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Liquid Chromatography Systems Market

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Liquid Chromatography Systems Market Outlook

The current valuation of the liquid chromatography systems market in 2022 is US$ 4.44 billion and it is projected to grow at a CAGR of 5.9% within the period between 2022-2032 to reach a market size of US$ 7.03 billion .

Liquid Chromatography Market Valuation (2022)

$4.44 Bn

Liquid Chromatography Market Valuation (2032)

$7.03 Bn



Chromatography methods are used to organic and inorganic compounds such as separate proteins, nucleic acids, or small molecules in complex mixtures and others. Liquid chromatography (LC) separates molecules in a liquid mobile phase by means of a solid stationary phase. It is basically a technique which separates a sample into its individual parts.

This separation takes place based on the interactions of the sample with the mobile and stationary phases. Liquid chromatography procedure can be directed in various combination of possible mobile phases and stationary phases. The combinations are categorized with more than one name and the names focus on many different aspects of liquid chromatography methods.

Liquid chromatography generally uses small particles packed and operating at comparatively high pressure, and is denoted as high performance liquid chromatography (HPLC). Modern Liquid Chromatography-Mass Spectrometry (LC-MS) methods use HPLC instrumentation, basically for sample introduction. Liquid chromatography can be used for analytical or preparative applications.

Irrespective of the interactions that are being brought, liquid column chromatography is taken up in six steps: Column equilibration, Sample loading, Washing, Elution, Final column washing and Column regeneration.

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Important factors driving the growth of the liquid chromatography market are

  • Rampant and sustained technological developments, bolstering the effectiveness of liquid chromatography systems, have had a positive impact on the market.
  • Liquid chromatography was one of the few markets to be positively impacted by the pandemic. During the pandemic, high-performance, liquid chromatography techniques became a reliable component for developing life-saving vaccines and other disease-detecting systems.
  • Rising government funding towards medical, pharmaceutical development, and research has led to the expansion of the liquid chromatography market.
  • Diverse and critical applications across a versatile range of industries including pharma, food quality testing, and environmental quality assessment.
  • The technique’s and important applications in drug testing to determine the accurate date of expiration.
  • Increasing adoption of liquid chromatography-based systems and instruments in research laboratories.

Overview of the Liquid Chromatography Systems Market

The liquid chromatography systems market can be briefly classified, based on the product, into Instruments, Accessories, and Software. Large-scale applications of high-performance liquid chromatography across laboratories have made the instruments segment of the market the most profitable one, with a revenue share of over 40%. This is due to rampant innovation in the technology, which has produced highly accurate HPLC-based detectors for labs.

A few recent innovations in the instruments segment are Shimadzu Corporation’s I-Series LC-2050/LC-2060 integrated HPLC system and Activated Research Company’s Solvere carbon selective detector. The likes of Agilent Technologies are driving growth in the accessories segment through launches like the new AdvanceBio SEC PEEK-lined stainless-steel column.

In the software segment, Shimadzu Corporation recently launched the LabSolutions MD software. This is further boosted by an improvement in column chemistry and filtration techniques used for the accessories. Corporations such as Axcend are developing portable systems based on HPLC with wide-ranging utility across different industries.

In the pharma industry, there is a rise in the usage of chiral compounds, which demands greater innovations in the existing liquid chromatography systems. Since a majority of new pharmaceutical developments indicate the presence of chiral compounds, this could prove detrimental to the growth of the liquid chromatography systems market.

The different technologies used in liquid chromatography systems are High-Performance Liquid Chromatography (HPLC), Ultra High-Pressure Liquid Chromatography (UHPLC), and Low-Pressure Liquid Chromatography (LPLC). Amongst these, HPLC is the most widely employed technique.

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Liquid Chromatography Systems: Region-Wise Outlook

North America is at the helm of the race, accounting for more than 30% of the global market valuation. Technological and scientific advancement, coupled with high investment in research and development activities, has led to a boom in the liquid chromatography systems market in the North American region. Several giants in the market are based out of this region, including Thermo Fisher Scientific and Agilent Technologies. The growing geriatric population and those in need of medical care in the Asia Pacific region have led to the market’s growth in the region. This growth is further enhanced by the production of biosimilars in countries like India and China.

Liquid Chromatography Systems Market: Drivers and Restraints

Liquid chromatography is a less expensive procedure than HPLC and Gas Chromatography. This could be considered as a most significant driving factor responsible for the growth of liquid chromatography systems market. Moreover some instruments for liquid chromatography are readily available in laboratories which is further providing boost to the growth of growing liquid chromatography systems market.

However, limited sensitive and specific of detectors in applications involving complex samples could be the major restraints for liquid chromatography systems market.

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Liquid Chromatography Systems Market: Overview

In partition chromatography method, the stationary phase and the mobile phase both are liquid. The stationary phase liquid would be an incompatible liquid with the mobile phase. Liquid-solid chromatography is related to partition chromatography.

The only difference is that the stationary phase has been substituted with a bonded rigid silica or silica based component. Ion-exchange chromatography technique is used to separate and determine ions on columns that have a low ion exchange capacity.

Size exclusion chromatography separates molecules by their size. Further technological advancements have improved the convenience and ease of use of liquid chromatography devices.

Liquid Chromatography Systems Market: Region-wise Outlook

The global liquid chromatography systems marketis classified into seven regions namely, North America, Latin America, Western Europe, Eastern Europe, Asia-Pacific excluding Japan (APEJ), Japan, Middle East and Africa (MEA).

North America is expected to dominate the liquid chromatography systems market in terms of both revenue and demand generation owing to greater awareness on technological advancement followed by Western Europe. However, markets in Latin America and Asia-Pacific could prove lucrative in terms of market opportunities considering factors like organized healthcare structure in terms of disease diagnosis, increasing initiatives for food safety and food detection and increasing healthcare spending.

Liquid Chromatography Systems Market: Key Players

Some of the major companies operating in manufacturing of liquid chromatography systems include Thermo Fisher Scientific Inc., Agilent Technologies, PerkinElmer, Inc., Shimadzu Corporation, Waters Corporation, Phenomenex, Inc. among others.

The report covers exhaustive analysis on

  • Market Segments
  • Market Dynamics
  • Market Size
  • Supply & Demand
  • Current Trends/Issues/Challenges
  • Competition & Companies involved
  • Technology
  • Value Chain

Regional analysis includes

  • North America (U.S., Canada)
  • Latin America (Mexico, Brazil)
  • Western Europe (Germany, Italy, U.K, Spain, France, Nordic countries, BENELUX)
  • Eastern Europe (Russia, Poland, Rest Of Eastern Europe)
  • Asia Pacific Excluding Japan (China, India, ASEAN, Australia & New Zealand)
  • Japan
  • Middle East and Africa (GCC, S. Africa, N. Africa, Rest Of MEA)

The report is a compilation of first-hand information, qualitative and quantitative assessment by industry analysts, inputs from industry experts and industry participants across the value chain. The report provides in-depth analysis of parent market trends, macro-economic indicators and governing factors along with market attractiveness as per segments. The report also maps the qualitative impact of various market factors on market segments and geographies.

Liquid Chromatography Systems Market: Segmentation

Liquid chromatography systems market is segmented based on product type, applications, end user and geography.

Based on product type, liquid chromatography systems market is segmented as follows:

  • Normal-phase liquid chromatography (NPLC)
  • Reversed-phase liquid chromatography
  • (RPLC)
  • Ion Exchange Chromatography (IELC)
  • Size exclusion liquid chromatography (SELC)

Based on applications, liquid chromatography systems market is segmented as follows:

  • BiomedicalAnalysis
  • Food Product Analysis
  • Oils and fats Analysis
  • Others

Based on end user, liquid chromatography systems market is segmented as follows:

  • Research laboratories
  • Clinical Research Laboratories
  • Food Safety Laboratories
  • Diagnostic centers
  • Educational Institutes
  • Contract Research Organizations

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Portable Chromatography Systems Market

Published : July 2022

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