Vascular Endothelial Growth Factor Inhibitor Market

Vascular Endothelial Growth Factor Inhibitor Market: Global Industry Analysis and Opportunity Assessment 2017-2027

  • Ongoing
  • August 2020
  • REP-GB-3292
Vascular Endothelial Growth Factor Inhibitor Market

  • US$5,000
  • US$7,500
  • US$10,000

This Vascular Endothelial Growth Factor Inhibitor market study offers a comprehensive analysis of the business models, key strategies, and respective market shares of some of the most prominent players in this landscape. Along with an in-depth commentary on the key influencing factors, market statistics in terms of revenues, segment-wise data, region-wise data, and country-wise data are offered in the full study. This study is one of the most comprehensive documentation that captures all the facets of the evolving Vascular Endothelial Growth Factor Inhibitor market.

Vascular Endothelial Growth Factor (VEGF), is a process of formation of new blood vessels from endothelial cells or the pre-existing vessels. VEGF’s normal function is during embryonic development, the formation of new blood vessels after injury, in muscle after exercise and as a bypass for a blocked vessel. Overexpression of VEGF can be fatal as they can grow into cancerous cells. VEGF plays both beneficial and damaging roles in organisms. VEGF takes circulating endothelial precursor cells and acts as a growth medium for immature tumor cells. The affinity of VEGF toward endothelial cells is mediated through VEGF-specific tyrosine-kinase receptor: VEGFR-1, VEGFR-2, and VEGFR-3.  Hence VEGF and its receptors play a major role in the growth of tumor cells. The endotheliotropic property of VEGF causes a major concern for developing Vascular Endothelial Growth Factor Receptor Inhibitor. The VEGF family in mammals comprises of members VEGF-A, VEGF-B, VEGF-C, VEGF-D, and PIGF, out of these the VEGF-A is responsible for angiogenesis and migration and mitosis of endothelial cells. Many therapeutic strategies are developed for inhibiting the signal transduction of VEGF. Some of the therapeutic options are monoclonal antibodies against VEGF or VEGFR, soluble VEGF and VEGFR hybrids and tyrosine kinase inhibitors.

Vascular Endothelial Growth Factor Inhibitor Market: Drivers and Restraints

Market Growth Analysis

Disclaimer: This data is only a representation. Actual data may vary and will be available in the report.

COVID -19 : Impact Analysis

Request the coronavirus impact analysis across industries and markets

Request Covid -19 Impact
The global increase in the prevalence of cancer and recognition of therapeutic opportunities offered by oncology treatments have boosted pharmaceutical industry to develop new agents to treat cancer. According to WHO, the new cancer cases are expected to rise by 70% in coming two decades.  Approximately 60% of malignant tumors express high concentrations of VEGF, therapeutic option to inhibit the VEGF tumor causing pathway has become a major concern for all researchers.

Some of the restraining factors for VEGF inhibitor to be a silver bullet in the treatment of cancer is that angiogenesis is not the only factor causing a tumor. While the lesser known restraints are the side effects caused by VEGF inhibitors are bleeding and increased blood pressure

Vascular Endothelial Growth Factor Inhibitor Market: Segmentation

The Vascular Endothelial Growth Factor market is segmented according to the mode of action of the drug, route of administration, end users, and geography. The segmentation by mode of action of the drug is tyrosine kinase inhibitor: inhibits the adenosine triphosphate binding site, monoclonal antibody: they bind to VEGF-A preventing it from binding to receptors and activating the signaling cascades that lead to angiogenesis and vascular endothelial growth factor receptor hybrids: act as a decoy receptor and prevents binding of the ligand to its natural receptors. By route of administration, it is segmented as oral and intravenous. By end user, the segmentation is classified as hospitals, ambulatory surgical centers, and cancer research institutes. Segmentation by Geography is North America, West Europe, APEJ, Japan, Eastern Europe, Latin America and the Middle East and Africa.

Vascular Endothelial Growth Factor Inhibitor Market: Overview

Vascular Endothelial Growth Factor Inhibitors are also termed as Angiogenesis Inhibitor which inhibits the growth of the new blood vessels. Angiogenesis Inhibitors are effective in the treatment of cancer macular degeneration in the eye and diseases that involve proliferation of blood vessels. VEGF or angiogenesis is regulated by the activity of endogenous stimulators and inhibitors. Endogenous inhibitors are present in the body involved in regulating the process of blood vessel formation. Endogenous inhibitors are derived from the cellular matrix and basement protein. Among the factors responsible for angiogenesis, VEGF is the most potent and has high expression in ovarian, endometrial and cervical cancer. Inhibition of angiogenesis by VEGF requires anti – VEGF / anti – angiogenesis factors which reduce the production of pro – angiogenic factor thereby preventing them from binding to their receptors. The commonly used therapy for VEGF pathway inhibition is a monoclonal antibody against VEGF or VEGFR, soluble VEGFR hybrids, and tyrosine kinase inhibitors. Among this, the most widely used treatment is with monoclonal antibody Bevacizumab.

Vascular Endothelial Growth Factor Inhibitor Market: Regional Overview

The monoclonal antibody segment is growing faster in North America and Europe vascular endothelial growth factor inhibitor marketvascular endothelial growth factor inhibitor market. North America region accounts for the largest market share for tyrosine kinase inhibitor followed by Asia-Pacific and Europe. China will drive the Asia Pacific market by providing growth opportunities from upcoming companies. In the Asia-Pacific market, the countries like China, India and South Asian countries will dominate the market. According to WHO the emerging market for cancer is Africa, Asia, and the US.

Vascular Endothelial Growth Factor Inhibitor Market: Key Players

Some of the  players in the market of Vascular Endothelial Growth Factor Inhibitor are Pfizer Inc., Novartis Pharmaceutical Corporation, AstraZeneca, Bayer Healthcare, Merck & Co. Inc., Genetech Inc., Eli Lilly, Sanofi Aventis, GlaxoSmithKline, Bristol-Myer Squibb and Boehringer Ingelheim

The report is a compilation of first-hand information, qualitative and quantitative assessment by industry analysts, inputs from industry experts and industry participants across the value chain. The report provides in-depth analysis of parent market trends, macro-economic indicators and governing factors along with market attractiveness as per segments. The report also maps the qualitative impact of various market factors on market segments and geographies.

NOTE - All statements of fact, opinion, or analysis expressed in reports are those of the respective analysts. They do not necessarily reflect formal positions or views of Future Market Insights.

Unique Requirements? Customize this Report

  • Customize by Region, Country, Application, Product, & other segments
  • Integrate our Insights with your Existing Data
  • Determine the scope of the study to suit your requirements

Let FMI Help You!

  • Gain Insights on Key Vascular Endothelial Growth Factor Inhibitor Market Impacting Forces
  • Know the Winning Strategies of Market Leaders
  • Get Deep-Dive Analysis on Each Segment
  • Identify the Sources that will Drive Top-Line Revenue

The report covers exhaustive analysis on:

  • Market Segments
  • Market Dynamics
  • Market Size
  • Supply & Demand
  • Current Trends/Issues/Challenges
  • Competition & Companies involved
  • Technology
  • Value Chain

Regional analysis includes

  • North America (U.S., Canada)
  • Latin America (Mexico, Brazil)
  • Western Europe (Germany, Italy, U.K, Spain, France, Nordic countries, BENELUX)
  • Eastern Europe (Russia, Poland, Rest Of Eastern Europe)
  • Asia Pacific Excluding Japan (China, India, ASEAN, Australia & New Zealand)
  • Japan
  • Middle Eastand Africa (GCC, S. Africa, N. Africa, Rest Of MEA)

Report Highlights:

  • Detailed overview of parent market
  • Changing market dynamics in the industry
  • In-depth market segmentation
  • Historical, current and projected market size in terms of volume and value
  • Recent industry trends and developments
  • Competitive landscape
  • Strategies of key players and products offered
  • Potential and niche segments, geographical regions exhibiting promising growth
  • A neutral perspective on market performance
  • Must-have information for market players to sustain and enhance their market footprint.
Frequently Asked Questions

Why choose FMI?
  • With a global presence and a trusted partner to several Fortune 500 firms, FMI covers 1 billion+ data points to build a diversified portfolio for market benchmarking
  • Market Reports researched and peer reviewed by industry experts from across the globe
  • We follow a multi-dimensional method of analysis monitoring a three-layer data validation process
  • In addition to demand-side market assessment, our data triangulation methodology involves supply-side research
  • Primary research includes mandatory field interviews with stakeholders involved
  • Customizing reports according to client specification is also our forte
  • The current and future market size, covering each aspect and nuanced trends across key national and geographic markets
  • An overview of the market report, providing an imperative visual of the varied market subdivisions and overall forecast statistics in terms of value and volume
  • Extensive database and key dynamics elevating the market with varied verticals associated
  • Underlying Vascular Endothelial Growth Factor Inhibitor Market forces that are compelling consumers or businesses to purchase the product
  • How novel technologies and consumer-centric innovations will create new value-adding opportunities for companies active in the Vascular Endothelial Growth Factor Inhibitor Market
  • What will be environment and regulatory impacts on the market over the next decade
  • Investment Feasibility Matrix - It shows returns on investment, level of competition, success rate of investment, and potential risks associated with the market. The analysis shows that the competition is high in the established market, while the returns for short-term investment are also taken into consideration
  • Relative Maturity Mapping – The relative maturity is measured according to three growth phases (growth, maturity, decline)
  • Relative PLC (Product Life Cycle) – Analysis of the emergence of prominent players and competitive test prices which are driving factors behind every market. (expected market behavior, observed market behavior, expected market performance, observed market performance)
Get in touch
Harish Tiwari

Harish Tiwari

Global Head - Business Development

Akshay Godge

Akshay Godge

Client Partner - Global Business Development

Our Clients

Request Sample Request customization Request Methodology