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Hypoparathyroidism Treatment Market Snapshot (2023 to 2033)

The global hypoparathyroidism treatment market was valued at US$ 777.4 million as of 2022 and is likely to reach US$ 841.9 million in 2023. During the 2023 to 2033 forecast period, the market is expected to incline at a CAGR of 7.7%, and is expected to total US$ 1,767.4 million by the end of the said period of assessment.

Parathyroid hormone (PTH) plays a pivotal role in maintaining the optimum level of calcium, phosphate, and calcitriol (active Vitamin D) in the blood and bones. Hypoparathyroidism is an uncommon endocrine disorder that develops due to low production or absence of parathyroid hormone.

Globally, hypoparathyroidism affects approximately 200, 000 people, out of which most cases are associated with accidental damage or removal of the parathyroid gland during thyroid surgery. Other cases are associated with autoimmune, hereditary, and idiopathic issues. The current standard treatment involves the use of calcium and vitamin D analogues (Vitamin D2 & Vitamin D3).

On the other hand, hormonal therapy is also gaining attention, where the primary treatment has found success in cases of severe hypoparathyroidism. The side effects include potential risks associated with developing osteosarcoma has limited adoption rates. Manufacturers in the market are focusing on investing significantly in the development of safe, and effective hormonal therapies in long-term strategies.

Attributes Details
Hypoparathyroidism Treatment Market Value (2022) US$ 777.4 million
Hypoparathyroidism Treatment Market Value (2023) US$ 841.9 million
Hypoparathyroidism Treatment Market Expected Value (2033) US$ 1,767.4 million
Hypoparathyroidism Treatment Market Projected CAGR (2023 to 2033) 7.7%

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How Does the Future Outlook for Hypoparathyroidism Treatment Market Compare to Historical Data?

Between 2018 and 2022, the demand for calcium supplements for treating hypoparathyroidism dominated the global market mainly owing to cost and efficacy benefits over hormonal therapies and other drugs. Subsequently, rising research and development activities supported market growth.

NATPARA (Takeda), and Rocaltrol (Roche) are some of the commonly prescribed drugs to treat moderate to severe hypoparathyroidism. Issues of product recall and the resultant mismanagement of treatments have led to hospitalizations in severe cases. Manufacturers such as Ascendis Pharma A/S, EnteraBio Ltd, ProLynx, Inc., and Extend Biosciences, Inc. have hormonal therapies in the pipeline which have delivered superior patient outcomes.

The market is expected to witness an increase in patient screening for several thyroid conditions owing to growing patient awareness. The approval and designation of hypothyroidism drugs as orphan products by the United States FDA and the European Commission (EC), coupled with the untapped patient population is expected to have a positive impetus on market growth.

The emergence of personalized medicines, the rapid rise in demand for biologics for hypothyroidism, and consolidation activities by market players will create significant opportunities for the expansion of the hypothyroidism treatment market size over the forecast period, which is projected to expand at a CAGR of 7.7% through 2033.

How are Changes in Reimbursement Policies Fueling Market Growth?

Government Initiatives to Propel Market Growth

Government support in terms of receiving an orphan drug designation from regulatory bodies such as the United States FDA and European Commission (EC) and financial and tax incentive factors are expected to result in a high return on investment for companies developing novel drugs for treating hypoparathyroidism.

The United States FDA’s orphan drug status is given to biologics affecting fewer than 200,000 people in the United States alone with the benefits of various incentives including tax incentives for qualified clinical trials and market exclusiveness on receiving regulatory approval.

For hypoparathyroidism, NATPARA is the only drug issued with a black box warning, which was notified by United States FDA, in January 2015, and currently has exclusivity until 2022. Also, the treatment is covered by several insurance companies and co-pay policies. Such initiatives are expected to boost the production of novel drugs, which is expected to positively influence the growth of the market shortly.

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Why are Labelling Restrictions on NATPARA Limiting Market Growth?

Side Effects Owing to the Usage of NATPARA to Restrict the Market Expansion

Currently, NATPARA is the only available drug to treat hypoparathyroidism. Because of its side effects including a potential risk of osteosarcoma, high blood calcium levels, and reduced sense of touch or pain sensation in joints, which could result in hospitalization. The drug is only made available through NAPTARA Risk Evaluation and Mitigation Strategy (REMS) Programs.

Hence, in most of the cases, oral medications are considered as standard treatment for hypoparathyroidism. This limits the adoption of available hormonal therapy. Further, long-term beneficial drug usage symptoms have still not been demonstrated across clinical trials, which might limit the adoption of therapy in patients given the high price of the injection. Drug literature review 2018 states that therapy with rhPTH (1-84) is a long-term management option, where more long-term efficacy and safety data are needed in humans. EMA’s Committee for Medicinal Products for Human Use (CHMP) has recommended conditional approval for NATPARA instead of these side effects. Thus, labeling restrictions are expected to hold back the penetration of NATPARA in the major global markets, thereby hampering the overall growth of the market.

How are Small Molecule Biologics Creating Growth Opportunities?

The Development of Biologics is Anticipated to Drive Market Growth

The hypoparathyroidism treatment market is shifting towards the demand for biologics over conventional drug alternatives. The efficacy of biologics and their ability to mimic natural body hormones is greater as compared to small molecule options in conventional therapy. This benefit is an essential influencing factor driving the demand for biologics.

Bologics promote the conversion of vitamin D into active forms, which increases the absorption of oral calcium supplements, resulting in synergies with conventional calcium in supplement therapy. Considering the aforementioned factors, the emergence of biologics is expected to offer lucrative opportunities for the growth of the hypothyroidism treatment market.

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Comparative Analysis of the Adjacent Markets

Hypoparathyroidism Treatment Tools Market:

Differentiating Aspects Hypoparathyroidism Treatment Tools Market
CAGR (2023 to 2033) 7.7%
Market Valuation in 2023 US$ 841.9 million
Projected Market Value in 2033 US$ 1,767.4 million
Growth Factors The market is expected to witness an increase in patient screening for several thyroid conditions owing to growing patient awareness.
Opportunities The emergence of personalized medicines, the rapid rise in demand for biologics for hypothyroidism, and consolidation activities by market players will create significant opportunities for the expansion of the hypothyroidism treatment market
Key Trends The emergence of personalized medicines and consolidation activities by market players.

Hypocalcaemia Treatment Market:

Differentiating Aspects Hypocalcaemia Treatment Market
CAGR (2023 to 2033) 5.6%
Market Valuation in 2023 US$ 3.5 billion
Projected Market Value in 2033 US$ 6 billion
Growth Factors The increased prevalence of hypocalcemia, rising knowledge about the advantages of early detection and treatment, and increasing preferences for preventative therapies are driving market expansion.
Opportunities Due to the growing number of clinics performing evaluations for patients with symptoms comparable to osteoporosis or bone fractures, the clinic is likely to encounter substantial market opportunities throughout the projection period.
Key Trends Rising consciousness regarding a healthy lifestyle that includes regular exercise and nutritious foods

Thyroid Gland Disorder Treatment Market:

Differentiating Aspects Thyroid Gland Disorder Treatment Market
CAGR (2023 to 2033) 3.4%
Market Valuation in 2023 2.44 billion
Projected Market Value in 2033 3.41 billion
Growth Factors The primary drivers driving market expansion include a spike in the prevalence of thyroid gland problems, an increase in illness awareness programs, particularly in emerging countries, and the development of potent combination pharmacological regimens to treat thyroid gland disorder.
Opportunities An rise in collaboration partnerships between private and public organizations to raise thyroid management knowledge among medical specialists and patients.
Key Trends Pharmaceutical businesses are taking steps to assist initiatives to promote awareness or to employ promotional techniques to raise consciousness.

Country-wise Insights

What are the Prospects of Adoption for Hypoparathyroidism Treatments in the United States?

United States to Take Over the North American Market

NATPARA (parathyroid hormone), is a recombinant hormonal therapy approved in the United States for the treatment of hypoparathyroidism. It is prescribed to patients who do not show positive results from standard therapies including calcium supplements and vitamin D.

In September 2019, Takeda Pharmaceutical Company Limited announced the recall for all its doses of NATPARA injections in the United States This recall was attributed to the presence of small rubber particles in solution samples, which originated from the rubber septum of the NATPARA cartridge.

This recall of injectable PTH in the United States has created distress among the patients and had a significant impact on treatment cycles. Around 2,700 patients have been affected by the shortage. Patients who are currently being treated with the therapy, have been pushed back to oral medications including calcium supplements and activated vitamin D to control their symptoms.

This transition has created a negative impact on disease management, leading some patients to hospitalization because of severe hypocalcemia. Further, manufacturers anticipate that the PTH injectable will require another year to return to the market. United State has emerged as a leading market, held over 37.7% of the total demand registered in 2022.

Why is Germany leading the Europe Hypoparathyroidism Treatment Market?

High Incidence of Parathyroid Diseases in Germany to Propel The Market Growth

Factors such as rising occurrences of parathyroid diseases, rising government initiatives, increasing medical care expenditure, better regulatory scenarios, and rising reimbursement policies and funding are persistently aiding the expansion of the hypoparathyroidism treatment market in Germany. As indicated by the information proposed by Eurostat, it is seen that among the EU Member States, the largest share of medical care expenditure was recorded in Germany in 2019.

Further, growing approvals and orphan drug designation from the European Commission (EC), increasing candidates in clinical trials for the development of hormonal therapy, presence of pharmaceutical players, which leads to better availability of products across the continent, are some of the factors that are responsible for making Germany, one of the largest market for hypoparathyroidism in Europe. Germany held a market share of 8.2% in 2022.

How Are Government Initiatives Boosting Hypoparathyroidism Treatment Market in India?

Adoption of Sophisticated Technology to Raise The Market Demand in India

Implementation of government programs aimed at offering affordable and quality healthcare is expected to complement the growth of India's biopharma industry, in turn creating opportunities for the hypoparathyroidism treatment market. Increasing adoption of technologically advanced treatment and rising awareness among people in India is fuelling the demand for hypoparathyroidism treatment.

India is also considered one of the top destinations of thyroid related disorders in the world, increasing the need for the Hypoparathyroidism Treatment market in the region. Increasing patient pool due to the rise in population, emergence of new diseases, and lifestyle changes are also boosting demand for biopharmaceuticals, which is expected to provide a high opportunity for providers of hypoparathyroidism treatment. The market in the India is poised to grow at a CAGR of 8.6% over the upcoming decades.

Category-wise Insights

How are Calcium Supplements Contributing to Market Revenue?

Calcium Supplements Segment to Grow Owing to The Lowered Side Effects

Hypoparathyroidism is characterized by low parathyroid hormone secretions which results in low calcium levels in the body. Calcium supplements are preferred as the first line of treatment by doctors to normalize the deficiency.

These supplements show a reduced risk of side effects as compared to hormonal therapy. The recent United States recall of the NATPARA compelled patients to opt for oral medication such as calcium supplements to treat the symptoms. These factors will drive demand for calcium supplements, accounting for the largest share of the global market. The calcium supplements segment accounted for a market revenue of 38.29% in 2022.

Which is the Preferred Route of Administration for Hypoparathyroidism Treatment?

Oral Segment to Dominate the Industry

The oral segment by route of administration, held the highest market share due to rising product launches and the presence of a solid pipeline. Various factors like a rapid delivery of drugs, high efficacy, and a higher rate of bioavailability are projected to impel the oral segment development. For drugs having medium to high oral availability, the oral route of administration is effective.

Oral treatments limit the utilization of central lines for intravenous drug administration and accordingly, decrease the danger of complications related to it and also a hospital stay. The advancement of promising new medications and potential clinical pipeline applicants are a portion of the major factors expected to boost segment development. The oral segment held a market revenue of 66.67% in 2022.

What is the share of Hospital & Retail Sales in the global Hypoparathyroidism Market?

Hospital Segment is to Expand Owing to The Rapid Delivery of Medications

The hospital and retail sales are expected to show the maximum share in the market among all distribution channels due to the increasing number of facilities and easy accessibility to patients. Also, the quick delivery of medicines is one of the major factors driving the market growth during the forecast period.

As there are rising numbers of cases of hypoparathyroidism, there is increasing demand for faster accessibility and availability of medicine to treat the disorder as rapidly as possible. Thus, hospitals and retail providers can provide medicines to patients at a faster rate which in turn increases the hypoparathyroidism treatment market.

Competitive Landscape

The global hypoparathyroidism treatment market is dominated by top manufacturers -Takeda Pharmaceutical Company Limited., Entera Bio Ltd., F. Hoffmann-La Roche Ltd, Amgen Inc., and Ascendis Pharma A/S Manufacturers are focusing on enhancing their global and regional presence through acquisitions and collaboration strategies.

  • In January 2019, Takeda Pharmaceutical Company acquired Shire plc. With this aquisition, Takeda strengthened its geographic presence in the United States, which is one of the key markets for biopharmaceuticals. Also, the acquisition of Shire has strengthened Takeda’s product portfolio and provided it with a leading position in GI, neuroscience, rare diseases, oncology, and PDT.
  • Ascendis Pharma established VISEN Pharmaceuticals, in November 2018, and collaborated to develop, manufacture, and commercialize the company’s TransCon Endocrinology Rare disease therapies in Greater China. This includes mainland China, Hong Kong, Macau, and Taiwan. Such collaborations are anticipated to expand TransCon PTH’s reach in Asian economies.
  • In March 2021, BridgeBio Pharma announced positive outcomes from the 2nd stage trial of its new drug Encaleret. As a part of hypoparathyroidism treatments, the drug has shown effectiveness among patients with autosomal dominant hypocalcemia type 1.
  • In May 2023, Amolyt Pharma disclosed an oral presentation at the 25th European Congress of Endocrinology (ECE) 2023. The presentation emphasizes the potential benefits of eneboparatide as a therapy for hypoparathyroidism, a condition in which numerous people have or are susceptible for acquiring osteopenia and osteoporosis.
  • The Food and Drug Administration (FDA) approved for Priority Assessment a new drug application (NDA) for TransConTM PTH (palopegteriparatide) in adults diagnosed with hypoparathyroidism in November 2022.

Scope of Report

Attribute Details
Forecast Period 2023 to 2033
Historical Data Available for 2018 to 2022
Hypoparathyroidism Treatment Market Value (2023) US$ 841.9 million
Hypoparathyroidism Treatment Market Expected Value (2033) US$ 1,767.4 million
Market Analysis US$ million for Value
Key Regions Covered
  • North America
  • Latin America
  • Europe
  • East Asia
  • South Asia
  • Oceania
  • Middle East & Africa
Key Countries Covered
  • United States
  • Canada
  • Brazil
  • Mexico
  • Germany
  • United Kingdom
  • France
  • Spain
  • Italy
  • India
  • Malaysia
  • Singapore
  • Thailand
  • China
  • Japan
  • South Korea
  • Australia
  • New Zealand
  • GCC Countries
  • South Africa
  • Israel
Key Segments Covered
  • Product Type
  • Route of Administration
  • Distribution Channel
  • Region
Key Companies Profiled
  • Takeda Pharmaceutical Company Limited.
  • Entera Bio Ltd.
  • Amgen Inc.
  • Ascendis Pharma A/S
  • F. Hoffmann-La Roche Ltd
  • ProLynx, Inc.
  • Extend Biosciences, Inc.
  • BionPharma Inc.
  • Teva Pharmaceuticals Ltd.
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Hypoparathyroidism Treatment Market Segmentation

By Product Type:

  • Parathyroid Hormone
    • Natpara
    • Others
  • Vitamin D Analogue
    • Vitamin D2
    • Vitamin D3
  • Calcium Supplements

By Route of Administration:

  • Oral
  • Parenteral

By Distribution Channel:

  • Hospital Pharmacies
  • Retail Pharmacies
  • Online Sales

By Region:

  • North America
  • Latin America
  • Europe
  • East Asia
  • South Asia
  • Oceania
  • Middle East & Africa

Frequently Asked Questions

What is the expected valuation of the global hypoparathyroidism treatment market in 2023?

The global hypoparathyroidism treatment market is estimated to be valued at US$ 841.9 million in 2023.

What was the growth rate of the global hypoparathyroidism treatment market from 2017 to 2022?

The global market for hypoparathyroidism treatment rose at a CAGR of 5.1% from 2017 to 2022

What is the growth outlook for the global hypoparathyroidism treatment market until 2033?

The global hypoparathyroidism treatment market is expected to progress at a CAGR of 7.7% from 2023 to 2033

What is the CAGR of the market for hypoparathyroidism treatment in India?

The market in India is projected to rise at a CAGR of 8.6% over the upcoming decade

What is the expected valuation of the global hypoparathyroidism treatment market in 2033?

The global hypoparathyroidism treatment market is predicted to account for US$ 1,767.4 million by 2033.

Which is the most lucrative market for hypoparathyroidism treatment?

United States has emerged as a leading market, holding over 37.7% of the total demand registered in 2022.

What is the CAGR of the hypoparathyroidism treatment market in China?

The market in China is projected to rise at a CAGR of 7.9% over the upcoming decade

What is the market share of calcium supplements treatment?

The calcium supplements segment accounted for a market revenue of 38.29% in 2022.

Table of Content

1. Executive Summary

    1.1. Global Market Outlook

    1.2. Demand-side Trends

    1.3. Supply-side Trends

    1.4. Technology Roadmap Analysis

    1.5. Analysis and Recommendations

2. Market Overview

    2.1. Market Coverage / Taxonomy

    2.2. Market Definition / Scope / Limitations

3. Market Background

    3.1. Market Dynamics

        3.1.1. Drivers

        3.1.2. Restraints

        3.1.3. Opportunity

        3.1.4. Trends

    3.2. Scenario Forecast

        3.2.1. Demand in Optimistic Scenario

        3.2.2. Demand in Likely Scenario

        3.2.3. Demand in Conservative Scenario

    3.3. Opportunity Map Analysis

    3.4. Investment Feasibility Matrix

    3.5. PESTLE and Porter’s Analysis

    3.6. Regulatory Landscape

        3.6.1. By Key Regions

        3.6.2. By Key Countries

    3.7. Regional Parent Market Outlook

4. Global Market Analysis 2018 to 2022 and Forecast, 2023 to 2033

    4.1. Historical Market Size Value (US$ Million) Analysis, 2018 to 2022

    4.2. Current and Future Market Size Value (US$ Million) Projections, 2023 to 2033

        4.2.1. Y-o-Y Growth Trend Analysis

        4.2.2. Absolute $ Opportunity Analysis

5. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Product Type

    5.1. Introduction / Key Findings

    5.2. Historical Market Size Value (US$ Million) Analysis By Product Type, 2018 to 2022

    5.3. Current and Future Market Size Value (US$ Million) Analysis and Forecast By Product Type, 2023 to 2033

        5.3.1. Parathyroid Hormone

            5.3.1.1. Natpara

            5.3.1.2. Others

        5.3.2. Vitamin D Analogue

            5.3.2.1. Vitamin D2

            5.3.2.2. Vitamin D3

        5.3.3. Calcium Supplements

    5.4. Y-o-Y Growth Trend Analysis By Product Type, 2018 to 2022

    5.5. Absolute $ Opportunity Analysis By Product Type, 2023 to 2033

6. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Route of Administration

    6.1. Introduction / Key Findings

    6.2. Historical Market Size Value (US$ Million) Analysis By Route of Administration, 2018 to 2022

    6.3. Current and Future Market Size Value (US$ Million) Analysis and Forecast By Route of Administration, 2023 to 2033

        6.3.1. Oral

        6.3.2. Parenteral

    6.4. Y-o-Y Growth Trend Analysis By Route of Administration, 2018 to 2022

    6.5. Absolute $ Opportunity Analysis By Route of Administration, 2023 to 2033

7. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Distribution Channel 

    7.1. Introduction / Key Findings

    7.2. Historical Market Size Value (US$ Million) Analysis By Distribution Channel, 2018 to 2022

    7.3. Current and Future Market Size Value (US$ Million) Analysis and Forecast By Distribution Channel, 2023 to 2033

        7.3.1. Hospital Pharmacies

        7.3.2. Retail Pharmacies

        7.3.3. Online Sales

    7.4. Y-o-Y Growth Trend Analysis By Distribution Channel, 2018 to 2022

    7.5. Absolute $ Opportunity Analysis By Distribution Channel, 2023 to 2033

8. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Region

    8.1. Introduction

    8.2. Historical Market Size Value (US$ Million) Analysis By Region, 2018 to 2022

    8.3. Current Market Size Value (US$ Million) Analysis and Forecast By Region, 2023 to 2033

        8.3.1. North America

        8.3.2. Latin America

        8.3.3. Europe

        8.3.4. South Asia

        8.3.5. East Asia

        8.3.6. Oceania

        8.3.7. MEA

    8.4. Market Attractiveness Analysis By Region

9. North America Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country

    9.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022

    9.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033

        9.2.1. By Country

            9.2.1.1. USA

            9.2.1.2. Canada

        9.2.2. By Product Type

        9.2.3. By Route of Administration

        9.2.4. By Distribution Channel

    9.3. Market Attractiveness Analysis

        9.3.1. By Country

        9.3.2. By Product Type

        9.3.3. By Route of Administration

        9.3.4. By Distribution Channel

    9.4. Key Takeaways

10. Latin America Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country

    10.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022

    10.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033

        10.2.1. By Country

            10.2.1.1. Brazil

            10.2.1.2. Mexico

            10.2.1.3. Rest of Latin America

        10.2.2. By Product Type

        10.2.3. By Route of Administration

        10.2.4. By Distribution Channel

    10.3. Market Attractiveness Analysis

        10.3.1. By Country

        10.3.2. By Product Type

        10.3.3. By Route of Administration

        10.3.4. By Distribution Channel

    10.4. Key Takeaways

11. Europe Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country

    11.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022

    11.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033

        11.2.1. By Country

            11.2.1.1. Germany

            11.2.1.2. UK

            11.2.1.3. France

            11.2.1.4. Spain

            11.2.1.5. Italy

            11.2.1.6. Rest of Europe

        11.2.2. By Product Type

        11.2.3. By Route of Administration

        11.2.4. By Distribution Channel

    11.3. Market Attractiveness Analysis

        11.3.1. By Country

        11.3.2. By Product Type

        11.3.3. By Route of Administration

        11.3.4. By Distribution Channel

    11.4. Key Takeaways

12. South Asia Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country

    12.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022

    12.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033

        12.2.1. By Country

            12.2.1.1. India

            12.2.1.2. Malaysia

            12.2.1.3. Singapore

            12.2.1.4. Thailand

            12.2.1.5. Rest of South Asia

        12.2.2. By Product Type

        12.2.3. By Route of Administration

        12.2.4. By Distribution Channel

    12.3. Market Attractiveness Analysis

        12.3.1. By Country

        12.3.2. By Product Type

        12.3.3. By Route of Administration

        12.3.4. By Distribution Channel

    12.4. Key Takeaways

13. East Asia Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country

    13.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022

    13.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033

        13.2.1. By Country

            13.2.1.1. China

            13.2.1.2. Japan

            13.2.1.3. South Korea

        13.2.2. By Product Type

        13.2.3. By Route of Administration

        13.2.4. By Distribution Channel

    13.3. Market Attractiveness Analysis

        13.3.1. By Country

        13.3.2. By Product Type

        13.3.3. By Route of Administration

        13.3.4. By Distribution Channel

    13.4. Key Takeaways

14. Oceania Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country

    14.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022

    14.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033

        14.2.1. By Country

            14.2.1.1. Australia

            14.2.1.2. New Zealand

        14.2.2. By Product Type

        14.2.3. By Route of Administration

        14.2.4. By Distribution Channel

    14.3. Market Attractiveness Analysis

        14.3.1. By Country

        14.3.2. By Product Type

        14.3.3. By Route of Administration

        14.3.4. By Distribution Channel

    14.4. Key Takeaways

15. MEA Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country

    15.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022

    15.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033

        15.2.1. By Country

            15.2.1.1. GCC Countries

            15.2.1.2. South Africa

            15.2.1.3. Israel

            15.2.1.4. Rest of MEA

        15.2.2. By Product Type

        15.2.3. By Route of Administration

        15.2.4. By Distribution Channel

    15.3. Market Attractiveness Analysis

        15.3.1. By Country

        15.3.2. By Product Type

        15.3.3. By Route of Administration

        15.3.4. By Distribution Channel

    15.4. Key Takeaways

16. Key Countries Market Analysis

    16.1. USA

        16.1.1. Pricing Analysis

        16.1.2. Market Share Analysis, 2022

            16.1.2.1. By Product Type

            16.1.2.2. By Route of Administration

            16.1.2.3. By Distribution Channel

    16.2. Canada

        16.2.1. Pricing Analysis

        16.2.2. Market Share Analysis, 2022

            16.2.2.1. By Product Type

            16.2.2.2. By Route of Administration

            16.2.2.3. By Distribution Channel

    16.3. Brazil

        16.3.1. Pricing Analysis

        16.3.2. Market Share Analysis, 2022

            16.3.2.1. By Product Type

            16.3.2.2. By Route of Administration

            16.3.2.3. By Distribution Channel

    16.4. Mexico

        16.4.1. Pricing Analysis

        16.4.2. Market Share Analysis, 2022

            16.4.2.1. By Product Type

            16.4.2.2. By Route of Administration

            16.4.2.3. By Distribution Channel

    16.5. Germany

        16.5.1. Pricing Analysis

        16.5.2. Market Share Analysis, 2022

            16.5.2.1. By Product Type

            16.5.2.2. By Route of Administration

            16.5.2.3. By Distribution Channel

    16.6. UK

        16.6.1. Pricing Analysis

        16.6.2. Market Share Analysis, 2022

            16.6.2.1. By Product Type

            16.6.2.2. By Route of Administration

            16.6.2.3. By Distribution Channel

    16.7. France

        16.7.1. Pricing Analysis

        16.7.2. Market Share Analysis, 2022

            16.7.2.1. By Product Type

            16.7.2.2. By Route of Administration

            16.7.2.3. By Distribution Channel

    16.8. Spain

        16.8.1. Pricing Analysis

        16.8.2. Market Share Analysis, 2022

            16.8.2.1. By Product Type

            16.8.2.2. By Route of Administration

            16.8.2.3. By Distribution Channel

    16.9. Italy

        16.9.1. Pricing Analysis

        16.9.2. Market Share Analysis, 2022

            16.9.2.1. By Product Type

            16.9.2.2. By Route of Administration

            16.9.2.3. By Distribution Channel

    16.10. India

        16.10.1. Pricing Analysis

        16.10.2. Market Share Analysis, 2022

            16.10.2.1. By Product Type

            16.10.2.2. By Route of Administration

            16.10.2.3. By Distribution Channel

    16.11. Malaysia

        16.11.1. Pricing Analysis

        16.11.2. Market Share Analysis, 2022

            16.11.2.1. By Product Type

            16.11.2.2. By Route of Administration

            16.11.2.3. By Distribution Channel

    16.12. Singapore

        16.12.1. Pricing Analysis

        16.12.2. Market Share Analysis, 2022

            16.12.2.1. By Product Type

            16.12.2.2. By Route of Administration

            16.12.2.3. By Distribution Channel

    16.13. Thailand

        16.13.1. Pricing Analysis

        16.13.2. Market Share Analysis, 2022

            16.13.2.1. By Product Type

            16.13.2.2. By Route of Administration

            16.13.2.3. By Distribution Channel

    16.14. China

        16.14.1. Pricing Analysis

        16.14.2. Market Share Analysis, 2022

            16.14.2.1. By Product Type

            16.14.2.2. By Route of Administration

            16.14.2.3. By Distribution Channel

    16.15. Japan

        16.15.1. Pricing Analysis

        16.15.2. Market Share Analysis, 2022

            16.15.2.1. By Product Type

            16.15.2.2. By Route of Administration

            16.15.2.3. By Distribution Channel

    16.16. South Korea

        16.16.1. Pricing Analysis

        16.16.2. Market Share Analysis, 2022

            16.16.2.1. By Product Type

            16.16.2.2. By Route of Administration

            16.16.2.3. By Distribution Channel

    16.17. Australia

        16.17.1. Pricing Analysis

        16.17.2. Market Share Analysis, 2022

            16.17.2.1. By Product Type

            16.17.2.2. By Route of Administration

            16.17.2.3. By Distribution Channel

    16.18. New Zealand

        16.18.1. Pricing Analysis

        16.18.2. Market Share Analysis, 2022

            16.18.2.1. By Product Type

            16.18.2.2. By Route of Administration

            16.18.2.3. By Distribution Channel

    16.19. GCC Countries

        16.19.1. Pricing Analysis

        16.19.2. Market Share Analysis, 2022

            16.19.2.1. By Product Type

            16.19.2.2. By Route of Administration

            16.19.2.3. By Distribution Channel

    16.20. South Africa

        16.20.1. Pricing Analysis

        16.20.2. Market Share Analysis, 2022

            16.20.2.1. By Product Type

            16.20.2.2. By Route of Administration

            16.20.2.3. By Distribution Channel

    16.21. Israel

        16.21.1. Pricing Analysis

        16.21.2. Market Share Analysis, 2022

            16.21.2.1. By Product Type

            16.21.2.2. By Route of Administration

            16.21.2.3. By Distribution Channel

17. Market Structure Analysis

    17.1. Competition Dashboard

    17.2. Competition Benchmarking

    17.3. Market Share Analysis of Top Players

        17.3.1. By Regional

        17.3.2. By Product Type

        17.3.3. By Route of Administration

        17.3.4. By Distribution Channel

18. Competition Analysis

    18.1. Competition Deep Dive

        18.1.1. Takeda Pharmaceutical Company Limited.

            18.1.1.1. Overview

            18.1.1.2. Product Portfolio

            18.1.1.3. Profitability by Market Segments

            18.1.1.4. Sales Footprint

            18.1.1.5. Strategy Overview

                18.1.1.5.1. Marketing Strategy

        18.1.2. Entera Bio Ltd.

            18.1.2.1. Overview

            18.1.2.2. Product Portfolio

            18.1.2.3. Profitability by Market Segments

            18.1.2.4. Sales Footprint

            18.1.2.5. Strategy Overview

                18.1.2.5.1. Marketing Strategy

        18.1.3. Amgen Inc.

            18.1.3.1. Overview

            18.1.3.2. Product Portfolio

            18.1.3.3. Profitability by Market Segments

            18.1.3.4. Sales Footprint

            18.1.3.5. Strategy Overview

                18.1.3.5.1. Marketing Strategy

        18.1.4. Ascendis Pharma A/S

            18.1.4.1. Overview

            18.1.4.2. Product Portfolio

            18.1.4.3. Profitability by Market Segments

            18.1.4.4. Sales Footprint

            18.1.4.5. Strategy Overview

                18.1.4.5.1. Marketing Strategy

        18.1.5. F. Hoffmann-La Roche Ltd

            18.1.5.1. Overview

            18.1.5.2. Product Portfolio

            18.1.5.3. Profitability by Market Segments

            18.1.5.4. Sales Footprint

            18.1.5.5. Strategy Overview

                18.1.5.5.1. Marketing Strategy

        18.1.6. ProLynx, Inc.

            18.1.6.1. Overview

            18.1.6.2. Product Portfolio

            18.1.6.3. Profitability by Market Segments

            18.1.6.4. Sales Footprint

            18.1.6.5. Strategy Overview

                18.1.6.5.1. Marketing Strategy

        18.1.7. Extend Biosciences, Inc.

            18.1.7.1. Overview

            18.1.7.2. Product Portfolio

            18.1.7.3. Profitability by Market Segments

            18.1.7.4. Sales Footprint

            18.1.7.5. Strategy Overview

                18.1.7.5.1. Marketing Strategy

        18.1.8. BionPharma Inc.

            18.1.8.1. Overview

            18.1.8.2. Product Portfolio

            18.1.8.3. Profitability by Market Segments

            18.1.8.4. Sales Footprint

            18.1.8.5. Strategy Overview

                18.1.8.5.1. Marketing Strategy

        18.1.9. Sun Pharmaceutical Industries Ltd.

            18.1.9.1. Overview

            18.1.9.2. Product Portfolio

            18.1.9.3. Profitability by Market Segments

            18.1.9.4. Sales Footprint

            18.1.9.5. Strategy Overview

                18.1.9.5.1. Marketing Strategy

        18.1.10. Teva Pharmaceuticals Ltd.

            18.1.10.1. Overview

            18.1.10.2. Product Portfolio

            18.1.10.3. Profitability by Market Segments

            18.1.10.4. Sales Footprint

            18.1.10.5. Strategy Overview

                18.1.10.5.1. Marketing Strategy

19. Assumptions & Acronyms Used

20. Research Methodology

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