Pulmonary Arterial Hypertension Treatment Market

Pulmonary Arterial Hypertension Treatment Market: Lack of Treatment Awareness, Inadequate R&D, & Frequent Drug Rejection Post Clinical Trial to Hamper Growth: Global Industry Analysis 2013 - 2017 and Opportunity Assessment 2018 - 2028

  • 2018-06-15
  • REP-GB-1218
  • 260 pages
  • PDF PPT EXCEL
 Pulmonary Arterial Hypertension Treatment Market

An Incisive, In-depth Analysis on the Pulmonary Arterial Hypertension Treatment Market

This study offers a comprehensive, 360 degree analysis on the Pulmonary Arterial Hypertension Treatment market, bringing to fore insights that can help stakeholders identify the opportunities as well as challenges. It tracks the global Pulmonary Arterial Hypertension Treatment market across key regions, and offers in-depth commentary and accurate quantitative insights. The study also includes incisive competitive landscape analysis, and provides key recommendations to market players on winning imperatives and successful strategies.

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Pulmonary arterial hypertension- commonly known as PAH- is characterized by increased pressure in the pulmonary arteries due to structural changes in blood vessel walls, aggregation of platelets and alteration of smooth muscle cell function- eventually elevating pressure in the pulmonary arteries responsible for pumping blood to the lungs. This eventually leads to right heart failure and, ultimately, death.

According to Centers for Disease Control and Prevention (CDC) and World Health Organization (WHO), the global prevalence of pulmonary arterial hypertension treatment market is projected to be 100,000 – 200,000—which accounts for 15 - 50 patients per million of the population. Expert analysis into the subject has reveals that due to the rarity of the disease and the complexity of diagnosing it, only a small fraction of patients with PAH are being treated. Due to which, the Global Pulmonary Arterial Hypertension Treatment market is anticipated to grow at a sluggish CAGR of 2.5% over the forecast period 2018-2028.

Endothelin Receptor Antagonists (ERAs) to lead the Market among Drugs; SGC Stimulators to Capture Market by the End of 2028 Owing to Drug Effectiveness

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According to expert analysis, the global pulmonary arterial hypertension treatment market is anticipated to grow at a steady rate. Based on drug type, the global pulmonary arterial hypertension treatment market is segmented into vasodilators, Phosphodiesterase 5 (PDE 5) inhibitors, Endothelin receptor Antagonists (ERA), Soluble guanylate cyclase (SGC) stimulator with ERAs accounting for the highest market share in terms of value. However, SGC stimulator drug- is expected to witness relatively higher growth rates in terms of value in the global pulmonary arterial hypertension treatment market, due to its positive results. According to research Riociguat is the first SGC stimulator that has entered clinical development- showing significantly results in treating pulmonary vascular haemodynamics and increases exercise ability in patients with PAH.

Lack of Awareness, Slow Drug R&D, and Unsuccessful Clinical Trials Restraining the Growth of Global Pulmonary Arterial Hypertension Treatment Market

Rising prevalence of pulmonary arterial hypertension has witnessed increased adoption of medicinal treatment of PAH, healthcare spending, rise in awareness, and huge drug pipeline. However, several factors have hampered the growth of global pulmonary arterial hypertension treatment market.

Currently, several forms of medication in the global prevalence of pulmonary arterial hypertension treatment market are adopted by people with PAH, but unfortunately no treatment has significantly improved survival. For instance, Ruvise (imatinib)-used for adults as add-on therapy for the treatment PAH, is continually questioned for its efficacy. Treatment with Ruvise should only be initiated in patients who are not showing signs of rapid disease progression. Ruvise has been studied only in combination with two or more conventional PAH-specific therapies. Efficacy has been shown in patients suffering from idiopathic PAH, heritable PAH and in PAH associated with connective tissue disease. Medical research has also shown an unexplained higher risk of subdural haemorrhage associated with imatinib use.

Additionally, slow productivity of R&D in the global pulmonary arterial hypertension treatment market owing to high diagnosis and treatment cost, termination of drugs by major players during clinical trials, unawareness about presence of pulmonary arterial hypertension among patients are some of the factors which are hampering the growth of this market. Lastly, expiry of patents of major PAH drugs will lead to generic versions of these drugs being sold at 60% to 70% lower prices than that of the present branded drugs- projected to pose a challenge for the growth the global pulmonary arterial hypertension treatment market.

Market experts at Future Market Insights (FMI) offer a 10-year forecast on the global pulmonary arterial hypertension treatment market with a primary objective to offer actionable insights, updates and, information related to market opportunities in the global pulmonary arterial hypertension treatment market- which in terms of revenue is anticipated to grow at a slow CAGR of 2.5% during the forecast period, 2018–2028. Insights on key trends, drivers, restraints, value forecasts and opportunities for companies operating in the global pulmonary arterial hypertension treatment market are explored and presented in the report.

The global market for Pulmonary arterial hypertension treatment market is expected to witness to grow owing to rising prevalence of pulmonary arterial hypertension disease, increasing adoption of treatment and healthcare spending, huge drug pipeline, and external partnerships in research driving new treatment formulations. These factors are also anticipated to give rise to investment opportunities to key players in the global pulmonary arterial hypertension treatment market.

A key feature of this report- mostly overlooked in other reports is the analysis of key segments in terms of absolute dollar opportunity- which is absolutely critical for assessing the level of opportunity that a provider can look to achieve, as well as to identify potential resources from a sales and delivery perspective for services offered by pulmonary arterial hypertension treatment market. To understand key segments in terms of their growth and performance in the global pulmonary arterial hypertension treatment market, FMI has developed a market attractiveness index to help providers identify existing market opportunities.

Revenue from the pulmonary arterial hypertension treatment market in North America is the most dominating due to increase awareness and improvement in healthcare system. To understand and assess opportunities in this market, the report offers the market forecast on the basis of type into the drug type, distribution channel, and regions. The report provides analysis of the global Pulmonary arterial hypertension treatment market in terms of market value (US$ Mn).  

The global pulmonary arterial hypertension treatment market is segmented on the basis of drug type into:

  • Vasodilators

  • Phosphodiesterase 5 (PDE 5) inhibitors

  • Endothelin receptor Antagonists (ERA)

  • Soluble guanylate cyclase (SGC) stimulator

The report also has a ‘market dynamics’ section, wherein FMI’s analysis key trends, drivers, restraints, opportunities and macro-economic factors influencing the growth of the global pulmonary arterial hypertension treatment market.

The report analyses the market on the basis of the distribution channel and presents an in-depth analysis of:

  • Hospital Pharmacies

  • Retail Pharmacies

  • Online Pharmacies

Next up, the report analyses the market on the basis of regions:

  • North America

    • U.S.

    • Canada

  • Latin America

    • Brazil

    • Mexico

    • Rest of Latin America

  • Western Europe

    • UK

    • France

    • Germany

    • Italy

    • Spain

    • BENELUX countries

    • Nordic Countries

    • Rest of Western Europe

  • Eastern Europe

    • Russia

    • Poland

    • Rest of Eastern Europe

  • Asia Pacific

    • India

    • Australia & New Zealand

    • Rest of APECJ

  • China

  • Japan

  • Middle East & Africa (MEA)

    • GCC Countries

    • South Africa

    • Rest of MEA

In addition, FMI has also considered Year-on-Year (Y-o-Y) growth to understand the predictability of the market and identify growth opportunities for companies operating in the global pulmonary arterial hypertension treatment market.

In the final section of the report, a ‘competitive landscape’ has been included to provide a dashboard view of key companies operating in the global pulmonary arterial hypertension treatment market. The companies analysed are GlaxoSmithKline plc, Eli Lilly and Company, Pfizer Inc., Actelion Inc., (Johnson & Johnson Services, Inc.), United Therapeutic Corporation, SteadyMed Ltd., Gilead Sciences, Inc., Teva Pharmaceuticals Inc., and Bayer AG to name a few. This section is primarily designed to provide a detailed comparative assessment of key providers specific to a market segment in the pulmonary arterial hypertension treatment market and the potential players. This section also includes long- and short-term market strategies and SWOT analysis of the main players operational in the global pulmonary arterial hypertension treatment market.

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Harish Tiwari

Harish Tiwari

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