- Transcription Activator-Like Effector Nucleases (TALENs)
- Viral Systems
- Transposon Systems
- Veterinary Medicine
- Cell Line Engineering
- Food and Brewing Development
- Food Waste Management
- Bio sensing Development
By End User
- Biotech and Pharma Companies
- Contract Research Organizations
- Academic and Research Institutes
- Food Industry
- North America
- Latin America
- South Asia
- East Asia
- Middle East & Africa
The report commences with the executive summary of the gene editing tools market, which includes a summary of the key findings and key statistics of the market. It also includes the market value (US$ million) estimates of the leading segments of the gene editing tools market.
Readers can find the detailed taxonomy and the definition of the gene editing tools market in this chapter, which will help them understand the basic information about the gene editing tools market. This section also highlights the key inclusions and exclusions, which helps the reader understand the scope of the gene editing tools market report.
The report provides the key trends that are expected to substantially impact the growth of the market during the forecast period. Detailed industry trends are provided in this section, along with key market developments or product innovations, key competition mapping, and veterinary health market outlook, which is likely to have a significant impact on gene editing tools market.
This section includes the key inclusions of the report. It includes the product adoption & usage analysis, product timeline, regulatory assessment, reimbursement scenario, pipeline assessment & opportunity analysis, and manufactures’ strategies for market expansion.
This section explains the global market value analysis and forecast for the gene editing tools market between the forecast period of 2014-2029. This chapter includes the detailed analysis of the historical gene editing tools market, along with an opportunity analysis of the future. Readers can also find the absolute opportunity for the current year (2019 – 2020), and an incremental opportunity for the forecast period (2019 – 2029).
This chapter explains the key macro-economic factors that are expected to influence the growth of the gene editing tools market during the forecast period. Along with macroeconomic factors, this section also highlights the opportunity analysis for the gene editing tools market. This chapter also highlights the key dynamics of the gene editing tools market, which include the drivers, restraints, and trends. Moreover, it will enable readers to understand the key trends followed by the leading manufacturers in the gene editing tools market.
This section explain the global market penetration analysis for the gene editing tools in 2018. The section also covers the key information about the CRISPR patents landscape, regulatory scenario for genome editing, the adoption of CRISPR in veterinary medicine, along with the CRISPER licensing landscape. It also provides information on the penetration of the CRISPR-based gene editing tools market by emerging application areas.
Based on the product type, the gene editing tools market is segmented into Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR/Cas9), Zinc Finger Nucleases (ZFNs), Transcription Activator-Like Effector Nucleases (TALENs), Viral Systems, transposon systems, and other gene editing tools. In this chapter, readers can find information about the key trends and developments in the gene editing tools market and market attractiveness analysis based on the product type.
A detailed analysis about the applications of gene editing tools in the gene editing tools market has been explained in this chapter. The application areas for gene editing tools have been classified into veterinary medicine, cell-line engineering, bioremediation, food & brewing development, food waste management, biosensing development, and others. In this chapter, readers can find information about the market attractive analysis based on application.
This chapter provides details about the gene editing tools market on the basis of end user, based on which the market has been classified into biotech & pharma companies, contract research organizations, academic & research institutes, food industry, and others. In this chapter, readers can understand the market attractiveness analysis based on end user.
This chapter explains how the gene editing tools market will grow across various geographic regions, such as North America, Latin America, Europe, East Asia, South Asia, Oceania, and the Middle East & Africa (MEA).
This chapter includes a detailed analysis of the growth of the North America gene editing tools market, along with a country-wise assessment that includes the U.S. and Canada. Readers can also find the regional trends, regulations, and market growth based on the application, end users, and countries in North America.
Readers can find detailed information about several factors, such as the pricing analysis and the regional trends, which are impacting the growth of the Latin America gene editing tools market. This chapter also includes the growth prospects of the gene editing tools market in the leading LATAM countries such as Brazil, Mexico, Argentina, and the Rest of Latin America.
Important growth prospects of the gene editing tools market based on its end users in several countries, such as Germany, the UK, France, Spain, Italy, Russia, Poland, and the Rest of Europe, are included in this chapter.
India, Indonesia, Thailand, and Malaysia are among the leading countries in the South Asia region, which are among the prime subjects of assessment to obtain the growth prospects of the South Asia gene editing tools market in this chapter. Readers can find detailed information about the growth parameters of the South Asia gene editing tools market during the period 2019-2029.
This chapter highlights the growth of the gene editing tools market in the East Asia by focusing on China, Japan, and South Korea. This section also helps readers understand the key factors that are responsible for the growth of the gene editing tools market in East Asia.
In this chapter, Australia and New Zealand are among the leading countries in the Oceania region, which are the prime subjects of assessment to obtain the growth prospects of the Oceania gene editing tools market.
This chapter provides information about how the gene editing tools market will grow in the major countries in the MEA region, such as GCC Countries, South Africa, Israel, and the rest of MEA, during the forecast period 2019 - 2029.
In this chapter, readers can find detailed information about the tier analysis and market concentration of the key players in the gene editing tools market, along with their market presence analysis by region and product portfolio.
In this chapter, readers can find a comprehensive list of all the leading stakeholders in the gene editing tools market, along with detailed information about each company, which includes the company overview, revenue shares, strategic overview, and recent company developments. Some of the market players featured in the report are Thermo Fisher Scientific Inc., ERS Genomics, CRISPR THERAPEUTICS, Merck KGaA, Editas Medicine, Takara Bio USA, New England Biolabs, Intellia Therapeutics, Inc., and GenScript Biotech Corporation, among others.
This chapter includes a list of acronyms and assumptions that provide a base to the information and statistics included in the gene editing tools market report.
This chapter helps readers understand the research methodology followed to obtain the various conclusions as well as important qualitative and quantitative information about the gene editing tools market.
How the research was conducted?
Primary research interviews with Key opinion leaders and other participants were conducted for data collection and validation of the below information:
- Prevalence of rare genetic disorders
- High prevalence by gender and age-group
- Treatment-seeking rate
- Adoption of gene editing tools as a mode of treatment
- Adoption of gene editing tools in niche application areas
- Average Selling Price (US$) and market growth
- Key developments
- Key trends and opportunities
- Region-wise dynamics
- Reimbursement & patent landscape
- Market share information
- Key brands
- ? Competition & Key Vendor Strategies
- American Sports Medicine Institute
- American Academy of Orthopaedic Surgeons
- The American Orthopaedic Association
- Canadian Orthopaedic Association
- Asia Pacific Orthopaedic Association
- The American Association of Orthopaedic Medicine
- British Orthopaedic Association
- American Orthopaedic Society for Sports Medicine
- Australian Orthopaedic Association
- German Society for Orthopaedics and Trauma
- Chinese Association of Orthopaedic Surgeons
- The Japanese Orthopaedic Association
- National Joint Registry
- ORTHOWORLD INC
- National Center for Biotechnology Information
- Knee Society
- American College of Rheumatology
- ARTHRITIS FOUNDATION
- Annual Reports/SEC filings/Investor Presentations/Earning Call Transcript
- Industry Journals
Primary Interview Splits