Newly-released In Situ Hybridization industry analysis report by Future Market Insights reveals that global sales of In Situ Hybridization in 2021 were held at USD 1.3 billion. With a 10.6% CAGR, the market is projected to reach a valuation of USD 3.9 billion by 2032.
Fluorescent In Situ Hybridization (FISH) is expected to be the highest revenue-generating technology, accounting for an absolute dollar opportunity of nearly USD 2.5 billion from 2022 to 2032.
| Attribute | Details |
|---|---|
| Global In Situ Hybridization Market (2022) | USD 1.4 billion |
| Global In Situ Hybridization Market (2032) | USD 3.9 billion |
| Global In Situ Hybridization Market CAGR (2022 to 2032) | 10.6% |
| The USA In Situ Hybridization Market CAGR (2022 to 2032) | 10.8% |
| Key Companies Profiled | Merck KGaA; Thermo Fisher Scientific; Agilent Technologies; PerkinElmer; Leica Biosystems Nussloch GmbH; BIO VIEW; NeoGenomics Laboratories, Inc.; Bio-Rad Laboratories, Inc.; Oxford Gene Technology; Advanced Cell Diagnostics, Inc. |
As per the In Situ Hybridization industry research by Future Market Insights - a market research and competitive intelligence provider, historically, from 2017 to 2021, the market value of the In Situ Hybridization industry increased at around 9.9% CAGR, wherein, countries such as the USA, the Kingdom, China, South Korea, and Japan held a significant share in the global market. The market is projected to grow at a CAGR of 10.6% over the coming 10 years.
Some of the key factors driving the market include the rising prevalence of specific disorders, increased investments in in-vitro diagnostics, and technological advances in In Situ Hybridization (ISH).
Various research institutions and organizations have spent the last few years conducting extensive R&D in order to develop a technology that can evaluate the molecular profiles of single cells. For example, BIO-PROTOCOL created the Proximity Ligation in the In Situ Hybridization process. The method is expected to be high-performing, low-cost, quick multiplex, and simple to apply.
In situ hybridization technology has become more economical, making it more accessible to developing countries, which are more susceptible to infections and diseases. Regulatory organizations have implemented a variety of regulations and measures to raise public awareness. In August 2021, for example, the Federal Capital Public Health Agency in Nigeria cooperated with WHO to raise infectious illness awareness.
The utilization of ISH products has grown in recent years, resulting in an increase in the number of specialist contract research organizations. Reveal Biosciences, for example, uses in situ hybridization and other methodologies to deliver tissue research and innovative tissue technology services with strict legal capacity and high samples throughout.
For the past several years, cancer cases have been on the rise all around the world. Over the last few decades, extensive investigations on human diseases have identified recurrent genetic aberrations as potential driving factors for a range of malignancies.
Cytogenetic tests, such as ISH, aid in the combination of IHC and DNA FISH in situ, allowing researchers to create, discover and execute next-generation diagnostic approaches. Direct imaging of gene expression in situ at the RNA level gives a new perspective on the interaction between cancer cells and the tumor microenvironment as cancer progresses.
Furthermore, according to a study conducted by McMaster University in Canada, the number of people living with hemophilia has tripled to 1,125,000, up from 400,000 previously. Canada, France, Italy, Australia, the United Kingdom, and New Zealand are the countries most affected. The market is anticipated to benefit from this growth.
North America is expected to be the most lucrative region in the In Situ Hybridization Market throughout the analysis period. The market in the region is expected to be propelled by significant expenditure in healthcare Research and Development (R&D). The market in North America is projected to cross a valuation of USD 1.5 billion by 2032.
The USA dominated the In Situ Hybridization market in 2021, accounting for 44.9% of the total revenue. The existence of a large number of market players, as well as encouraging research programs by the regional government, can be credited for the regional market growth.
Other variables contributing to the country's dominance throughout the projection period include high healthcare spending and strict FDA and Health Canada rules. The USA In Situ Hybridization market has the most patents, whereas the Asia Pacific market has a greater marginal rise than the rest of the world. The presence of Health Canada-funded research initiatives and institutes is estimated to spur the market by a little margin.
The In Situ Hybridization market in the United Kingdom was valued at USD 72.5 million in 2021. The market in the country is expected to reach nearly USD 217.6 million by 2032. From 2022 to 2032, the market is likely to witness an absolute dollar opportunity of USD 147.1 million, growing at a CAGR of 11.9%
The In Situ Hybridization market in Japan is projected to reach a valuation of USD 183.8 million by 2032, growing at a CAGR of 10.1% from 2022 to 2032. The market is likely to garner an absolute dollar opportunity of USD 114.3 million from 2022 to 2032.
The market in South Korea is expected to reach a USD 75.1 million market value by 2032, growing at a CAGR of 8.5% from 2022 to 2032. During this period, the market is likely to gross an absolute dollar growth of USD 42.3 million.
The Fluorescent In Situ Hybridization (FISH) segment held the largest share of In Situ Hybridization market in 2021, accounting for around 54% of total revenue. This is due to the vast range of uses, including the diagnosis of congenital illnesses such as Edward's Syndrome and Down's Syndrome. The increased use of FISH technology as a result of the rising prevalence and treatment of such diseases is likely to accelerate In Situ Hybridization market growth.
The FISH market's growth is being fueled by low-cost technical advancements. For example, in May 2021, a group of researchers published a report claiming that using chromogen-based RNA in situ hybridization to identify druggable cytokines in atopic dermatitis and psoriasis is an efficient way. Technological progress broadens the scope of In Situ Hybridization and propels segment expansion.
The DNA probe segment held the largest share of in situ hybridization market in 2021, accounting for over 50% of total revenue. However, due to the development of novel nucleic acid-based diagnostic assays and instruments for studying DNA and RNA molecules, the demand for RNA probes grew at a faster rate in the anticipated timeframe.
By hybridization, an RNA probe can indicate the presence of similar nucleic acid sequences. The use of RNA as a hybridization technique is growing due to various advantages, including the fact that the probes are generated in vitro and may be used in practically all applications instead of DNA probes.
Revenue through application dominated the in situ hybridization market in 2021, accounting for over 35% of the total revenue. The expansion is expected to be fueled by an increase in the number of cancer cases. According to the American Cancer Society, about 1.9 million additional cancer cases are projected in the United States in 2021. With the surge in cancer cases, in situ hybridization methods for speedy and accurate diagnosis are in high demand.
Cancer is caused by a variety of reasons, including an aging population, poor health, and the environment. Various organizations are conducting cancer research and are encouraging advancements in cancer therapy. For example, the American Institute for Cancer Research funded around USD 110 million in cancer research grants from 2020 to 2021.
During the pinnacle of the epidemic, there was a significant drop in cancer and precancer diagnoses, owing to a decline in the number of screening tests done. In recent months, these characteristics may have hampered the utility of In Situ Hybridization as a molecular tool for cancer diagnosis. However, in the forthcoming years, the considerable development of FISH probes to visualize SARS-CoV-2 RNA in infected cells can have a favorable impact on the sector.
COVID-19 was also a motivating force behind the FISH market's expansion. The University of Oxford and the University of Warwick partnered in June 2021 to develop an in situ hybridization approach for detecting the COVID-19 virus in twenty minutes. This method has previously been used to detect diseases such as the Epstein-Barr virus and HIV inside cells. The In Situ Hybridization market growth is likely to accelerate in the near future because of these changes.
Some of the key players such as Merck KGaA, Thermo Fisher Scientific, Agilent Technologies, PerkinElmer, and Leica Biosystems Nussloch GmbH.
Some of the recent developments of key In Situ Hybridization providers are as follows:
Similarly, recent developments related to companies offering In Situ Hybridization have been tracked by the team at Future Market Insights, which are available in the full report.
Table 1: Global Market Value (US$ million), By Technology, 2017 to 2021
Table 2: Global Market Value (US$ million), By Technology, 2022 to 2032
Table 3: Global Market Value (US$ million), By Probe Type, 2017 to 2021
Table 4: Global Market Value (US$ million), By Probe Type, 2022 to 2032
Table 5: Global Market Value (US$ million), By Product Type, 2017 to 2021
Table 6: Global Market Value (US$ million), By Product Type, 2022 to 2032
Table 7: Global Market Value (US$ million), By Application, 2017 to 2021
Table 8: Global Market Value (US$ million), By Application, 2022 to 2032
Table 9: Global Market, By Region, 2017 to 2021
Table 10: Global Market, By Region, 2022 to 2032
Table 11: North America Market Value (US$ million),By Technology, 2017 to 2021
Table 12: North America Market Value (US$ million),By Technology, 2022 to 2032
Table 13: North America Market Value (US$ million), By Probe Type, 2017 to 2021
Table 14: North America Market Value (US$ million), By Probe Type, 2022 to 2032
Table 15: North America Market Value (US$ million), By Product Type, 2017 to 2021
Table 16: North America Market Value (US$ million), By Product Type, 2022 to 2032
Table 17: North America Market Value (US$ million), By Application, 2017 to 2021
Table 18: North America Market Value (US$ million), By Application, 2022 to 2032
Table 19: North America Market, By Country, 2017 to 2021
Table 20: North America Market, By Country, 2022 to 2032
Table 21: Latin America Market Value (US$ million), By Technology, 2017 to 2021
Table 22: Latin America Market Value (US$ million), By Technology, 2022 to 2032
Table 23: Latin America Market Value (US$ million), By Probe Type, 2017 to 2021
Table 24: Latin America Market Value (US$ million), By Probe Type, 2022 to 2032
Table 25: Latin America Market Value (US$ million), By Product Type, 2017 to 2021
Table 26: Latin America Market Value (US$ million), By Product Type, 2022 to 2032
Table 27: Latin America Market Value (US$ million), By Application, 2017 to 2021
Table 28: Latin America Market Value (US$ million), By Application, 2022 to 2032
Table 29: Latin America Market, By Country, 2017 to 2021
Table 30: Latin America Market, By Country, 2022 to 2032
Table 31: Europe Market Value (US$ million), By Technology, 2017 to 2021
Table 32: Europe Market Value (US$ million), By Technology, 2022 to 2032
Table 33: Europe Market Value (US$ million), By Probe Type, 2017 to 2021
Table 34: Europe Market Value (US$ million), By Probe Type, 2022 to 2032
Table 35: Europe Market Value (US$ million), By Product Type, 2017 to 2021
Table 36: Europe Market Value (US$ million), By Product Type, 2022 to 2032
Table 37: Europe Market Value (US$ million), By Application, 2017 to 2021
Table 38: Europe Market Value (US$ million), By Application, 2022 to 2032
Table 39: Europe Market, By Country, 2017 to 2021
Table 40: Europe Market, By Country, 2022 to 2032
Table 41: Asia Pacific Market Value (US$ million), By Technology, 2017 to 2021
Table 42: Asia Pacific Market Value (US$ million), By Technology, 2022 to 2032
Table 43: Asia Pacific Market Value (US$ million), By Probe Type, 2017 to 2021
Table 44: Asia Pacific Market Value (US$ million), By Probe Type, 2022 to 2032
Table 45: Asia Pacific Market Value (US$ million), By Product Type, 2017 to 2021
Table 46: Asia Pacific Market Value (US$ million), By Product Type, 2022 to 2032
Table 47: Asia Pacific Market Value (US$ million), By Application, 2017 to 2021
Table 48: Asia Pacific Market Value (US$ million), By Application, 2022 to 2032
Table 49: Asia Pacific Market, By Country, 2017 to 2021
Table 50: Asia Pacific Market, By Country, 2022 to 2032
Table 51: MEA Market Value (US$ million), By Technology, 2017 to 2021
Table 52: MEA Market Value (US$ million), By Technology, 2022 to 2032
Table 53: MEA Market Value (US$ million), By Probe Type, 2017 to 2021
Table 54: MEA Market Value (US$ million), By Probe Type, 2022 to 2032
Table 55: MEA Market Value (US$ million), By Product Type, 2017 to 2021
Table 56: MEA Market Value (US$ million), By Product Type, 2022 to 2032
Table 57: MEA Market Value (US$ million), By Application, 2017 to 2021
Table 58: MEA Market Value (US$ million), By Application, 2022 to 2032
Table 59: MEA Market, By Country, 2017 to 2021
Table 60: MEA Market, By Country, 2022 to 2032
Figure 1: Global Market Value (US$ million) and Year-on-Year Growth, 2017 to 2032
Figure 2: Global Market Absolute $ Historical Gain (2017 to 2021) and Opportunity (2022 to 2032), US$ million
Figure 3: Global Market Share, By Technology, 2022 to 2032
Figure 4: Global Market Y-o-Y Growth Projections, By Technology - 2022 to 2032
Figure 5: Global Market Attractiveness Index, By Technology - 2022 to 2032
Figure 6: Global Market Share, By Probe Type, 2022 to 2032
Figure 7: Global Market Y-o-Y Growth Projections, By Probe Type - 2022 to 2032
Figure 8: Global Market Attractiveness Index, By Probe Type - 2022 to 2032
Figure 9: Global Market Share, By Technology, 2022 to 2032
Figure 10: Global Market Y-o-Y Growth Projections, By Application - 2022 to 2032
Figure 11: Global Market Attractiveness Index, By Application - 2022 to 2032
Figure 12: Global Market Share, By Product Type, 2022 to 2032
Figure 13: Global Market Y-o-Y Growth Projections, By Product Type - 2022 to 2032
Figure 14: Global Market Attractiveness Index, By Product Type - 2022 to 2032
Figure 15: Global Market Share, By Region, 2022 to 2032
Figure 16: Global Market Y-o-Y Growth Projections, By Region - 2022 to 2032
Figure 17: Global Market Attractiveness Index, By Region - 2022 to 2032
Figure 18: North America Market Value (US$ million) and Year-on-Year Growth, 2017-2032
Figure 19: North America Market Absolute $ Opportunity Historical (2017 to 2021) and Forecast Period (2022 to 2032), US$ million
Figure 20: North America Market Share, By Technology, 2022 to 2032
Figure 21: North America Market Y-o-Y Growth Projections, By Technology - 2022 to 2032
Figure 22: North America Market Attractiveness Index, By Technology - 2022 to 2032
Figure 23: North America Market Share, By Probe Type, 2022 to 2032
Figure 24: North America Market Y-o-Y Growth Projections, By Probe Type - 2022 to 2032
Figure 25: North America Market Attractiveness Index, By Probe Type - 2022 to 2032
Figure 26: North America Market Share, By Technology, 2022 to 2032
Figure 27: North America Market Y-o-Y Growth Projections, By Application - 2022 to 2032
Figure 28: North America Market Attractiveness Index, By Application - 2022 to 2032
Figure 29: North America Market Share, By Product Type, 2022 to 2032
Figure 30: North America Market Y-o-Y Growth Projections, By Product Type - 2022 to 2032
Figure 31: North America Market Attractiveness Index, By Product Type - 2022 to 2032
Figure 32: North America Market Share, By Country, 2022 to 2032
Figure 33: North America Market Y-o-Y Growth Projections, By Country - 2022 to 2032
Figure 34: North America Market Attractiveness Index, By Country - 2022 to 2032
Figure 35: Latin America Market Value (US$ million) and Year-on-Year Growth, 2017-2032
Figure 36: Latin America Market Absolute $ Opportunity Historical (2017 to 2021) and Forecast Period (2022 to 2032), US$ million
Figure 37: Latin America Market Share, By Technology, 2022 to 2032
Figure 38: Latin America Market Y-o-Y Growth Projections, By Technology - 2022 to 2032
Figure 39: Latin America Market Attractiveness Index, By Technology - 2022 to 2032
Figure 40: Latin America Market Share, By Probe Type, 2022 to 2032
Figure 41: Latin America Market Y-o-Y Growth Projections, By Probe Type - 2022 to 2032
Figure 42: Latin America Market Attractiveness Index, By Probe Type - 2022 to 2032
Figure 43: Latin America Market Share, By Technology, 2022 to 2032
Figure 44: Latin America Market Y-o-Y Growth Projections, By Application - 2022 to 2032
Figure 45: Latin America Market Attractiveness Index, By Application - 2022 to 2032
Figure 46: Latin America Market Share, By Product Type, 2022 to 2032
Figure 47: Latin America Market Y-o-Y Growth Projections, By Product Type - 2022 to 2032
Figure 48: Latin America Market Attractiveness Index, By Product Type - 2022 to 2032
Figure 49: Latin America Market Share, By Country, 2022 to 2032
Figure 50: Latin America Market Y-o-Y Growth Projections, By Country - 2022 to 2032
Figure 51: Latin America Market Attractiveness Index, By Country - 2022 to 2032
Figure 52: Europe Market Value (US$ million) and Year-on-Year Growth, 2017-2032
Figure 53: Europe Market Absolute $ Opportunity Historical (2017 to 2021) and Forecast Period (2022 to 2032), US$ million
Figure 54: Europe Market Share, By Technology, 2022 to 2032
Figure 55: Europe Market Y-o-Y Growth Projections, By Technology - 2022 to 2032
Figure 56: Europe Market Attractiveness Index, By Technology - 2022 to 2032
Figure 57: Europe Market Share, By Probe Type, 2022 to 2032
Figure 58: Europe Market Y-o-Y Growth Projections, By Probe Type - 2022 to 2032
Figure 59: Europe Market Attractiveness Index, By Probe Type - 2022 to 2032
Figure 60: Europe Market Share, By Technology, 2022 to 2032
Figure 61: Europe Market Y-o-Y Growth Projections, By Application - 2022 to 2032
Figure 62: Europe Market Attractiveness Index, By Application - 2022 to 2032
Figure 63: Europe Market Share, By Product Type, 2022 to 2032
Figure 64: Europe Market Y-o-Y Growth Projections, By Product Type - 2022 to 2032
Figure 65: Europe Market Attractiveness Index, By Product Type - 2022 to 2032
Figure 66: Europe Market Share, By Country, 2022 to 2032
Figure 67: Europe Market Y-o-Y Growth Projections, By Country - 2022 to 2032
Figure 68: Europe Market Attractiveness Index, By Country - 2022 to 2032
Figure 69: MEA Market Value (US$ million) and Year-on-Year Growth, 2017-2032
Figure 70: MEA Market Absolute $ Opportunity Historical (2017 to 2021) and Forecast Period (2022 to 2032), US$ million
Figure 71: MEA Market Share, By Technology, 2022 to 2032
Figure 72: MEA Market Y-o-Y Growth Projections, By Technology - 2022 to 2032
Figure 73: MEA Market Attractiveness Index, By Technology - 2022 to 2032
Figure 74: MEA Market Share, By Probe Type, 2022 to 2032
Figure 75: MEA Market Y-o-Y Growth Projections, By Probe Type - 2022 to 2032
Figure 76: MEA Market Attractiveness Index, By Probe Type - 2022 to 2032
Figure 77: MEA Market Share, By Technology, 2022 to 2032
Figure 78: MEA Market Y-o-Y Growth Projections, By Application - 2022 to 2032
Figure 79: MEA Market Attractiveness Index, By Application - 2022 to 2032
Figure 80: MEA Market Share, By Product Type, 2022 to 2032
Figure 81: MEA Market Y-o-Y Growth Projections, By Product Type - 2022 to 2032
Figure 82: MEA Market Attractiveness Index, By Product Type - 2022 to 2032
Figure 83: MEA Market Share, By Country, 2022 to 2032
Figure 84: MEA Market Y-o-Y Growth Projections, By Country - 2022 to 2032
Figure 85: MEA Market Attractiveness Index, By Country - 2022 to 2032
Figure 86: Asia Pacific Market Value (US$ million) and Year-on-Year Growth, 2017-2032
Figure 87: Asia Pacific Market Absolute $ Opportunity Historical (2017 to 2021) and Forecast Period (2022 to 2032), US$ million
Figure 88: Asia Pacific Market Share, By Technology, 2022 to 2032
Figure 89: Asia Pacific Market Y-o-Y Growth Projections, By Technology - 2022 to 2032
Figure 90: Asia Pacific Market Attractiveness Index, By Technology - 2022 to 2032
Figure 91: Asia Pacific Market Share, By Probe Type, 2022 to 2032
Figure 92: Asia Pacific Market Y-o-Y Growth Projections, By Probe Type - 2022 to 2032
Figure 93: Asia Pacific Market Attractiveness Index, By Probe Type - 2022 to 2032
Figure 94: Asia Pacific Market Share, By Technology, 2022 to 2032
Figure 95: Asia Pacific Market Y-o-Y Growth Projections, By Application - 2022 to 2032
Figure 96: Asia Pacific Market Attractiveness Index, By Application - 2022 to 2032
Figure 97: Asia Pacific Market Share, By Product Type, 2022 to 2032
Figure 98: Asia Pacific Market Y-o-Y Growth Projections, By Product Type - 2022 to 2032
Figure 99: Asia Pacific Market Attractiveness Index, By Product Type - 2022 to 2032
Figure 100: Asia Pacific Market Share, By Country, 2022 to 2032
Figure 101: Asia Pacific Market Y-o-Y Growth Projections, By Country - 2022 to 2032
Figure 102: Asia Pacific Market Attractiveness Index, By Country - 2022 to 2032
The global In Situ Hybridization market is worth more than USD 1.4 billion at present.
The value of In Situ Hybridization is projected to increase at a CAGR of around 10.6% from 2022 to 2032.
The value of In Situ Hybridization increased at a CAGR of around 9.9% from 2017 to 2021.
Top five players of In Situ Hybridization market include Merck KGaA, Thermo Fisher Scientific, Agilent Technologies, PerkinElmer, and Leica Biosystems Nussloch GmbH
The top 5 countries driving demand for In Situ Hybridization are the USA, the United Kingdom., China, Japan, South Korea
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