NGS Sample Preparation Market Outlook (2022-2032)

[342 Pages Report] The global NGS sample preparation market worth is expected to rise at a CAGR of 13.7% to US$ 5441.1 Million by 2032, supported by:

  • The Rising burden of infectious diseases around the world.
  • The need for an efficient and cost-effective method of detecting rapidly mutating pathogens.
  • Increased government support to handheld the new market players operating in the contagious disease domain.

Given the low cost and great efficiency of sequencing, NGS technologies have displaced conventional sequencing techniques generating higher demand for NSG sample preparation in recent years. NGS has become more affordable thanks to making the human genome accessible at only $1,000, and it is anticipated that the benefits of NGS sample preparation would increase its popularity further.

Rapid advancements in sequencing technology have increased throughput capacities significantly while also lowering costs. For instance, next-generation sequencing (NGS) costs have dropped significantly since the Human Genome Project's conclusion, according to a paper published by Illumina in the year 2021.

As a result of the aforementioned developments, it is projected that the market under study might expand exponentially throughout the course of the investigation. Nonetheless, the rigorous regulations related to NGS sample preparation and the high prices of the equipment are projected to restrain the NGS sample preparation market growth.

Report Attribute Details
NGS Sample Preparation Market Value (2022) US$ 1321.8 Million
NGS Sample Preparation Market Anticipated Forecast Value (2032) US$ 5441.1 Million
NGS Sample Preparation Market Projected Growth Rate (2022 to 2032) 13.7%

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How Market Players have Benefitted and Constrained in the Aftermath of the Pandemic

A remarkable rise in demand for NGS sample preparation was observed during the initial phase of the Covid-19 pandemic, which pushed many countries to accept this technology and encourage capitalists to work on this domain. There was an urgent need for diagnostic tools that may be used at lower costs and yield better findings due to the increased prevalence of Covid-19. So even during the years following the subsidence of pandemic infections, it is observed that the NGS sample preparation business is attracting more participants in order to prevent the development of new virus strains.

Over the past few years, a number of market players in the health sector entered the NGS sample preparation market, making it comparatively more fragmented than before. Later it was found that the sheer amount of regulatory compliances, technological limitations, and infrastructure insufficiency in their target regions made the whole business unfeasible.

So frequent mergers and acquisitions can be observed among the NGS sample preparation market players to get rid of the unsuccessful endeavors, and this trend is anticipated to continue for some more days ahead. For instance, Agilent Technologies purchased Resolution Bioscience in April 2021, a pioneer in the development and marketing of precision cancer solutions based on next-generation sequencing (NGS). The country's studied market is projected to develop faster as a result of these purchases.

However, the said market promises even more opportunities as CFDNA library preparation can reveal info on how to trace down numerous virus transmission pathways throughout the world and can help researchers find viral mutations that may impair the effectiveness of vaccines and the detection process.

Additionally, it is anticipated that greater support from the federal government and commercial businesses, as well as expanded use of NGS technology by state and publicly funded healthcare organizations, would propel market expansion. For example, the Broad Institute of Harvard University and DNA Script Company received nearly US$ 23 Million from the Intelligence Advanced Research Projects Activity in January 2020 in the United States to provide a significant boost to businesses and clinical investigations using NGS as their foundation for innovation.

The adoption of NGS sample preparation is on a rising trajectory as Next Generation Sequencing (NGS) has evolved to be a powerful platform enabling the sequencing of thousands to millions of DNA molecules simultaneously.

In addition, the rising demand for NGS sample preparation is due to its wide range of applications including human whole genome sequencing (WGS), whole exome sequencing, targeted sequencing using panels of a few to thousands of genes, and expression profiling.

NGS has revolutionized the genome sequencing market and increasing need for personalized treatment likely drives the NGS sample preparation market growth during the forecast period.

Increase in the healthcare spending and improvement in the healthcare technology are the major factors anticipated to expand NGS sample preparation market size.

Moreover, the adoption of NGS sample preparation augments to a significant extent owing to the rise in incidence of disease conditions like cancer and use of NGS for diagnostic purpose in cancer and management or treatment of disease. As per the NGS sample preparation market report, single molecule real time sequencing is expected to be fastest growing segment due to real time preparation of samples.

Drug discovery and diagnostic application are expected be highest revenue generating and fastest growing NGS sample preparation segments, improving the overall NGS sample preparation market statistics.

Biopharmaceutical companies are biggest user of NGS samples as these companies are focusing on development of new drugs, in turn, enlarging the NGS sample preparation market share on the whole.

What are Various Factors Spearheading the NGS Sample Preparation Market?

Increasing prevalence of genetic disorders is driving the overall demand for NGS sample preparation.

Furthermore, rising need for the personalized medicines and clinical diagnosis is expected to shape the NGS sample preparation market trends.

The NGS sample preparation market key trends & opportunities are swayed by technological advancements in sample preparation procedures and kits to standardize and simplify steps.

By transitioning from a technology used for research to one used in clinical diagnostics, NGS sample preparation market outlook is going through a significant change.

However, companies, in order to consolidate their market position by expanding the NGS sample preparation market share, must deal with issues related to library preparation and various automation techniques.

NGS is revolutionising agricultural productivity and assisting in the assessment of its impact on air, soil, gut, and water microbiomes, as well as human health, in turn, fostering the NGS sample preparation market trends and forecast.

Moreover, the adoption of NGS sample preparation is also due to the fact that NGS is also assisting in locating the origin of plant diseases and making recommendations for their eradication.

The development of veterinary medicines has been sparked by the NGS-based metagenomic screening which is considered to considerably sway the NGS sample preparation market future trends.

However, the lack of veterinary-specific protocols is hindering the NGS sample preparation market from expanding.

Consequently, players in the market are creating NGS-based protocols for veterinary virology. As a result, businesses are expanding their research into porcine samples that have been contaminated with various DNA and RNA viruses.

Molecular diagnostic tests and devices typically require more time and money to receive FDA approval.

It could be argued that delays in the introduction of new treatments pose a significant barrier to the commercialization of potentially useful tests, in turn, the overall demand for NGS sample preparation.

The European Union (EU), China, and Japan all have regulations that are similar. This negatively impacts the NGS sample preparation adoption trends, ultimately stifling the market for NGS sample preparation.

Sabyasachi Ghosh
Sabyasachi Ghosh

Principal Consultant

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Regional Analysis

How is the North America NGS Sample Preparation Market Evolving?

The presence of major biopharmaceutical companies and technological advancements in North America make it the most alluring region for the NGS sample preparation market.

The NGS sample preparation market share of North America is anticipated to account for 37.6% in 2022.

The significant regional market share can be primarily attributed to the encouraging initiatives by public and private organisations for the development and, the rising number of NGS-based clinical applications in the region.

What is the Growth Outlook for the Europe NGS Sample Preparation Market?

Europe is anticipated to hold a NGS sample preparation market share of 23.8% in 2022 due to the focus of research institutes on development of new methods of NGS sample preparation and aging population.

There is a variation in NGS processes carried out throughout Europe, particularly the absence of bioinformatic analysis standardisation.

To benefit patients, specialised biomedical personnel with the knowledge and abilities necessary to assure the patient that testing is carried out to the highest standard throughout Europe are needed.

Startup Ecosystem

How is the Start-up Ecosystem of the NGS Sample Preparation Market?

A small start-up by the name of SimplSeq believes that its technology will revolutionise sequencing sample preparation and ultimately displace the industry's titans.

The company is currently beta testing a technology that it claims to be faster and simpler than conventional methods and can enable better use of priceless liquid biopsy sample material. It is a spinout of a new tech incubator called Murrieta Genomics.

SimplSeq's founder and CEO, Brandon Young, is also the creator of the patented core technology. He created a technique that eliminates the need for DNA and RNA purification and uses a library.

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How is the Competition Landscape in the NGS Sample Preparation Market?

Some of the market participants in the global NGS sample preparation market is Thermo Fisher Scientific, Agilent Technologies, Inc., F Hoffman-La Roche AG, Illumina, Inc., Eurofins Scientific and Macrogen, Inc.

Companies in the NGS sample preparation market are utilising new opportunities in the areas of agriculture and animal research in addition to medical services to diversify their revenue sources.

In order to better understand multigenic disorders, companies in the market for NGS sample preparation are expanding their studies into the identification of novel disease genes in animals, in turn, expand the NGS sample preparation market share.

A few of the recent developments in NGS sample preparation market are as follows:

  • NGS library preparation systems were introduced by Agilent Technologies and were made to handle difficult DNA sequencing assays.
  • NEBNext Custom RNA Depletion Design Tool and RNA Depletion Core Reagent Set were introduced by New England Biolabs to enable customizable RNA Depletion.

Report Scope

Report Attribute Details
Growth Rate CAGR of 13.7% from 2022 to 2032
Base Year for Estimation 2021
Historical Data 2015 to 2021
Forecast Period 2022 to 2032
Quantitative Units Revenue in USD Million and CAGR from 2022-2032
Report Coverage Revenue Forecast, Volume Forecast, Company Ranking, Competitive Landscape, Growth Factors, Trends and Pricing Analysis
Segments Covered
  • Technology
  • Application
  • End Use
  • Region
Regions Covered
  • North America
  • Latin America
  • Europe
  • Asia Pacific & Japan
  • The Middle East and Africa
Key Countries Profiled
  • USA
  • Canada
  • Brazil
  • Argentina
  • Germany
  • UK
  • France
  • Spain
  • Italy
  • Nordics
  • BENELUX
  • Australia & New Zealand
  • China
  • India
  • ASEAN
  • GCC
  • South Africa
Key Companies Profiled
  • Thermo Fisher Scientific
  • Agilent Technologies, Inc.
  • F Hoffman-La Roche AG
  • Illumina, Inc.
  • Eurofins Scientific
  • Macrogen, Inc.
Customization Available Upon Request

Key Segments Profiled in the NGS Sample Preparation Market Survey

By Type:

  • Sequencing by Synthesis (SBS)
  • Ion Semiconductor Sequencing
  • Single Molecule Real Time (SMRT) Sequencing
  • Nanopore Sequencing

By Application:

  • Diagnostics
  • Drug Discovery
  • Biomarker Discovery
  • Precision Medicine
  • Agriculture and Animal Research
  • Other Application

By End Use:

  • Biopharmaceutical Companies
  • Hospitals
  • Research Institutes
  • CMOs
  • CROs

By Region:

  • North America
  • Latin America
  • Europe
  • Asia Pacific & Japan
  • The Middle East and Africa

Frequently Asked Questions

What is the Growth Outlook for the NGS Sample Preparation Market?

The global NGS sample preparation market is projected to advance at a CAGR of 13.7% during the forecast period.

What is the Anticipated NGS Sample Preparation Market Share of North America?

North America is projected to hold a NGS sample preparation market share of 37.6% in 2022.

What is the Future of the NGS Sample Preparation Market?

The NGS sample preparation market is anticipated to account for US$ 5441.1 million by 2032.

Table of Content
1. Executive Summary

    1.1. Global Market Outlook

    1.2. Demand-side Trends

    1.3. Supply-side Trends

    1.4. Technology Roadmap Analysis

    1.5. Analysis and Recommendations

2. Market Overview

    2.1. Market Coverage / Taxonomy

    2.2. Market Definition / Scope / Limitations

3. Market Background

    3.1. Market Dynamics

        3.1.1. Drivers

        3.1.2. Restraints

        3.1.3. Opportunity 

        3.1.4. Trends

    3.2. Scenario Forecast

        3.2.1. Demand in Optimistic Scenario

        3.2.2. Demand in Likely Scenario

        3.2.3. Demand in Conservative Scenario

    3.3. Opportunity Map Analysis

    3.4. Investment Feasibility Matrix

    3.5. PESTLE and Porter’s Analysis

    3.6. Regulatory Landscape

        3.6.1. By Key Regions

        3.6.2. By Key Countries

    3.7. Regional Parent Market Outlook

4. Global Market Analysis 2017-2021 and Forecast, 2022-2032

    4.1. Historical Market Size Value (US$ Mn) Analysis, 2017-2021

    4.2. Current and Future Market Size Value (US$ Mn) Projections, 2022-2032

        4.2.1. Y-o-Y Growth Trend Analysis

        4.2.2. Absolute $ Opportunity Analysis

5. Global Market Analysis 2017-2021 and Forecast 2022-2032, By Technology

    5.1. Introduction / Key Findings

    5.2. Historical Market Size Value (US$ Mn) Analysis By Technology, 2017-2021

    5.3. Current and Future Market Size Value (US$ Mn) Analysis and Forecast By Technology, 2022-2032

        5.3.1. Sequencing by Synthesis

        5.3.2. Ion Semiconductor Sequencing

        5.3.3. Single Molecule Real Time Sequencing

        5.3.4. Nanopore Sequencing

    5.4. Y-o-Y Growth Trend Analysis By Technology, 2017-2021

    5.5. Absolute $ Opportunity Analysis By Technology, 2022-2032

6. Global Market Analysis 2017-2021 and Forecast 2022-2032, By Application

    6.1. Introduction / Key Findings

    6.2. Historical Market Size Value (US$ Mn) Analysis By Application, 2017-2021

    6.3. Current and Future Market Size Value (US$ Mn) Analysis and Forecast By Application, 2022-2032

        6.3.1. Diagnostics

        6.3.2. Drug Discovery

        6.3.3. Biomarker Discovery

        6.3.4. Precision Medicine

        6.3.5. Agriculture and Animal Research

        6.3.6. Other Applications

    6.4. Y-o-Y Growth Trend Analysis By Application, 2017-2021

    6.5. Absolute $ Opportunity Analysis By Application, 2022-2032

7. Global Market Analysis 2017-2021 and Forecast 2022-2032, By End User

    7.1. Introduction / Key Findings

    7.2. Historical Market Size Value (US$ Mn) Analysis By End User, 2017-2021

    7.3. Current and Future Market Size Value (US$ Mn) Analysis and Forecast By End User, 2022-2032

        7.3.1. Biopharmaceutical Companies

        7.3.2. Hospitals

        7.3.3. Research Institutes

        7.3.4. CMOs

        7.3.5. CROs

    7.4. Y-o-Y Growth Trend Analysis By End User, 2017-2021

    7.5. Absolute $ Opportunity Analysis By End User, 2022-2032

8. Global Market Analysis 2017-2021 and Forecast 2022-2032, By Region

    8.1. Introduction

    8.2. Historical Market Size Value (US$ Mn) Analysis By Region, 2017-2021

    8.3. Current Market Size Value (US$ Mn) Analysis and Forecast By Region, 2022-2032

        8.3.1. North America

        8.3.2. Latin America

        8.3.3. Europe

        8.3.4. Asia Pacific

        8.3.5. MEA

    8.4. Market Attractiveness Analysis By Region

9. North America Market Analysis 2017-2021 and Forecast 2022-2032, By Country

    9.1. Historical Market Size Value (US$ Mn) Trend Analysis By Market Taxonomy, 2017-2021

    9.2. Market Size Value (US$ Mn) Forecast By Market Taxonomy, 2022-2032

        9.2.1. By Country

            9.2.1.1. U.S.

            9.2.1.2. Canada

        9.2.2. By Technology

        9.2.3. By Application

        9.2.4. By End User

    9.3. Market Attractiveness Analysis

        9.3.1. By Country

        9.3.2. By Technology

        9.3.3. By Application

        9.3.4. By End User

    9.4. Key Takeaways

10. Latin America Market Analysis 2017-2021 and Forecast 2022-2032, By Country

    10.1. Historical Market Size Value (US$ Mn) Trend Analysis By Market Taxonomy, 2017-2021

    10.2. Market Size Value (US$ Mn) Forecast By Market Taxonomy, 2022-2032

        10.2.1. By Country

            10.2.1.1. Brazil

            10.2.1.2. Mexico

            10.2.1.3. Rest of Latin America

        10.2.2. By Technology

        10.2.3. By Application

        10.2.4. By End User

    10.3. Market Attractiveness Analysis

        10.3.1. By Country

        10.3.2. By Technology

        10.3.3. By Application

        10.3.4. By End User

    10.4. Key Takeaways

11. Europe Market Analysis 2017-2021 and Forecast 2022-2032, By Country

    11.1. Historical Market Size Value (US$ Mn) Trend Analysis By Market Taxonomy, 2017-2021

    11.2. Market Size Value (US$ Mn) Forecast By Market Taxonomy, 2022-2032

        11.2.1. By Country

            11.2.1.1. Germany

            11.2.1.2. U.K.

            11.2.1.3. France

            11.2.1.4. Spain

            11.2.1.5. Italy

            11.2.1.6. Rest of Europe

        11.2.2. By Technology

        11.2.3. By Application

        11.2.4. By End User

    11.3. Market Attractiveness Analysis

        11.3.1. By Country

        11.3.2. By Technology

        11.3.3. By Application

        11.3.4. By End User

    11.4. Key Takeaways

12. Asia Pacific Market Analysis 2017-2021 and Forecast 2022-2032, By Country

    12.1. Historical Market Size Value (US$ Mn) Trend Analysis By Market Taxonomy, 2017-2021

    12.2. Market Size Value (US$ Mn) Forecast By Market Taxonomy, 2022-2032

        12.2.1. By Country

            12.2.1.1. China

            12.2.1.2. Japan

            12.2.1.3. South Korea

            12.2.1.4. Malaysia

            12.2.1.5. Singapore

            12.2.1.6. Australia

            12.2.1.7. New Zealand

            12.2.1.8. Rest of APAC

        12.2.2. By Technology

        12.2.3. By Application

        12.2.4. By End User

    12.3. Market Attractiveness Analysis

        12.3.1. By Country

        12.3.2. By Technology

        12.3.3. By Application

        12.3.4. By End User

    12.4. Key Takeaways

13. MEA Market Analysis 2017-2021 and Forecast 2022-2032, By Country

    13.1. Historical Market Size Value (US$ Mn) Trend Analysis By Market Taxonomy, 2017-2021

    13.2. Market Size Value (US$ Mn) Forecast By Market Taxonomy, 2022-2032

        13.2.1. By Country

            13.2.1.1. GCC Countries

            13.2.1.2. South Africa

            13.2.1.3. Israel

            13.2.1.4. Rest of MEA

        13.2.2. By Technology

        13.2.3. By Application

        13.2.4. By End User

    13.3. Market Attractiveness Analysis

        13.3.1. By Country

        13.3.2. By Technology

        13.3.3. By Application

        13.3.4. By End User

    13.4. Key Takeaways

14. Key Countries Market Analysis

    14.1. U.S.

        14.1.1. Pricing Analysis

        14.1.2. Market Share Analysis, 2021

            14.1.2.1. By Technology

            14.1.2.2. By Application

            14.1.2.3. By End User

    14.2. Canada

        14.2.1. Pricing Analysis

        14.2.2. Market Share Analysis, 2021

            14.2.2.1. By Technology

            14.2.2.2. By Application

            14.2.2.3. By End User

    14.3. Brazil

        14.3.1. Pricing Analysis

        14.3.2. Market Share Analysis, 2021

            14.3.2.1. By Technology

            14.3.2.2. By Application

            14.3.2.3. By End User

    14.4. Mexico

        14.4.1. Pricing Analysis

        14.4.2. Market Share Analysis, 2021

            14.4.2.1. By Technology

            14.4.2.2. By Application

            14.4.2.3. By End User

    14.5. Germany

        14.5.1. Pricing Analysis

        14.5.2. Market Share Analysis, 2021

            14.5.2.1. By Technology

            14.5.2.2. By Application

            14.5.2.3. By End User

    14.6. U.K.

        14.6.1. Pricing Analysis

        14.6.2. Market Share Analysis, 2021

            14.6.2.1. By Technology

            14.6.2.2. By Application

            14.6.2.3. By End User

    14.7. France

        14.7.1. Pricing Analysis

        14.7.2. Market Share Analysis, 2021

            14.7.2.1. By Technology

            14.7.2.2. By Application

            14.7.2.3. By End User

    14.8. Spain

        14.8.1. Pricing Analysis

        14.8.2. Market Share Analysis, 2021

            14.8.2.1. By Technology

            14.8.2.2. By Application

            14.8.2.3. By End User

    14.9. Italy

        14.9.1. Pricing Analysis

        14.9.2. Market Share Analysis, 2021

            14.9.2.1. By Technology

            14.9.2.2. By Application

            14.9.2.3. By End User

    14.10. China

        14.10.1. Pricing Analysis

        14.10.2. Market Share Analysis, 2021

            14.10.2.1. By Technology

            14.10.2.2. By Application

            14.10.2.3. By End User

    14.11. Japan

        14.11.1. Pricing Analysis

        14.11.2. Market Share Analysis, 2021

            14.11.2.1. By Technology

            14.11.2.2. By Application

            14.11.2.3. By End User

    14.12. South Korea

        14.12.1. Pricing Analysis

        14.12.2. Market Share Analysis, 2021

            14.12.2.1. By Technology

            14.12.2.2. By Application

            14.12.2.3. By End User

    14.13. Malaysia

        14.13.1. Pricing Analysis

        14.13.2. Market Share Analysis, 2021

            14.13.2.1. By Technology

            14.13.2.2. By Application

            14.13.2.3. By End User

    14.14. Singapore

        14.14.1. Pricing Analysis

        14.14.2. Market Share Analysis, 2021

            14.14.2.1. By Technology

            14.14.2.2. By Application

            14.14.2.3. By End User

    14.15. Australia

        14.15.1. Pricing Analysis

        14.15.2. Market Share Analysis, 2021

            14.15.2.1. By Technology

            14.15.2.2. By Application

            14.15.2.3. By End User

    14.16. New Zealand

        14.16.1. Pricing Analysis

        14.16.2. Market Share Analysis, 2021

            14.16.2.1. By Technology

            14.16.2.2. By Application

            14.16.2.3. By End User

    14.17. GCC Countries

        14.17.1. Pricing Analysis

        14.17.2. Market Share Analysis, 2021

            14.17.2.1. By Technology

            14.17.2.2. By Application

            14.17.2.3. By End User

    14.18. South Africa

        14.18.1. Pricing Analysis

        14.18.2. Market Share Analysis, 2021

            14.18.2.1. By Technology

            14.18.2.2. By Application

            14.18.2.3. By End User

    14.19. Israel

        14.19.1. Pricing Analysis

        14.19.2. Market Share Analysis, 2021

            14.19.2.1. By Technology

            14.19.2.2. By Application

            14.19.2.3. By End User

15. Market Structure Analysis

    15.1. Competition Dashboard

    15.2. Competition Benchmarking

    15.3. Market Share Analysis of Top Players

        15.3.1. By Regional

        15.3.2. By Technology

        15.3.3. By Application

        15.3.4. By End User

16. Competition Analysis

    16.1. Competition Deep Dive

        16.1.1. Thermo Fisher Scientific

            16.1.1.1. Overview

            16.1.1.2. Product Portfolio

            16.1.1.3. Profitability by Market Segments

            16.1.1.4. Sales Footprint

            16.1.1.5. Strategy Overview

                16.1.1.5.1. Marketing Strategy

        16.1.2. Agilent Technologies, Inc.

            16.1.2.1. Overview

            16.1.2.2. Product Portfolio

            16.1.2.3. Profitability by Market Segments

            16.1.2.4. Sales Footprint

            16.1.2.5. Strategy Overview

                16.1.2.5.1. Marketing Strategy

        16.1.3. F Hoffman-La Roche AG

            16.1.3.1. Overview

            16.1.3.2. Product Portfolio

            16.1.3.3. Profitability by Market Segments

            16.1.3.4. Sales Footprint

            16.1.3.5. Strategy Overview

                16.1.3.5.1. Marketing Strategy

        16.1.4. Illumina, Inc.

            16.1.4.1. Overview

            16.1.4.2. Product Portfolio

            16.1.4.3. Profitability by Market Segments

            16.1.4.4. Sales Footprint

            16.1.4.5. Strategy Overview

                16.1.4.5.1. Marketing Strategy

        16.1.5. Eurofins Scientific

            16.1.5.1. Overview

            16.1.5.2. Product Portfolio

            16.1.5.3. Profitability by Market Segments

            16.1.5.4. Sales Footprint

            16.1.5.5. Strategy Overview

                16.1.5.5.1. Marketing Strategy

        16.1.6. Macrogen, Inc.

            16.1.6.1. Overview

            16.1.6.2. Product Portfolio

            16.1.6.3. Profitability by Market Segments

            16.1.6.4. Sales Footprint

            16.1.6.5. Strategy Overview

                16.1.6.5.1. Marketing Strategy

17. Assumptions & Acronyms Used

18. Research Methodology

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