Chronic Refractory Cough treatment market Snapshot (2023 to 2033)

The global chronic refractory cough treatment market is expected to reach a valuation of US$ 9.2 billion in 2023 and is projected to reach USD 17.1 billion by 2033, trailing a CAGR of 6.39%.

The growing prevalence of refractory chronic cough globally drives the refractory chronic cough therapeutics market. Increased global healthcare spending and disease awareness would increase the market's size, allowing pharmaceutical companies to expand their market share. The medicines in development are centered on cutting-edge methods to treat or ameliorate the illness state.

Report Attribute Details
Expected Market Value (2023) US$ 9.2 billion
Anticipated Forecast Value (2033) US$ 17.1 billion
Projected Growth Rate (2023 to 2033) CAGR 6.39%

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2018 to 2022 Chronic Refractory Cough Management Demand Analysis vs. Forecast 2023 to 2033

The chronic refractory cough treatment market was worth US$ 7 billion in 2018 while growing at a CAGR of 5.62%. In order to relieve patients from cough hypersensitivity, healthcare companies are investing in opiates and GABA (gamma-aminobutyric acid)-related compounds. Opiates serve as effective cough suppressants and possess efficacious antitussive properties to treat chronic intractable cough. Likewise, companies are increasing their production capabilities of tramadol, an opioid medication that is similar to the molecular formula of codeine drugs.

Since chronic cough causes increased body pain, companies in the Chronic refractory cough treatment market are increasing the availability of gabapentin and pregabalin, which are GABA-related compounds, and act as neuromodulators for the treatment of neuropathic pain and epilepsy. It has been found in placebo-controlled trials that; gabapentin is well-tolerated for the treatment of refractory chronic cough. Thus, leading to market expansion.

Considering these factors, the market for Chronic refractory cough treatment is projected to reach US$ 17.1 billion by end of the forecast period, while exhibiting a CAGR of 6.39%.

Which are Some Prominent Drivers of the Chronic Refractory Cough Treatment Market?

Launch of pipeline therapies augmenting the market expansion

The launch of pipeline therapies in late and mid-stage developments, including Orvepitant Maleate, BLU-5937, Gefapixant, BAY1817080, and S-600918, is anticipated to expand the growth quadrant of the Chronic Refractory Cough market size in the coming years. Gefapixant (Merck) is currently in the Phase III stage of development, followed by Orvepitant Maleate (Nerre Therapeutics) which will support market growth.

Also, the use of various off-label therapies and over-the-counter drugs like Neuro-modulating agents (Opioids, Baclofen, Gabapentin, Pregabalin, and Amitriptyline), Proton Pump inhibitors, Inhaled corticosteroids (ICS), and others along with non-pharmacological treatments like speech therapy will fuel product demand. Orvepitant Maleate has demonstrated no safety concerns in the treated population with excellent tolerability. If approved, the drug has the potential to capture a major market share. Thus, leading to market expansion.

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What are the Challenges Projected to be Faced by the Market?

Lack of approved therapies to restrain the growth

A severe dearth of approved therapies in the chronic refractory cough treatment market may restrain its success trajectory. There is a lack of availability of specific biomarkers that can help in the accurate and timely diagnosis of Chronic Refractory Cough. These factors will hamper market expansion.

Region-Wise Insights

What is the growth outlook in North America?

North America leading the market with a significant market share

The North American chronic refractory cough treatment market is projected to reach US$ 6.84 billion by 2033 from US$ 3.9 billion in 2023. It is estimated to grow with a CAGR of 5.77% during the forecast period. This region is expected to dominate the market with a 40% market share, owing to the presence of major market players.

The USA leads the market in this region with approximately 71% market share. Several collaborative efforts were undertaken by major companies to enhance their Research and Development capabilities and ensure high medical standards are expected to impel the demand across this region. Moreover, the majority share can also be attributed to the high disease burden in this region. Rising cases of cough and the rising pediatric population are the key factors that are fuelling the market in this region.

What are the growth prospects in South Asia?

South Asian market to witness the fastest growth

South Asia region is expected to witness the fastest growth of 6.2% over the forecast period. The market in this region is estimated to be worth US$ 4.78 billion, accounting for 28% market share by end of the forecast period.

Strategic partnerships between pharmaceutical companies and government organizations are on a rise in the region, particularly to develop generic drugs and spread awareness amongst healthcare professionals. Growing awareness levels and the rising focus of healthcare providers on the eradication of coughing ailments are expected to boost growth within this region.

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Category wise Insights

By Distribution Channel, which segment will possess the Highest Share?

Retail Pharmacies are dominating the market and driving growth

The retail pharmacy segment is expected to dominate the market with a 55% market share. Growth is attributable to the easy availability and accessibility of these pharmacies. For instance, MedPlus has around 1650 outlets out of which 1,350 are self-owned and the rest are taken as a franchisee. Retailers provide discounts on bulk purchases, offer quick delivery, and always have sufficient product stock, owing to which consumers opt for these distribution channels, thus, driving the segment’s growth.

By Distribution Channel, which segment will experience the Fastest Expansion?

Online Pharmacies to experience Maximum Sales of Chronic Refractory Cough Treatment Drugs

Online pharmacies are estimated to be the fastest-growing segment with a CAGR of 8% during the forecast period. The convenience of delivering medicines to the doorstep is the major advantage of online pharmacies.

The discounted price that online pharmacies offer is also a factor that drives the growth of the Chronic refractory cough treatment market. As per an estimate, there are between 30,000 and 50,000 online pharmacies operating in the United States alone, making online pharmacies a leading segment in this region.

By Drug Class, which segment exhibits significant market share?

Antibiotics to take the lead and drive market growth

This segment is projected to achieve a 45.7% market share by end of the forecast period. The growing usage of antibiotic drugs for the treatment of chronic refractory cough and ongoing research on the development of effective antibiotic therapies are leading to the growth of the antibiotic drug class segment in the global chronic refractory cough treatment market.

Start-ups in Chronic Refractory Cough Treatment Market

  • Founded in 2009, Afferent Pharmaceutical is a US-based, clinical-stage biopharmaceutical company that develops small molecule compounds that target P2X3 receptors for the treatment of chronic pain, respiratory, and urological conditions. Its products include AF-219 which is used for patients with osteoarthritis pain, treatment-refractory chronic cough, and interstitial cystitis/bladder pain syndrome; and AF-220, a second-generation P2X3 antagonist. It received funding of USD 88.1 million from Fidelity Investments, Jennison Associates, and 4 more
  • Founded in 2017, Nocion Therapeutics is a Waltham, US-based start-up that is involved in developing therapies for treating cough, itch, pain, and inflammation diseases. It has developed a proprietary platform through which they are developing small molecules called notions, which target activated sensory neurons. It enters inflamed nociceptors through large-pore channels. It received funding of USD 42 million from Canaan Partners, F-Prime Capital, and 2 others.

Market Competition

The market is fragmented and moderately competitive. The strategies like mergers and acquisitions adopted by major market players will boost the market growth. The major players in the market are: Bayer AG, Sun Pharmaceutical Industries Ltd, Aurobindo Pharma Ltd, Mylan N.V., GlaxoSmithKline, Hikma Pharmaceuticals Plc, AstraZeneca, Bausch Health, Novartis AG, Cipla Inc, Glenmark Pharmaceuticals Ltd., Teva Pharmaceutical Industries Ltd, Alitair Pharmaceuticals, NeRRe Therapeutics, Amneal Pharmaceuticals, Inc

Some recent developments in this industry are:

  • On September 6, 2021, Bayer AG announced the results from PAGANINI, the Phase IIb dose-finding study evaluating the efficacy and safety of its investigational orally administered, potent, and selective P2X3 receptor antagonist eliapixant (BAY1817080) in patients with refractory chronic cough (RCC).
  • The primary efficacy outcome was met showing a statistically significant reduction in the 24-hour cough count (average hourly cough frequency based on 24-hour sound recordings) of up to 27% for eliapixant 75 mg twice daily over placebo after 12 weeks of treatment.

Report Scope

Report Attribute Details
Market Value in 2023 US$ 9.2 billion
Market Value in 2033 US$ 17.1 billion
Growth Rate CAGR of 6.39% from 2023 to 2033
Base Year for Estimation 2022
Historical Data 2018 to 2022
Forecast Period 2023 to 2033
Quantitative Units Revenue in USD billion and CAGR from 2023 to 2033
Report Coverage Revenue Forecast, Volume Forecast, Company Ranking, Competitive Landscape, Growth Factors, Trends, and Pricing Analysis
Segments Covered
  • Drug Class
  • Route of Administration
  • Distribution Channel
  • Region
Regions Covered
  • North America
  • Latin America
  • Europe
  • South Asia
  • East Asia
  • Oceania
  • Middle East & Africa (MEA)
Key Countries Profiled
  • USA
  • Canada
  • Brazil
  • Mexico
  • Germany
  • UK
  • France
  • Spain
  • Italy
  • India
  • China
  • Japan
  • Malaysia
  • Singapore
  • Thailand
  • South Korea
  • Australia
  • New Zealand
  • GCC Countries
  • South Africa
  • Israel
Key Companies Profiled
  • Bayer AG
  • Sun Pharmaceutical Industries Ltd
  • Aurobindo Pharma Ltd
  • Mylan N.V.
  • GSK Plc.
  • Hikma Pharmaceuticals Plc
  • AstraZeneca Plc.
  • Bausch Health
  • Novartis AG
  • Cipla Inc.
  • Glenmark Pharmaceuticals Ltd.
  • Teva Pharmaceutical Industries Ltd
  • Alitair Pharmaceuticals
  • NeRRe Therapeutics
  • Amneal Pharmaceuticals Inc.
Customization Available Upon Request

Key Segments Profiled in the Chronic Refractory Cough Treatment Industry Survey

By Drug Class:

  • Antibiotics
  • Decongestants
  • Corticosteroids
  • Antihistamines
  • Acid Blockers
  • Others

By Route of administration:

  • Oral
  • Nasal
  • Parenteral
  • Others

By Distribution Channel:

  • Hospital Pharmacies
  • Retail Pharmacies
  • Online Pharmacies

By Region:

  • North America
  • Latin America
  • Europe
  • South Asia
  • East Asia
  • Oceania
  • Middle East & Africa

Frequently Asked Questions

What is the anticipated growth of the chronic refractory cough treatment market until 2033?

FMI projects the global Chronic Refractory Cough treatment market to expand at a 6.39 % value CAGR by 2033.

What is the estimated market value of the chronic refractory cough treatment market expected in 2033?

The global chronic refractory cough treatment market is expected to garner a market value of US$ 17.1 billion by 2033.

Which region is forecast to be the most lucrative for chronic refractory cough treatment market growth?

FMI has projected North America to be one of the most profitable regions for the chronic refractory cough treatment market.

Which region is expected to grow fastest during the forecast period?

South Asia region is expected to grow fastest during the forecast period, expanding at a 6.2% CAGR

What is the Market Value in 2023?

The market in 2023 is valued at US$ 9.2 billion.

What is the Growth Outlook for the Market?

The market is anticipated to experience a 6.39% CAGR from 2023 to 2033.

How did the Market Perform Historically?

From 2018 to 2022, the market expanded at a 5.62% CAGR.

What is the Estimated Market Value for 2033?

By 2033, the market is estimated to reach US$ 17.1 billion.

What is South Asia’s Market CAGR over the Forecast period?

South Asia is likely to expand at a CAGR of 6.2% over the forecast period. 

Table of Content
1. Executive Summary | Chronic Refractory Cough Treatment Market
        1.1. Global Market Outlook
        1.2. Demand-side Trends
        1.3. Supply-side Trends
        1.4. Technology Roadmap Analysis
        1.5. Analysis and Recommendations
2. Market Overview
        2.1. Market Coverage / Taxonomy
        2.2. Market Definition / Scope / Limitations
3. Market Background
        3.1. Market Dynamics
            3.1.1. Drivers
            3.1.2. Restraints
            3.1.3. Opportunity
            3.1.4. Trends
        3.2. Scenario Forecast
            3.2.1. Demand in Optimistic Scenario
            3.2.2. Demand in Likely Scenario
            3.2.3. Demand in Conservative Scenario
        3.3. Opportunity Map Analysis
        3.4. Investment Feasibility Matrix
        3.5. PESTLE and Porter’s Analysis
        3.6. Regulatory Landscape
            3.6.1. By Key Regions
            3.6.2. By Key Countries
        3.7. Regional Parent Market Outlook
4. Global Market Analysis 2018 to 2022 and Forecast, 2023 to 2033
        4.1. Historical Market Size Value (US$ Million) Analysis, 2018 to 2022
        4.2. Current and Future Market Size Value (US$ Million) Projections, 2023 to 2033
            4.2.1. Y-o-Y Growth Trend Analysis
            4.2.2. Absolute $ Opportunity Analysis
5. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Drug Class
        5.1. Introduction / Key Findings
        5.2. Historical Market Size Value (US$ Million) Analysis By Drug Class, 2018 to 2022
        5.3. Current and Future Market Size Value (US$ Million) Analysis and Forecast By Drug Class, 2023 to 2033
            5.3.1. Antibiotics
            5.3.2. Decongestants
            5.3.3. Corticosteroids
            5.3.4. Antihistamines
            5.3.5. Acid Blockers
            5.3.6. Others
        5.4. Y-o-Y Growth Trend Analysis By Drug Class, 2018 to 2022
        5.5. Absolute $ Opportunity Analysis By Drug Class, 2023 to 2033
6. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Route of Administration
        6.1. Introduction / Key Findings
        6.2. Historical Market Size Value (US$ Million) Analysis By Route of Administration, 2018 to 2022
        6.3. Current and Future Market Size Value (US$ Million) Analysis and Forecast By Route of Administration, 2023 to 2033
            6.3.1. Oral
            6.3.2. Nasal
            6.3.3. Parenteral
            6.3.4. Others
        6.4. Y-o-Y Growth Trend Analysis By Route of Administration, 2018 to 2022
        6.5. Absolute $ Opportunity Analysis By Route of Administration, 2023 to 2033
7. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Distribution Channel 
        7.1. Introduction / Key Findings
        7.2. Historical Market Size Value (US$ Million) Analysis By Distribution Channel, 2018 to 2022
        7.3. Current and Future Market Size Value (US$ Million) Analysis and Forecast By Distribution Channel, 2023 to 2033
            7.3.1. Hospital Pharmacies
            7.3.2. Retail Pharmacies
            7.3.3. Online Pharmacies
        7.4. Y-o-Y Growth Trend Analysis By Distribution Channel, 2018 to 2022
        7.5. Absolute $ Opportunity Analysis By Distribution Channel, 2023 to 2033
8. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Region
        8.1. Introduction
        8.2. Historical Market Size Value (US$ Million) Analysis By Region, 2018 to 2022
        8.3. Current Market Size Value (US$ Million) Analysis and Forecast By Region, 2023 to 2033
            8.3.1. North America
            8.3.2. Latin America
            8.3.3. Europe
            8.3.4. South Asia
            8.3.5. East Asia
            8.3.6. Oceania
            8.3.7. Middle East & Africa (MEA)
        8.4. Market Attractiveness Analysis By Region
9. North America Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
        9.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022
        9.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033
            9.2.1. By Country
                9.2.1.1. USA
                9.2.1.2. Canada
            9.2.2. By Drug Class
            9.2.3. By Route of Administration
            9.2.4. By Distribution Channel
        9.3. Market Attractiveness Analysis
            9.3.1. By Country
            9.3.2. By Drug Class
            9.3.3. By Route of Administration
            9.3.4. By Distribution Channel
        9.4. Key Takeaways
10. Latin America Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
        10.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022
        10.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033
            10.2.1. By Country
                10.2.1.1. Brazil
                10.2.1.2. Mexico
                10.2.1.3. Rest of Latin America
            10.2.2. By Drug Class
            10.2.3. By Route of Administration
            10.2.4. By Distribution Channel
        10.3. Market Attractiveness Analysis
            10.3.1. By Country
            10.3.2. By Drug Class
            10.3.3. By Route of Administration
            10.3.4. By Distribution Channel
        10.4. Key Takeaways
11. Europe Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
        11.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022
        11.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033
            11.2.1. By Country
                11.2.1.1. Germany
                11.2.1.2. UK
                11.2.1.3. France
                11.2.1.4. Spain
                11.2.1.5. Italy
                11.2.1.6. Rest of Europe
            11.2.2. By Drug Class
            11.2.3. By Route of Administration
            11.2.4. By Distribution Channel
        11.3. Market Attractiveness Analysis
            11.3.1. By Country
            11.3.2. By Drug Class
            11.3.3. By Route of Administration
            11.3.4. By Distribution Channel
        11.4. Key Takeaways
12. South Asia Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
        12.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022
        12.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033
            12.2.1. By Country
                12.2.1.1. India
                12.2.1.2. Malaysia
                12.2.1.3. Singapore
                12.2.1.4. Thailand
                12.2.1.5. Rest of South Asia
            12.2.2. By Drug Class
            12.2.3. By Route of Administration
            12.2.4. By Distribution Channel
        12.3. Market Attractiveness Analysis
            12.3.1. By Country
            12.3.2. By Drug Class
            12.3.3. By Route of Administration
            12.3.4. By Distribution Channel
        12.4. Key Takeaways
13. East Asia Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
        13.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022
        13.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033
            13.2.1. By Country
                13.2.1.1. China
                13.2.1.2. Japan
                13.2.1.3. South Korea
            13.2.2. By Drug Class
            13.2.3. By Route of Administration
            13.2.4. By Distribution Channel
        13.3. Market Attractiveness Analysis
            13.3.1. By Country
            13.3.2. By Drug Class
            13.3.3. By Route of Administration
            13.3.4. By Distribution Channel
        13.4. Key Takeaways
14. Oceania Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
        14.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022
        14.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033
            14.2.1. By Country
                14.2.1.1. Australia
                14.2.1.2. New Zealand
            14.2.2. By Drug Class
            14.2.3. By Route of Administration
            14.2.4. By Distribution Channel
        14.3. Market Attractiveness Analysis
            14.3.1. By Country
            14.3.2. By Drug Class
            14.3.3. By Route of Administration
            14.3.4. By Distribution Channel
        14.4. Key Takeaways
15. MEA Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
        15.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022
        15.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033
            15.2.1. By Country
                15.2.1.1. GCC Countries
                15.2.1.2. South Africa
                15.2.1.3. Israel
                15.2.1.4. Rest of MEA
            15.2.2. By Drug Class
            15.2.3. By Route of Administration
            15.2.4. By Distribution Channel
        15.3. Market Attractiveness Analysis
            15.3.1. By Country
            15.3.2. By Drug Class
            15.3.3. By Route of Administration
            15.3.4. By Distribution Channel
        15.4. Key Takeaways
16. Key Countries Market Analysis
        16.1. US
            16.1.1. Pricing Analysis
            16.1.2. Market Share Analysis, 2022
                16.1.2.1. By Drug Class
                16.1.2.2. By Route of Administration
                16.1.2.3. By Distribution Channel
        16.2. Canada
            16.2.1. Pricing Analysis
            16.2.2. Market Share Analysis, 2022
                16.2.2.1. By Drug Class
                16.2.2.2. By Route of Administration
                16.2.2.3. By Distribution Channel
        16.3. Brazil
            16.3.1. Pricing Analysis
            16.3.2. Market Share Analysis, 2022
                16.3.2.1. By Drug Class
                16.3.2.2. By Route of Administration
                16.3.2.3. By Distribution Channel
        16.4. Mexico
            16.4.1. Pricing Analysis
            16.4.2. Market Share Analysis, 2022
                16.4.2.1. By Drug Class
                16.4.2.2. By Route of Administration
                16.4.2.3. By Distribution Channel
        16.5. Germany
            16.5.1. Pricing Analysis
            16.5.2. Market Share Analysis, 2022
                16.5.2.1. By Drug Class
                16.5.2.2. By Route of Administration
                16.5.2.3. By Distribution Channel
        16.6. UK
            16.6.1. Pricing Analysis
            16.6.2. Market Share Analysis, 2022
                16.6.2.1. By Drug Class
                16.6.2.2. By Route of Administration
                16.6.2.3. By Distribution Channel
        16.7. France
            16.7.1. Pricing Analysis
            16.7.2. Market Share Analysis, 2022
                16.7.2.1. By Drug Class
                16.7.2.2. By Route of Administration
                16.7.2.3. By Distribution Channel
        16.8. Spain
            16.8.1. Pricing Analysis
            16.8.2. Market Share Analysis, 2022
                16.8.2.1. By Drug Class
                16.8.2.2. By Route of Administration
                16.8.2.3. By Distribution Channel
        16.9. Italy
            16.9.1. Pricing Analysis
            16.9.2. Market Share Analysis, 2022
                16.9.2.1. By Drug Class
                16.9.2.2. By Route of Administration
                16.9.2.3. By Distribution Channel
        16.10. India
            16.10.1. Pricing Analysis
            16.10.2. Market Share Analysis, 2022
                16.10.2.1. By Drug Class
                16.10.2.2. By Route of Administration
                16.10.2.3. By Distribution Channel
        16.11. Malaysia
            16.11.1. Pricing Analysis
            16.11.2. Market Share Analysis, 2022
                16.11.2.1. By Drug Class
                16.11.2.2. By Route of Administration
                16.11.2.3. By Distribution Channel
        16.12. Singapore
            16.12.1. Pricing Analysis
            16.12.2. Market Share Analysis, 2022
                16.12.2.1. By Drug Class
                16.12.2.2. By Route of Administration
                16.12.2.3. By Distribution Channel
        16.13. Thailand
            16.13.1. Pricing Analysis
            16.13.2. Market Share Analysis, 2022
                16.13.2.1. By Drug Class
                16.13.2.2. By Route of Administration
                16.13.2.3. By Distribution Channel
        16.14. China
            16.14.1. Pricing Analysis
            16.14.2. Market Share Analysis, 2022
                16.14.2.1. By Drug Class
                16.14.2.2. By Route of Administration
                16.14.2.3. By Distribution Channel
        16.15. Japan
            16.15.1. Pricing Analysis
            16.15.2. Market Share Analysis, 2022
                16.15.2.1. By Drug Class
                16.15.2.2. By Route of Administration
                16.15.2.3. By Distribution Channel
        16.16. South Korea
            16.16.1. Pricing Analysis
            16.16.2. Market Share Analysis, 2022
                16.16.2.1. By Drug Class
                16.16.2.2. By Route of Administration
                16.16.2.3. By Distribution Channel
        16.17. Australia
            16.17.1. Pricing Analysis
            16.17.2. Market Share Analysis, 2022
                16.17.2.1. By Drug Class
                16.17.2.2. By Route of Administration
                16.17.2.3. By Distribution Channel
        16.18. New Zealand
            16.18.1. Pricing Analysis
            16.18.2. Market Share Analysis, 2022
                16.18.2.1. By Drug Class
                16.18.2.2. By Route of Administration
                16.18.2.3. By Distribution Channel
        16.19. GCC Countries
            16.19.1. Pricing Analysis
            16.19.2. Market Share Analysis, 2022
                16.19.2.1. By Drug Class
                16.19.2.2. By Route of Administration
                16.19.2.3. By Distribution Channel
        16.20. South Africa
            16.20.1. Pricing Analysis
            16.20.2. Market Share Analysis, 2022
                16.20.2.1. By Drug Class
                16.20.2.2. By Route of Administration
                16.20.2.3. By Distribution Channel
        16.21. Israel
            16.21.1. Pricing Analysis
            16.21.2. Market Share Analysis, 2022
                16.21.2.1. By Drug Class
                16.21.2.2. By Route of Administration
                16.21.2.3. By Distribution Channel
17. Market Structure Analysis
        17.1. Competition Dashboard
        17.2. Competition Benchmarking
        17.3. Market Share Analysis of Top Players
            17.3.1. By Regional
            17.3.2. By Drug Class
            17.3.3. By Route of Administration
            17.3.4. By Distribution Channel
18. Competition Analysis
        18.1. Competition Deep Dive
            18.1.1. Bayer AG
                18.1.1.1. Overview
                18.1.1.2. Product Portfolio
                18.1.1.3. Profitability by Market Segments
                18.1.1.4. Sales Footprint
                18.1.1.5. Strategy Overview
                    18.1.1.5.1. Marketing Strategy
            18.1.2. Sun Pharmaceutical Industries Ltd
                18.1.2.1. Overview
                18.1.2.2. Product Portfolio
                18.1.2.3. Profitability by Market Segments
                18.1.2.4. Sales Footprint
                18.1.2.5. Strategy Overview
                    18.1.2.5.1. Marketing Strategy
            18.1.3. Aurobindo Pharma Ltd
                18.1.3.1. Overview
                18.1.3.2. Product Portfolio
                18.1.3.3. Profitability by Market Segments
                18.1.3.4. Sales Footprint
                18.1.3.5. Strategy Overview
                    18.1.3.5.1. Marketing Strategy
            18.1.4. Mylan N.V.
                18.1.4.1. Overview
                18.1.4.2. Product Portfolio
                18.1.4.3. Profitability by Market Segments
                18.1.4.4. Sales Footprint
                18.1.4.5. Strategy Overview
                    18.1.4.5.1. Marketing Strategy
            18.1.5. GlaxoSmithKline
                18.1.5.1. Overview
                18.1.5.2. Product Portfolio
                18.1.5.3. Profitability by Market Segments
                18.1.5.4. Sales Footprint
                18.1.5.5. Strategy Overview
                    18.1.5.5.1. Marketing Strategy
            18.1.6. Hikma Pharmaceuticals Plc
                18.1.6.1. Overview
                18.1.6.2. Product Portfolio
                18.1.6.3. Profitability by Market Segments
                18.1.6.4. Sales Footprint
                18.1.6.5. Strategy Overview
                    18.1.6.5.1. Marketing Strategy
            18.1.7. AstraZeneca
                18.1.7.1. Overview
                18.1.7.2. Product Portfolio
                18.1.7.3. Profitability by Market Segments
                18.1.7.4. Sales Footprint
                18.1.7.5. Strategy Overview
                    18.1.7.5.1. Marketing Strategy
            18.1.8. Bausch Health
                18.1.8.1. Overview
                18.1.8.2. Product Portfolio
                18.1.8.3. Profitability by Market Segments
                18.1.8.4. Sales Footprint
                18.1.8.5. Strategy Overview
                    18.1.8.5.1. Marketing Strategy
            18.1.9. Novartis AG
                18.1.9.1. Overview
                18.1.9.2. Product Portfolio
                18.1.9.3. Profitability by Market Segments
                18.1.9.4. Sales Footprint
                18.1.9.5. Strategy Overview
                    18.1.9.5.1. Marketing Strategy
            18.1.10. Cipla Inc.
                18.1.10.1. Overview
                18.1.10.2. Product Portfolio
                18.1.10.3. Profitability by Market Segments
                18.1.10.4. Sales Footprint
                18.1.10.5. Strategy Overview
                    18.1.10.5.1. Marketing Strategy
            18.1.11. Glenmark Pharmaceuticals Ltd.
                18.1.11.1. Overview
                18.1.11.2. Product Portfolio
                18.1.11.3. Profitability by Market Segments
                18.1.11.4. Sales Footprint
                18.1.11.5. Strategy Overview
                    18.1.11.5.1. Marketing Strategy
            18.1.12. Teva Pharmaceutical Industries Ltd
                18.1.12.1. Overview
                18.1.12.2. Product Portfolio
                18.1.12.3. Profitability by Market Segments
                18.1.12.4. Sales Footprint
                18.1.12.5. Strategy Overview
                    18.1.12.5.1. Marketing Strategy
            18.1.13. Alitair Pharmaceuticals
                18.1.13.1. Overview
                18.1.13.2. Product Portfolio
                18.1.13.3. Profitability by Market Segments
                18.1.13.4. Sales Footprint
                18.1.13.5. Strategy Overview
                    18.1.13.5.1. Marketing Strategy
            18.1.14. NeRRe Therapeutics
                18.1.14.1. Overview
                18.1.14.2. Product Portfolio
                18.1.14.3. Profitability by Market Segments
                18.1.14.4. Sales Footprint
                18.1.14.5. Strategy Overview
                    18.1.14.5.1. Marketing Strategy
            18.1.15. AMillioneal Pharmaceuticals, Inc.
                18.1.15.1. Overview
                18.1.15.2. Product Portfolio
                18.1.15.3. Profitability by Market Segments
                18.1.15.4. Sales Footprint
                18.1.15.5. Strategy Overview
                    18.1.15.5.1. Marketing Strategy
19. Assumptions & Acronyms Used
20. Research Methodology
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