Nucleic Acid and Gene Therapies in Neuromuscular Disorders Market
Nucleic Acid And Gene Therapies In Neuromuscular Disorders Market by Therapy, Application & Region | Forecast 2023 to 2033
Factors such as increase in product approvals, surge in funding for gene therapy research, and strong product pipeline are expected to augment the growth of the nucleic acid and gene therapies in neuromuscular disorders market over the analysis period.
Nucleic Acid And Gene Therapies In Neuromuscular Disorders Market Snapshot (2023 to 2033)
The global Nucleic Acid And Gene Therapies In Neuromuscular Disorders market size is expected to be valued at US$ 7.88 Billion in 2023. With the increasingly high incidence of cancer and other target diseases, the overall demand for Nucleic Acid And Gene Therapies In Neuromuscular Disorders is projected to grow at a CAGR of 9.5% between 2023 and 2033, totaling around US$ 19.52 Billion by 2033.
Data Points
Key Statistics
Nucleic Acid And Gene Therapies In Neuromuscular Disorders Market Value 2023
US$ 7.88 Billion
Nucleic Acid And Gene Therapies In Neuromuscular Disorders Market Projected Value (2033)
US$ 19.52 Billion
Nucleic Acid And Gene Therapies In Neuromuscular Disorders Market CAGR (2023 to 2033)
9.5%
According to the analysis of Future Market Insights, the Nucleic Acid And Gene Therapies In the Neuromuscular Disorders market are expected to fuel over the analysis period, attributed to the factors such as a rise in the number of drug approvals, which will lead to the expansion of the market growth.
Moreover, owing to the rapidly progressive nature of the disease, the treatments using drugs are not effective and do not stop the disease progression. This leads the vendors to conduct research on the development of gene therapies and antisense therapies that can stop the progression of the disease and increase the life expectancy of the patients.
An upsurge in technological advances is a major factor that is projected to contribute significantly to the research and development of novel therapeutics for neuromuscular diseases. In addition, the lack of efficacy and non-disease-modifying drugs for the treatment are leading the vendors to focus on identifying the benefits of regenerative therapies as a potential treatment option.
Furthermore, the advent of next-generation genetic sequencing technology focuses on sequencing the human genome, while significantly reducing the associated costs. This, in turn, results in the market witnessing advances in the identification of mutated genes that cause neuromuscular diseases. This development is expected to have a positive impact on overall market growth.
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Nucleic Acid And Gene Therapies In Neuromuscular Disorders Demand Analysis (2018 to 2022) Vs Market Outlook (2023 to 2033)
The global demand for Nucleic Acid And Gene Therapies In Neuromuscular Disorders is projected to increase at a CAGR of 9.5% during the forecast period between 2023 and 2033, reaching a total of US$ 19.52 Billion in 2033, according to a report from Future Market Insights (FMI). From 2018 to 2022, sales witnessed significant growth, registering a CAGR of 3.5%.
According to Future Market Insights, a market research and competitive intelligence provider, the Nucleic Acid And Gene Therapies In the Neuromuscular Disorders market were valued at US$ 7.19 Billion in 2022.
Factors including a surge in government initiatives to ensure early diagnosis, an increase in awareness about genetic disorders, enhanced healthcare infrastructure, and a rise in research and development activities are anticipated to propel the growth of nucleic acid and gene therapies in the neuromuscular disorders market during the forecast period.
According to a study conducted in 2014, the prevalence rate of neuromuscular disorders was between 1 and 10 per 100,000, except for multifocal motor neuropathy, Lambert-Eaton myasthenic syndrome, Emery-Dreifuss dystrophy, oculopharyngeal muscular dystrophy, and congenital muscular dystrophies, which was <1/100,000. Post-polio syndrome and Charcot-Marie-Tooth disease had a prevalence of >10/100,000.
Diagnosis of neuromuscular disorders is performed through physical examination as well as certain diagnostic tests. A physician runs a complete medical history assessment, in order to assess the condition of a patient to determine if any family member had previously had symptoms of neuromuscular disorders. Currently, there is no cure for neuromuscular disorders. However, research is being done on genetic therapies and new medications to develop a cure. These are lifelong disorders and cannot be cured completely, but can be managed to help individuals to maximize their capabilities.
Which Drivers underpin Nucleic Acid And Gene Therapies In Neuromuscular Disorders Industry Expansion?
Rise in R&D Activitiesto Fuel the Market Growth
Neuromuscular diseases are a broad category of disorders that cause progressive motor function impairment. Motor neurons, skeletal muscle, or their synaptic connection, the neuromuscular junction, are the most common Neuromuscular Disorders. MNs [e.g., amyotrophic lateral sclerosis caused by direct loss or retrograde degeneration of MNs], muscle [e.g., Duchenne muscular dystrophy or myotonic dystrophy], NMJs [e.g., myasthenia gravis or congenital myasthenic syndromes], or a combination of these [e.g. (e.g., Pompe disease).
Moreover, regardless of its source, the structural and functional deficit in a targeted tissue will resonate throughout the motor unit, resulting in multiple shared symptoms among different Neuromuscular Disorders.
Methods to differentiate hiPSCs into neuronal cells have advanced rapidly in the last decade, because of an increased understanding of early neural development and the commitment of neuro progenitor cells to highly specialized neural subtypes, including MNs. The MNs are found throughout the CNS and are divided into upper MNs (UMNs) and lower MNs (LMNs), which are developmentally and genetically distinct despite their shared nomenclature. Different NMDs can target UMNs and LMNs, making their distinction important when modeling NMDs. The cerebral cortex's pre-motor and primary motor regions are where UMNs originate. As a result, many recent breakthroughs in neuromuscular disease therapy development have been made.
There are approximately 200 products in the pipeline for neuromuscular disorders, with a roughly 50:50 ratio of preclinical to clinical development. Most target amyotrophic lateral sclerosis (ALS) and Duchenne's muscular dystrophy (DMD). Recent technological advancements have aided the development of several different types of therapies. In 2018, small molecules (targeting receptor modulation, epigenetic reprogramming, redox metabolism, and other mechanisms), gene therapy, and antisense oligonucleotides accounted for nearly half of the nearly 200 potential therapies for neuromuscular diseases under development (Aitken et al., 2018). The US Food and Drug Administration recently approved ASO and gene therapy. Thus, these factors are anticipated to fuel market growth in the forthcoming years.
Novel Drug Approvals to Accelerate the Market Growth
Novel drug approvals are one of the key factors that are projected to augment the growth of nucleic acid and gene therapies in the neuromuscular disorders market. There has been an increase in drug approvals in the market for treating various neuromuscular indications in recent years. This is attributed to the advanced research being conducted on highly morbid and progressive indications.
Spinal muscular atrophy is one of the major neuromuscular diseases for which the market has witnessed therapeutic approvals. Spinal muscular atrophy is morbid and rapidly progressive neuromuscular. It is caused by the death of a type of nerve cell, called motor neurons, in the spinal cord. Treatments using drugs are not effective and do not stop the disease progression due to the rapidly progressive nature of the disease.
To overcome this challenge, various vendors are conducting research on the development of novel gene therapies and antisense therapies that can stop the progression of the disease and increase the life expectancy of patients. Hence, these factors are expected to accelerate the growth of the market growth during the forecast period.
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Which Factors are limiting the Growth of Nucleic Acid And Gene Therapies In Neuromuscular Disorders Market?
Exorbitant Treatment Costs to Restrain the Market Growth
Regardless of the increasing prevalence of chronic disorders such as SMA and cancer, the treatment method for neuromuscular disorders is extremely expensive. The method is majorly advertised as a single-dose treatment regime that reverses the genetic dysfunction in the patient’s body. As per Novartis AG, a single dose of Kymriah, the therapy cancer drug costs a whopping USD 475,000. The same drug is priced at USD 306,000 in Japan.
This expensive therapy has also encouraged reluctance to reimburse the treatment method by some insurance companies. This is one of the major factors that is expected to hinder the growth of nucleic acid and gene therapies in the neuromuscular disorders market during the forecast period.
Additionally, low awareness in developing countries and a lack of diagnostic facilities are other factors that will hamper market growth in the near future.
Side Effects Associated with Neuromuscular Therapeutics to Limit the Market Growth
Myasthenia gravis (MG) is a neuromuscular junction disorder that causes varying degrees of weakness in the body's skeletal muscles. Although there is currently no cure for MG, traditional therapies such as acetylcholinesterase inhibitors as well as immunomodulating therapies (corticosteroids, azathioprine, and mycophenolate mofetil) enable most patients to live productive lives with an average life expectancy.
However, these therapies are associated with side effects such as nausea, vomiting, gastrointestinal (GI) upset, increased infection risk, weight gain, and liver damage, which can deter patients from using the medications.
Additionally, poor adherence is also a result of unsatisfactory treatment outcomes with traditional MG therapies, with 23 percent of patients reporting poor treatment compliance. Despite this, patient-reported information on the exact nature, duration, and severity of these side effects is scarce. Moreover, stringent regulations imposed by governments are another major factor that is expected to impede market growth over the analysis period.
Region-wise Insights
Will North America Continue Dominance in the Global Nucleic Acid And Gene Therapies In Neuromuscular Disorders Market?
Better Healthcare Infrastructure in the Region to Fuel the Market Growth
The Nucleic Acid And Gene Therapies In Neuromuscular Disorders Market in North America is expected to accumulate the highest market share of 46% in 2023.
Factors such as the increasing patient population, presence of major market players in North America, and better healthcare infrastructure are projected to boost the regional market growth during the forecast period. Moreover, increasing approvals of novel nucleic acid treatments and the availability of nucleic acid extraction technology are other factors that are expected to accelerate the market growth in the region. For instance, neuromuscular diseases (NMDs) are a broad category of disorders that affect an estimated 250,000 people in the United States.
In addition, in December 2021, Vyvgart (efgartigimod) received approval from the US Food and Drug Administration for the treatment of generalized myasthenia gravis (gMG) in adults who test positive for the anti-acetylcholine receptor (AChR) antibody. The region is expected to hold the highest CAGR of 9.4% during the forecast period.
How Will Growth of the Nucleic Acid And Gene Therapies In the Neuromuscular Disorders Market unfold in Asia Pacific?
Increasing Population in the Region to Fuel the Market Growth
The Nucleic Acid And Gene Therapies In Neuromuscular Disorders Market in Asia Pacific are expected to accumulate the highest market share of 44% in 2023.
The Asia Pacific hypophosphatasia market is anticipated to register significant growth during the analysis period, attributed to factors such as an increase in population, high acceptance of new treatment methodologies, as well as improvement in healthcare infrastructure in countries such as India. Furthermore, the rise in focus of major market players in Asia Pacific is another major factor that will propel the revenue share of the regional market during the forecast period.
An increase in investment, strong collaboration among research institutes and private players, and high awareness regarding the treatment are other factors that are anticipated to escalate the growth of the market in the region in the near future. The region is expected to hold the highest CAGR of 9.3% during the forecast period.
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Category-wise Insights
By Therapy, which Nucleic Acid And Gene Therapies In Neuromuscular Disorders Category dominate?
Spinal Muscular Atrophy Segment to Drive the Nucleic Acid And Gene Therapies In Neuromuscular Disorders Market
Based on the Therapy, the Spinal Muscular Atrophy segment is expected to witness a significant growth of 46% in 2022, and the trend is expected to continue during the forecast period, expanding at a rapid rate of 9.4% CAGR over the analysis period.
The segment’s growth is attributed to the SMA being a good example of a monogenic disease that currently has an AAV9-based vector gene therapy as a therapeutic option. In addition, the rise in the incidence of cancer and other target diseases, the availability of reimbursement policies, as well as the increase in funding for gene therapy research are other major factors escalating the growth of the segment.
By Application, which Nucleic Acid And Gene Therapies In Neuromuscular Disorders Category dominate?
Hospitals Segment to Drive the Nucleic Acid And Gene Therapies In Neuromuscular Disorders Market
Based on the Application, the hospital's segment is expected to witness a significant growth of 45% in 2022, and the trend is expected to continue during the forecast period, expanding at a rapid rate of 9.3% CAGR over the analysis period.
In terms of application, the hospital segment is expected to have the highest share of the market during the forecast period. The dominance is attributed to the high availability as well as the accessibility of the treatment methods in such facilities.
The Start-Up Ecosystem: How key Players are opening Frontiers for Future Growth?
Nucleic Acid And Gene Therapies In Neuromuscular Disorders Market startup players are adopting various marketing strategies such as new product launches, geographical expansion, mergers and acquisitions, partnerships, and collaboration to identify the interest of potential patients and create a larger customer base. For instance,
Founded in 2016, GenEdit is a developer of a drug-delivery system for genetic medicines. The company has developed a NanoGalaxy platform that contains non-viral, non-lipid, polymer nanoparticles to deliver genetic medicines to the needed tissue to treat disease.
Established in 2013, Spark Therapeutics is a fully integrated, commercial company committed to discovering, developing, and delivering gene therapies. Spark is the first company in the U.S. to receive FDA approval for gene therapy for a genetic disease. The company focused on breaking barriers for people and families affected by genetic diseases, including blindness, hemophilia, lysosomal storage disorders, and neurodegenerative disease.
CRISPR Therapeutics started in 2013, is a developer of solutions for treating human genetic diseases by using genome editing technology. It develops cures for serious human genetic diseases using CRISPR-CAS9. Its solution translates CRISPR-Cas9, a gene-editing technology into transformative medicines.
Who are the Leading Players in the Nucleic Acid And Gene Therapies In Neuromuscular Disorders Market?
Prominent players in the Nucleic Acid And Gene Therapies In Neuromuscular Disorders market are Pfizer, Inc., F. Hoffmann-La Roche Ltd., UCB Pharma, Biogen, Astellas Pharma, Inc., Novartis AG, Abbott Laboratories, Inc., and Sanofi, among others.
Recent Developments:
In April 2021, Genethon announced First Patient dosed in the Clinical Trial of Investigational Gene therapy GNT 0004 for Duchenne Muscular Dystrophy. The gene therapy (GNT 0004) is based on an adeno-associated virus (AAV) capsid and an optimized gene, a shortened version of the gene coding for dystrophin, the protein that is absent in patients with Duchenne muscular dystrophy.
In May 2019, AveXis, a Novartis company, announced that the US Food and Drug Administration (FDA) had approved Zolgensma® (onasemnogene abeparvovec-xioi) for the treatment of pediatric patients less than 2 years of age with spinal muscular atrophy (SMA) with bi-allelic mutations in the survival motor neuron 1 (SMN1) gene. Zolgensma is designed to address the genetic root cause of SMA by providing a functional copy of the human SMN gene to halt disease progression through sustained SMN protein expression with a single, one-time intravenous (IV) infusion. Zolgensma is the first and only gene therapy approved by the FDA for the treatment of SMA, including those who are pre-symptomatic at diagnosis.
Report Scope
Report Attribute
Details
Growth Rate
CAGR of 9.5% from 2023 to 2033
Market Value in 2023
US$ 7.88 Billion
Market Value in 2033
US$ 19.52 Billion
Base Year for Estimation
2022
Historical Data
2018 to 2022
Forecast Period
2023 to 2033
Quantitative Units
Revenue in US$ Billion and CAGR from 2023 to 2033
Report Coverage
Revenue Forecast, Company Ranking, Competitive Landscape, Growth Factors, Trends, and Pricing Analysis
Segments Covered
Disorder
Therapy
Application
Region
Regions Covered
North America
Europe
Asia Pacific
Latin America
Middle East & Africa (MEA)
Key Countries Profiled
The US
Canada
Brazil
Mexico
Germany
The UK
France
Spain
Italy
China
Japan
South Korea
Malaysia
Singapore
Australia
New Zealand
GCC
South Africa
Israel
Key Companies Profiled
Pfizer, Inc.
F. Hoffmann-La Roche Ltd.
UCB Pharma
Biogen
Astellas Pharma, Inc.
Novartis AG
Abbott Laboratories, Inc.
Sanofi
Key Segments Covered in the Nucleic Acid And Gene Therapies In Neuromuscular Disorders Industry Analysis
Nucleic Acid And Gene Therapies In Neuromuscular Disorders Market by Disorder:
Motor Neuron Diseases
Neuropathies
Neuromuscular Junction Disorders
Myopathies including Muscular Dystrophies
Nucleic Acid And Gene Therapies In Neuromuscular Disorders Market by Therapy:
AAV Gene Therapy
Postnatal Gene Therapy
Spinal Muscular Atrophy
Nucleic Acid And Gene Therapies In Neuromuscular Disorders Market by Application
Hospitals
Specialty Clinics
Ambulatory Surgery Centers
Nucleic Acid And Gene Therapies In Neuromuscular Disorders Market by Region
North America
Europe
Asia Pacific
Latin America
Middle East & Africa (MEA)
Frequently Asked Questions
What was the market value for Nucleic Acid And Gene Therapies In Neuromuscular Disorders in 2022?
As of 2022, the market for Nucleic Acid And Gene Therapies In Neuromuscular Disorders was valued at US$ 7.19 Billion, as per FMI
At what value did the Nucleic Acid And Gene Therapies In Neuromuscular Disorders Market close in 2023?
By 2023-end, sales of Nucleic Acid And Gene Therapies In Neuromuscular Disorders closed at a value of US$ 7.88 Billion
What was the last 4 years value CAGR for Nucleic Acid And Gene Therapies In Neuromuscular Disorders?
From 2018 to 2022, Nucleic Acid And Gene Therapies In Neuromuscular Disorders demand expanded at a CAGR of 3.5%
What is the projected forecast CAGR for the Nucleic Acid And Gene Therapies In Neuromuscular Disorders Industry from 2023-2033?
From 2023 to 2033, Nucleic Acid And Gene Therapies In Neuromuscular Disorders sales are expected to flourish at a CAGR of 9.5%
According to FMI, what is the anticipated market value for Nucleic Acid And Gene Therapies In Neuromuscular Disorders in 2033?
By 2033, the market value of Nucleic Acid And Gene Therapies In Neuromuscular Disorders is expected to reach US$ 19.52 Billion.
By Therapy, which category ranks first with regard to Nucleic Acid And Gene Therapies In Neuromuscular Disorders?
By Therapy, the Spinal Muscular Atrophy segment constitutes the bulk of market share of 46% in 2022.
By Application, which category ranks first with regard to Nucleic Acid And Gene Therapies In Neuromuscular Disorders?
By Application, the Hospitals segment dominates the market with a share of 45% in 2022.
Table of Content
1. Executive Summary | Nucleic Acid and Gene Therapies in Neuromuscular Disorders Market
1.1. Global Market Outlook
1.2. Demand-side Trends
1.3. Supply-side Trends
1.4. Technology Roadmap Analysis
1.5. Analysis and Recommendations
2. Market Overview
2.1. Market Coverage / Taxonomy
2.2. Market Definition / Scope / Limitations
3. Market Background
3.1. Market Dynamics
3.1.1. Drivers
3.1.2. Restraints
3.1.3. Opportunity
3.1.4. Trends
3.2. Scenario Forecast
3.2.1. Demand in Optimistic Scenario
3.2.2. Demand in Likely Scenario
3.2.3. Demand in Conservative Scenario
3.3. Opportunity Map Analysis
3.4. Investment Feasibility Matrix
3.5. PESTLE and Porter’s Analysis
3.6. Regulatory Landscape
3.6.1. By Key Regions
3.6.2. By Key Countries
3.7. Regional Parent Market Outlook
4. Global Market Analysis 2018 to 2022 and Forecast, 2023 to 2033
4.1. Historical Market Size Value (US$ Billion) Analysis, 2018 to 2022
4.2. Current and Future Market Size Value (US$ Billion) Projections, 2023 to 2033
4.2.1. Y-o-Y Growth Trend Analysis
4.2.2. Absolute $ Opportunity Analysis
5. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Disorder
5.1. Introduction / Key Findings
5.2. Historical Market Size Value (US$ Billion) Analysis By Disorder, 2018 to 2022
5.3. Current and Future Market Size Value (US$ Billion) Analysis and Forecast By Disorder, 2023 to 2033
5.3.1. Spinal Muscular Atrophy
5.3.2. Duchenne Muscular Dystrophy
5.3.3. Limb-girdle Muscular Dystrophy
5.3.4. Myotubular Myopathy
5.3.5. Hereditary Motor and Sensory Neuropathy Type
5.3.6. Amyloid Transthyretin
5.4. Y-o-Y Growth Trend Analysis By Disorder, 2018 to 2022
5.5. Absolute $ Opportunity Analysis By Disorder, 2023 to 2033
6. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Therapy
6.1. Introduction / Key Findings
6.2. Historical Market Size Value (US$ Billion) Analysis By Therapy, 2018 to 2022
6.3. Current and Future Market Size Value (US$ Billion) Analysis and Forecast By Therapy, 2023 to 2033
6.3.1. Splice-switching ASO
6.3.2. Gapmer ASO
6.3.3. Liposome-delivered siRNA
6.3.4. Delivery of SBillion
6.3.5. Gene Augmentation
6.4. Y-o-Y Growth Trend Analysis By Therapy, 2018 to 2022
6.5. Absolute $ Opportunity Analysis By Therapy, 2023 to 2033
7. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Application
7.1. Introduction / Key Findings
7.2. Historical Market Size Value (US$ Billion) Analysis By Application, 2018 to 2022
7.3. Current and Future Market Size Value (US$ Billion) Analysis and Forecast By Application, 2023 to 2033
7.3.1. Hospitals
7.3.2. Academic & Research Institutes
7.4. Y-o-Y Growth Trend Analysis By Application, 2018 to 2022
7.5. Absolute $ Opportunity Analysis By Application, 2023 to 2033
8. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Region
8.1. Introduction
8.2. Historical Market Size Value (US$ Billion) Analysis By Region, 2018 to 2022
8.3. Current Market Size Value (US$ Billion) Analysis and Forecast By Region, 2023 to 2033
8.3.1. North America
8.3.2. Latin America
8.3.3. Europe
8.3.4. Asia Pacific
8.3.5. Middle East & Africa (MEA)
8.4. Market Attractiveness Analysis By Region
9. North America Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
9.1. Historical Market Size Value (US$ Billion) Trend Analysis By Market Taxonomy, 2018 to 2022
9.2. Market Size Value (US$ Billion) Forecast By Market Taxonomy, 2023 to 2033
9.2.1. By Country
9.2.1.1. The US
9.2.1.2. Canada
9.2.2. By Disorder
9.2.3. By Therapy
9.2.4. By Application
9.3. Market Attractiveness Analysis
9.3.1. By Country
9.3.2. By Disorder
9.3.3. By Therapy
9.3.4. By Application
9.4. Key Takeaways
10. Latin America Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
10.1. Historical Market Size Value (US$ Billion) Trend Analysis By Market Taxonomy, 2018 to 2022
10.2. Market Size Value (US$ Billion) Forecast By Market Taxonomy, 2023 to 2033
10.2.1. By Country
10.2.1.1. Brazil
10.2.1.2. Mexico
10.2.1.3. Rest of Latin America
10.2.2. By Disorder
10.2.3. By Therapy
10.2.4. By Application
10.3. Market Attractiveness Analysis
10.3.1. By Country
10.3.2. By Disorder
10.3.3. By Therapy
10.3.4. By Application
10.4. Key Takeaways
11. Europe Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
11.1. Historical Market Size Value (US$ Billion) Trend Analysis By Market Taxonomy, 2018 to 2022
11.2. Market Size Value (US$ Billion) Forecast By Market Taxonomy, 2023 to 2033
11.2.1. By Country
11.2.1.1. Germany
11.2.1.2. The UK
11.2.1.3. France
11.2.1.4. Spain
11.2.1.5. Italy
11.2.1.6. Rest of Europe
11.2.2. By Disorder
11.2.3. By Therapy
11.2.4. By Application
11.3. Market Attractiveness Analysis
11.3.1. By Country
11.3.2. By Disorder
11.3.3. By Therapy
11.3.4. By Application
11.4. Key Takeaways
12. Asia Pacific Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
12.1. Historical Market Size Value (US$ Billion) Trend Analysis By Market Taxonomy, 2018 to 2022
12.2. Market Size Value (US$ Billion) Forecast By Market Taxonomy, 2023 to 2033
12.2.1. By Country
12.2.1.1. China
12.2.1.2. Japan
12.2.1.3. South Korea
12.2.1.4. Singapore
12.2.1.5. Thailand
12.2.1.6. Indonesia
12.2.1.7. Australia
12.2.1.8. New Zealand
12.2.1.9. Rest of Asia Pacific
12.2.2. By Disorder
12.2.3. By Therapy
12.2.4. By Application
12.3. Market Attractiveness Analysis
12.3.1. By Country
12.3.2. By Disorder
12.3.3. By Therapy
12.3.4. By Application
12.4. Key Takeaways
13. MEA Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
13.1. Historical Market Size Value (US$ Billion) Trend Analysis By Market Taxonomy, 2018 to 2022
13.2. Market Size Value (US$ Billion) Forecast By Market Taxonomy, 2023 to 2033
13.2.1. By Country
13.2.1.1. GCC Countries
13.2.1.2. South Africa
13.2.1.3. Israel
13.2.1.4. Rest of MEA
13.2.2. By Disorder
13.2.3. By Therapy
13.2.4. By Application
13.3. Market Attractiveness Analysis
13.3.1. By Country
13.3.2. By Disorder
13.3.3. By Therapy
13.3.4. By Application
13.4. Key Takeaways
14. Key Countries Market Analysis
14.1. The US
14.1.1. Pricing Analysis
14.1.2. Market Share Analysis, 2022
14.1.2.1. By Disorder
14.1.2.2. By Therapy
14.1.2.3. By Application
14.2. Canada
14.2.1. Pricing Analysis
14.2.2. Market Share Analysis, 2022
14.2.2.1. By Disorder
14.2.2.2. By Therapy
14.2.2.3. By Application
14.3. Brazil
14.3.1. Pricing Analysis
14.3.2. Market Share Analysis, 2022
14.3.2.1. By Disorder
14.3.2.2. By Therapy
14.3.2.3. By Application
14.4. Mexico
14.4.1. Pricing Analysis
14.4.2. Market Share Analysis, 2022
14.4.2.1. By Disorder
14.4.2.2. By Therapy
14.4.2.3. By Application
14.5. Germany
14.5.1. Pricing Analysis
14.5.2. Market Share Analysis, 2022
14.5.2.1. By Disorder
14.5.2.2. By Therapy
14.5.2.3. By Application
14.6. The UK
14.6.1. Pricing Analysis
14.6.2. Market Share Analysis, 2022
14.6.2.1. By Disorder
14.6.2.2. By Therapy
14.6.2.3. By Application
14.7. France
14.7.1. Pricing Analysis
14.7.2. Market Share Analysis, 2022
14.7.2.1. By Disorder
14.7.2.2. By Therapy
14.7.2.3. By Application
14.8. Spain
14.8.1. Pricing Analysis
14.8.2. Market Share Analysis, 2022
14.8.2.1. By Disorder
14.8.2.2. By Therapy
14.8.2.3. By Application
14.9. Italy
14.9.1. Pricing Analysis
14.9.2. Market Share Analysis, 2022
14.9.2.1. By Disorder
14.9.2.2. By Therapy
14.9.2.3. By Application
14.10. China
14.10.1. Pricing Analysis
14.10.2. Market Share Analysis, 2022
14.10.2.1. By Disorder
14.10.2.2. By Therapy
14.10.2.3. By Application
14.11. Japan
14.11.1. Pricing Analysis
14.11.2. Market Share Analysis, 2022
14.11.2.1. By Disorder
14.11.2.2. By Therapy
14.11.2.3. By Application
14.12. South Korea
14.12.1. Pricing Analysis
14.12.2. Market Share Analysis, 2022
14.12.2.1. By Disorder
14.12.2.2. By Therapy
14.12.2.3. By Application
14.13. Singapore
14.13.1. Pricing Analysis
14.13.2. Market Share Analysis, 2022
14.13.2.1. By Disorder
14.13.2.2. By Therapy
14.13.2.3. By Application
14.14. Thailand
14.14.1. Pricing Analysis
14.14.2. Market Share Analysis, 2022
14.14.2.1. By Disorder
14.14.2.2. By Therapy
14.14.2.3. By Application
14.15. Indonesia
14.15.1. Pricing Analysis
14.15.2. Market Share Analysis, 2022
14.15.2.1. By Disorder
14.15.2.2. By Therapy
14.15.2.3. By Application
14.16. Australia
14.16.1. Pricing Analysis
14.16.2. Market Share Analysis, 2022
14.16.2.1. By Disorder
14.16.2.2. By Therapy
14.16.2.3. By Application
14.17. New Zealand
14.17.1. Pricing Analysis
14.17.2. Market Share Analysis, 2022
14.17.2.1. By Disorder
14.17.2.2. By Therapy
14.17.2.3. By Application
14.18. GCC Countries
14.18.1. Pricing Analysis
14.18.2. Market Share Analysis, 2022
14.18.2.1. By Disorder
14.18.2.2. By Therapy
14.18.2.3. By Application
14.19. South Africa
14.19.1. Pricing Analysis
14.19.2. Market Share Analysis, 2022
14.19.2.1. By Disorder
14.19.2.2. By Therapy
14.19.2.3. By Application
14.20. Israel
14.20.1. Pricing Analysis
14.20.2. Market Share Analysis, 2022
14.20.2.1. By Disorder
14.20.2.2. By Therapy
14.20.2.3. By Application
15. Market Structure Analysis
15.1. Competition Dashboard
15.2. Competition Benchmarking
15.3. Market Share Analysis of Top Players
15.3.1. By Regional
15.3.2. By Disorder
15.3.3. By Therapy
15.3.4. By Application
16. Competition Analysis
16.1. Competition Deep Dive
16.1.1. Celsion Corporation
16.1.1.1. Overview
16.1.1.2. Product Portfolio
16.1.1.3. Profitability by Market Segments
16.1.1.4. Sales Footprint
16.1.1.5. Strategy Overview
16.1.1.5.1. Marketing Strategy
16.1.2. Wave Life Sciences
16.1.2.1. Overview
16.1.2.2. Product Portfolio
16.1.2.3. Profitability by Market Segments
16.1.2.4. Sales Footprint
16.1.2.5. Strategy Overview
16.1.2.5.1. Marketing Strategy
16.1.3. Imugene
16.1.3.1. Overview
16.1.3.2. Product Portfolio
16.1.3.3. Profitability by Market Segments
16.1.3.4. Sales Footprint
16.1.3.5. Strategy Overview
16.1.3.5.1. Marketing Strategy
16.1.4. Caperna
16.1.4.1. Overview
16.1.4.2. Product Portfolio
16.1.4.3. Profitability by Market Segments
16.1.4.4. Sales Footprint
16.1.4.5. Strategy Overview
16.1.4.5.1. Marketing Strategy
16.1.5. PYC Therapeutics Ltd.
16.1.5.1. Overview
16.1.5.2. Product Portfolio
16.1.5.3. Profitability by Market Segments
16.1.5.4. Sales Footprint
16.1.5.5. Strategy Overview
16.1.5.5.1. Marketing Strategy
16.1.6. Oxford Biomedica
16.1.6.1. Overview
16.1.6.2. Product Portfolio
16.1.6.3. Profitability by Market Segments
16.1.6.4. Sales Footprint
16.1.6.5. Strategy Overview
16.1.6.5.1. Marketing Strategy
16.1.7. Benitec Biopharma Ltd
16.1.7.1. Overview
16.1.7.2. Product Portfolio
16.1.7.3. Profitability by Market Segments
16.1.7.4. Sales Footprint
16.1.7.5. Strategy Overview
16.1.7.5.1. Marketing Strategy
16.1.8. EdiGene, Inc.
16.1.8.1. Overview
16.1.8.2. Product Portfolio
16.1.8.3. Profitability by Market Segments
16.1.8.4. Sales Footprint
16.1.8.5. Strategy Overview
16.1.8.5.1. Marketing Strategy
16.1.9. GenScript
16.1.9.1. Overview
16.1.9.2. Product Portfolio
16.1.9.3. Profitability by Market Segments
16.1.9.4. Sales Footprint
16.1.9.5. Strategy Overview
16.1.9.5.1. Marketing Strategy
16.1.10. Arctoris Limited
16.1.10.1. Overview
16.1.10.2. Product Portfolio
16.1.10.3. Profitability by Market Segments
16.1.10.4. Sales Footprint
16.1.10.5. Strategy Overview
16.1.10.5.1. Marketing Strategy
17. Assumptions & Acronyms Used18. Research Methodology
List of Tables
Table 1: Global Market Value (US$ Billion) Forecast by Region, 2018 to 2033
Table 2: Global Market Value (US$ Billion) Forecast by Disorder, 2018 to 2033
Table 3: Global Market Value (US$ Billion) Forecast by Therapy, 2018 to 2033
Table 4: Global Market Value (US$ Billion) Forecast by Application, 2018 to 2033
Table 5: North America Market Value (US$ Billion) Forecast by Country, 2018 to 2033
Table 6: North America Market Value (US$ Billion) Forecast by Disorder, 2018 to 2033
Table 7: North America Market Value (US$ Billion) Forecast by Therapy, 2018 to 2033
Table 8: North America Market Value (US$ Billion) Forecast by Application, 2018 to 2033
Table 9: Latin America Market Value (US$ Billion) Forecast by Country, 2018 to 2033
Table 10: Latin America Market Value (US$ Billion) Forecast by Disorder, 2018 to 2033
Table 11: Latin America Market Value (US$ Billion) Forecast by Therapy, 2018 to 2033
Table 12: Latin America Market Value (US$ Billion) Forecast by Application, 2018 to 2033
Table 13: Europe Market Value (US$ Billion) Forecast by Country, 2018 to 2033
Table 14: Europe Market Value (US$ Billion) Forecast by Disorder, 2018 to 2033
Table 15: Europe Market Value (US$ Billion) Forecast by Therapy, 2018 to 2033
Table 16: Europe Market Value (US$ Billion) Forecast by Application, 2018 to 2033
Table 17: Asia Pacific Market Value (US$ Billion) Forecast by Country, 2018 to 2033
Table 18: Asia Pacific Market Value (US$ Billion) Forecast by Disorder, 2018 to 2033
Table 19: Asia Pacific Market Value (US$ Billion) Forecast by Therapy, 2018 to 2033
Table 20: Asia Pacific Market Value (US$ Billion) Forecast by Application, 2018 to 2033
Table 21: MEA Market Value (US$ Billion) Forecast by Country, 2018 to 2033
Table 22: MEA Market Value (US$ Billion) Forecast by Disorder, 2018 to 2033
Table 23: MEA Market Value (US$ Billion) Forecast by Therapy, 2018 to 2033
Table 24: MEA Market Value (US$ Billion) Forecast by Application, 2018 to 2033
List of Charts
Figure 1: Global Market Value (US$ Billion) by Disorder, 2023 to 2033
Figure 2: Global Market Value (US$ Billion) by Therapy, 2023 to 2033
Figure 3: Global Market Value (US$ Billion) by Application, 2023 to 2033
Figure 4: Global Market Value (US$ Billion) by Region, 2023 to 2033
Figure 5: Global Market Value (US$ Billion) Analysis by Region, 2018 to 2033
Figure 6: Global Market Value Share (%) and BPS Analysis by Region, 2023 to 2033
Figure 7: Global Market Y-o-Y Growth (%) Projections by Region, 2023 to 2033
Figure 8: Global Market Value (US$ Billion) Analysis by Disorder, 2018 to 2033
Figure 9: Global Market Value Share (%) and BPS Analysis by Disorder, 2023 to 2033
Figure 10: Global Market Y-o-Y Growth (%) Projections by Disorder, 2023 to 2033
Figure 11: Global Market Value (US$ Billion) Analysis by Therapy, 2018 to 2033
Figure 12: Global Market Value Share (%) and BPS Analysis by Therapy, 2023 to 2033
Figure 13: Global Market Y-o-Y Growth (%) Projections by Therapy, 2023 to 2033
Figure 14: Global Market Value (US$ Billion) Analysis by Application, 2018 to 2033
Figure 15: Global Market Value Share (%) and BPS Analysis by Application, 2023 to 2033
Figure 16: Global Market Y-o-Y Growth (%) Projections by Application, 2023 to 2033
Figure 17: Global Market Attractiveness by Disorder, 2023 to 2033
Figure 18: Global Market Attractiveness by Therapy, 2023 to 2033
Figure 19: Global Market Attractiveness by Application, 2023 to 2033
Figure 20: Global Market Attractiveness by Region, 2023 to 2033
Figure 21: North America Market Value (US$ Billion) by Disorder, 2023 to 2033
Figure 22: North America Market Value (US$ Billion) by Therapy, 2023 to 2033
Figure 23: North America Market Value (US$ Billion) by Application, 2023 to 2033
Figure 24: North America Market Value (US$ Billion) by Country, 2023 to 2033
Figure 25: North America Market Value (US$ Billion) Analysis by Country, 2018 to 2033
Figure 26: North America Market Value Share (%) and BPS Analysis by Country, 2023 to 2033
Figure 27: North America Market Y-o-Y Growth (%) Projections by Country, 2023 to 2033
Figure 28: North America Market Value (US$ Billion) Analysis by Disorder, 2018 to 2033
Figure 29: North America Market Value Share (%) and BPS Analysis by Disorder, 2023 to 2033
Figure 30: North America Market Y-o-Y Growth (%) Projections by Disorder, 2023 to 2033
Figure 31: North America Market Value (US$ Billion) Analysis by Therapy, 2018 to 2033
Figure 32: North America Market Value Share (%) and BPS Analysis by Therapy, 2023 to 2033
Figure 33: North America Market Y-o-Y Growth (%) Projections by Therapy, 2023 to 2033
Figure 34: North America Market Value (US$ Billion) Analysis by Application, 2018 to 2033
Figure 35: North America Market Value Share (%) and BPS Analysis by Application, 2023 to 2033
Figure 36: North America Market Y-o-Y Growth (%) Projections by Application, 2023 to 2033
Figure 37: North America Market Attractiveness by Disorder, 2023 to 2033
Figure 38: North America Market Attractiveness by Therapy, 2023 to 2033
Figure 39: North America Market Attractiveness by Application, 2023 to 2033
Figure 40: North America Market Attractiveness by Country, 2023 to 2033
Figure 41: Latin America Market Value (US$ Billion) by Disorder, 2023 to 2033
Figure 42: Latin America Market Value (US$ Billion) by Therapy, 2023 to 2033
Figure 43: Latin America Market Value (US$ Billion) by Application, 2023 to 2033
Figure 44: Latin America Market Value (US$ Billion) by Country, 2023 to 2033
Figure 45: Latin America Market Value (US$ Billion) Analysis by Country, 2018 to 2033
Figure 46: Latin America Market Value Share (%) and BPS Analysis by Country, 2023 to 2033
Figure 47: Latin America Market Y-o-Y Growth (%) Projections by Country, 2023 to 2033
Figure 48: Latin America Market Value (US$ Billion) Analysis by Disorder, 2018 to 2033
Figure 49: Latin America Market Value Share (%) and BPS Analysis by Disorder, 2023 to 2033
Figure 50: Latin America Market Y-o-Y Growth (%) Projections by Disorder, 2023 to 2033
Figure 51: Latin America Market Value (US$ Billion) Analysis by Therapy, 2018 to 2033
Figure 52: Latin America Market Value Share (%) and BPS Analysis by Therapy, 2023 to 2033
Figure 53: Latin America Market Y-o-Y Growth (%) Projections by Therapy, 2023 to 2033
Figure 54: Latin America Market Value (US$ Billion) Analysis by Application, 2018 to 2033
Figure 55: Latin America Market Value Share (%) and BPS Analysis by Application, 2023 to 2033
Figure 56: Latin America Market Y-o-Y Growth (%) Projections by Application, 2023 to 2033
Figure 57: Latin America Market Attractiveness by Disorder, 2023 to 2033
Figure 58: Latin America Market Attractiveness by Therapy, 2023 to 2033
Figure 59: Latin America Market Attractiveness by Application, 2023 to 2033
Figure 60: Latin America Market Attractiveness by Country, 2023 to 2033
Figure 61: Europe Market Value (US$ Billion) by Disorder, 2023 to 2033
Figure 62: Europe Market Value (US$ Billion) by Therapy, 2023 to 2033
Figure 63: Europe Market Value (US$ Billion) by Application, 2023 to 2033
Figure 64: Europe Market Value (US$ Billion) by Country, 2023 to 2033
Figure 65: Europe Market Value (US$ Billion) Analysis by Country, 2018 to 2033
Figure 66: Europe Market Value Share (%) and BPS Analysis by Country, 2023 to 2033
Figure 67: Europe Market Y-o-Y Growth (%) Projections by Country, 2023 to 2033
Figure 68: Europe Market Value (US$ Billion) Analysis by Disorder, 2018 to 2033
Figure 69: Europe Market Value Share (%) and BPS Analysis by Disorder, 2023 to 2033
Figure 70: Europe Market Y-o-Y Growth (%) Projections by Disorder, 2023 to 2033
Figure 71: Europe Market Value (US$ Billion) Analysis by Therapy, 2018 to 2033
Figure 72: Europe Market Value Share (%) and BPS Analysis by Therapy, 2023 to 2033
Figure 73: Europe Market Y-o-Y Growth (%) Projections by Therapy, 2023 to 2033
Figure 74: Europe Market Value (US$ Billion) Analysis by Application, 2018 to 2033
Figure 75: Europe Market Value Share (%) and BPS Analysis by Application, 2023 to 2033
Figure 76: Europe Market Y-o-Y Growth (%) Projections by Application, 2023 to 2033
Figure 77: Europe Market Attractiveness by Disorder, 2023 to 2033
Figure 78: Europe Market Attractiveness by Therapy, 2023 to 2033
Figure 79: Europe Market Attractiveness by Application, 2023 to 2033
Figure 80: Europe Market Attractiveness by Country, 2023 to 2033
Figure 81: Asia Pacific Market Value (US$ Billion) by Disorder, 2023 to 2033
Figure 82: Asia Pacific Market Value (US$ Billion) by Therapy, 2023 to 2033
Figure 83: Asia Pacific Market Value (US$ Billion) by Application, 2023 to 2033
Figure 84: Asia Pacific Market Value (US$ Billion) by Country, 2023 to 2033
Figure 85: Asia Pacific Market Value (US$ Billion) Analysis by Country, 2018 to 2033
Figure 86: Asia Pacific Market Value Share (%) and BPS Analysis by Country, 2023 to 2033
Figure 87: Asia Pacific Market Y-o-Y Growth (%) Projections by Country, 2023 to 2033
Figure 88: Asia Pacific Market Value (US$ Billion) Analysis by Disorder, 2018 to 2033
Figure 89: Asia Pacific Market Value Share (%) and BPS Analysis by Disorder, 2023 to 2033
Figure 90: Asia Pacific Market Y-o-Y Growth (%) Projections by Disorder, 2023 to 2033
Figure 91: Asia Pacific Market Value (US$ Billion) Analysis by Therapy, 2018 to 2033
Figure 92: Asia Pacific Market Value Share (%) and BPS Analysis by Therapy, 2023 to 2033
Figure 93: Asia Pacific Market Y-o-Y Growth (%) Projections by Therapy, 2023 to 2033
Figure 94: Asia Pacific Market Value (US$ Billion) Analysis by Application, 2018 to 2033
Figure 95: Asia Pacific Market Value Share (%) and BPS Analysis by Application, 2023 to 2033
Figure 96: Asia Pacific Market Y-o-Y Growth (%) Projections by Application, 2023 to 2033
Figure 97: Asia Pacific Market Attractiveness by Disorder, 2023 to 2033
Figure 98: Asia Pacific Market Attractiveness by Therapy, 2023 to 2033
Figure 99: Asia Pacific Market Attractiveness by Application, 2023 to 2033
Figure 100: Asia Pacific Market Attractiveness by Country, 2023 to 2033
Figure 101: MEA Market Value (US$ Billion) by Disorder, 2023 to 2033
Figure 102: MEA Market Value (US$ Billion) by Therapy, 2023 to 2033
Figure 103: MEA Market Value (US$ Billion) by Application, 2023 to 2033
Figure 104: MEA Market Value (US$ Billion) by Country, 2023 to 2033
Figure 105: MEA Market Value (US$ Billion) Analysis by Country, 2018 to 2033
Figure 106: MEA Market Value Share (%) and BPS Analysis by Country, 2023 to 2033
Figure 107: MEA Market Y-o-Y Growth (%) Projections by Country, 2023 to 2033
Figure 108: MEA Market Value (US$ Billion) Analysis by Disorder, 2018 to 2033
Figure 109: MEA Market Value Share (%) and BPS Analysis by Disorder, 2023 to 2033
Figure 110: MEA Market Y-o-Y Growth (%) Projections by Disorder, 2023 to 2033
Figure 111: MEA Market Value (US$ Billion) Analysis by Therapy, 2018 to 2033
Figure 112: MEA Market Value Share (%) and BPS Analysis by Therapy, 2023 to 2033
Figure 113: MEA Market Y-o-Y Growth (%) Projections by Therapy, 2023 to 2033
Figure 114: MEA Market Value (US$ Billion) Analysis by Application, 2018 to 2033
Figure 115: MEA Market Value Share (%) and BPS Analysis by Application, 2023 to 2033
Figure 116: MEA Market Y-o-Y Growth (%) Projections by Application, 2023 to 2033
Figure 117: MEA Market Attractiveness by Disorder, 2023 to 2033
Figure 118: MEA Market Attractiveness by Therapy, 2023 to 2033
Figure 119: MEA Market Attractiveness by Application, 2023 to 2033
Figure 120: MEA Market Attractiveness by Country, 2023 to 2033
